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New Approaches to Functional Process Discovery in HPV 16-Associated Cervical Cancer Cells by Gene Ontology

Kim YW, Suh MJ, Bae JS, Bae SM, Yoon JH, Hur SY, Kim JH, Ro DY, Lee JM, Namkoong S, Kim CK, Ahn WS

  • KMID: 1972898
  • Cancer Res Treat.
  • 2003 Aug;35(4):304-313.
No abstract available.
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An Ontology-Based GIS for Genomic Data Management of Rumen Microbes

Jelokhani-Niaraki S, Tahmoorespur M, Minuchehr , Nassiri MR

During recent years, there has been exponential growth in biological information. With the emergence of large datasets in biology, life scientists are encountering bottlenecks in handling the biological data. This...
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Estimation of the Genetic Substitution Rate of Hanwoo and Holstein Cattle Using Whole Genome Sequencing Data

Lee YS, Shin D

Despite the importance of mutation rate, some difficulties exist in estimating it. Next-generation sequencing (NGS) data yields large numbers of single-nucleotide polymorphisms, which can make it feasible to estimate substitution...
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GSnet: An Integrated Tool for Gene Set Analysis and Visualization

Choi YJ, Woo HG, Yu U

  • KMID: 2166269
  • Genomics Inform.
  • 2007 Sep;5(3):133-136.
The Gene Set network viewer (GSnet) visualizes the functional enrichment of a given gene set with a protein interaction network and is implemented as a plug-in for the Cytoscape platform....
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FCAnalyzer: A Functional Clustering Analysis Tool for Predicted Transcription Regulatory Elements and Gene Ontology Terms

Kim SB, Ryu GM, Kim YJ, Heo JY, Park C, Oh BS, Kim HL, Kimm KC, Kim KW, Kim YY

  • KMID: 2166249
  • Genomics Inform.
  • 2007 Mar;5(1):10-18.
Numerous studies have reported that genes with similar expression patterns are co-regulated. From gene expression data, we have assumed that genes having similar expression pattern would share similar transcription factor...
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Identification of Gene Expression and Gene Ontology Classification by Differential Display RT-PCR in Human Cervical Squamous Cell Carcinoma

Seo MJ, Bae SM, Park KM, Kim BH, Kim YW, Seo KY, Seo KA, Kim YW, Hur SY, Ro DY, Lee JM, Namkoong S, Kim CK, Ahn WS

  • KMID: 2272306
  • Korean J Obstet Gynecol.
  • 2004 Apr;47(4):684-694.
OBJECTIVE: The molecular pathology of cervical cancer associated with human papillomavirus infection is presently unclear. In an effort to clarify the multiple interactions of a number of genes involved in...
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Improved Algorithms for the Identification of Yeast Proteins and Significant Transcription Factor and Motif Analysis

Lee SW, Hong SE, Lee KY, Choi DI, Chung HY, Hur CG

  • KMID: 2166220
  • Genomics Inform.
  • 2006 Jun;4(2):87-93.
With the rapid development of MS technologiesy, the demands for a more sophisticated MS interpretation algorithm haves grown as well. We have developed a new protein fingerprinting method using a...
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Analysis of Disease Progression-Associated Gene Expression Profile in Fibrillin-1 Mutant Mice: New Insight into Molecular Pathogenesis of Marfan Syndrome

Kim KL, Choi C, Suh W

  • KMID: 2170654
  • Biomol Ther.
  • 2014 Mar;22(2):143-148.
Marfan syndrome (MFS) is a dominantly inherited connective tissue disorder caused by mutations in the gene encoding fibrillin-1 (FBN1) and is characterized by aortic dilatation and dissection, which is the...
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Transcriptome Analysis Identifies an Attenuated Local Immune Response in Invasive Nonfunctioning Pituitary Adenomas

Kim YH, Kim JH

BACKGROUND: Invasive nonfunctioning pituitary adenomas (NFPAs) remain challenging due to their high complication rate and poor prognosis. We aimed to identify the distinctive molecular signatures of invasive NFPAs, compared with...
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Differential Gene Expression in Placenta of Term Pregnant Women with and without Labor using cDNA Microarray

Kim A, Kim OK, Seo MW, Yang DE, Ahn HY, Park IY, Lee GS, Shin JC

  • KMID: 2280612
  • Korean J Perinatol.
  • 2007 Dec;18(4):370-377.
OBJECTIVE:cDNA microarray technology was used to comprehensively analyze the gene expression in the placenta of term women with labor compared to without labor. METHODS:Placental tissue was obtained from patients in spontaneous...
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Differential Gene Expression Common to Acquired and Intrinsic Resistance to BRAF Inhibitor Revealed by RNA-Seq Analysis

Ahn JH, Hwang SH, Cho HS, Lee M

Melanoma cells have been shown to respond to BRAF inhibitors; however, intrinsic and acquired resistance limits their clinical application. In this study, we performed RNA-Seq analysis with BRAF inhibitor-sensitive (A375P)...
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In silico approach to calculate the transcript capacity

Lee YS, Won KH, Oh JD, Shin D

We sought the novel concept, transcript capacity (TC) and analyzed TC. Our approach to estimate TC was through an in silico method. TC refers to the capacity that a transcript...
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Exploring the Key Genes and Pathways of Osteoarthritis in Knee Cartilage in a Rat Model Using Gene Expression Profiling

Ren YM, Zhao X, Yang T, Duan YH, Sun YB, Zhao WJ, Tian MQ

PURPOSE: To compare differentially expressed genes (DEGs) mediating osteoarthritis (OA) in knee cartilage and in normal knee cartilage in a rat model of OA and to identify their impact on...
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Human Embryonic Stem Cell Derived from Early Stage Fertilized Ovum: Non Immunogenic and Universal, Neuronal and Non-neuronal Cell Lines

Shroff G, Srivastav , Shroff R

BACKGROUND: Human embryonic stem cells (hESCs) have the potential to treat various human disorders currently labeled as incurable and/or terminal illness. However, the fear that the patients' immune system would...
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Proteomic Classification and Identification of Proteins Related to Tissue Healing of Platelet-Rich Plasma

Lee HW, Choi KH, Kim JY, Kim KO, Haotian B, Yuxuan L, Noh KC

BACKGROUND: Platelet-rich plasma (PRP) is a plasma component of autologous blood containing a high concentration of platelets. PRP is used to promote healing of damaged tissues. However, there are not...
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Comparison of As2O3 and As4O6 in the Detection of SiHa Cervical Cancer Cell Growth Inhibition Pathway

Kim YW, Bae SM, Lee KH, Lee JM, Namkoong S, Lee IP, Kim CK, Seo JS, Sin JI, Kim YW, Ahn WS

  • KMID: 2166140
  • Cancer Res Treat.
  • 2004 Aug;36(4):255-262.
PURPOSE: An arsenical compound, As2O3, has been reported to be effective for treating acute leukemia and inducing apoptosis in many different tumor cells. In this study, the ability of As4O6...
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Identification of the Genes Involved in the Fruiting Body Production and Cordycepin Formation of Cordyceps militaris Fungus

Zheng ZL, Qiu XH, Han RC

A mutant library of Cordyceps militaris was constructed by improved Agrobacterium tumefaciens-mediated transformation and screened for degradation features. Six mutants with altered characters in in vitro and in vivo fruiting...
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Expression Profiling of the Cellular Processes in Uterine Leiomyomas: Omic Approaches and IGF-2 Association with Leiomyosarcomas

Bae SM, Kim YW, Lee JM, Namkoong S, Kim CK, Ahn WS

  • KMID: 1807304
  • Cancer Res Treat.
  • 2004 Feb;36(1):31-42.
PURPOSE: This study utilized both cDNA microarray and 2D protein gel electrophoresis technology to investigate the multiple interactions of the genes and proteins involved in the pathophysiology of uterine leiomyomas....
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Genome-Wide Association Studies Associated with Backfat Thickness in Landrace and Yorkshire Pigs

Lee YS, Shin D

Although pork quality traits are important commercially, genome-wide association studies (GWASs) have not well considered Landrace and Yorkshire pigs worldwide. Landrace and Yorkshire pigs are important pork-providing breeds. Although quantitative...
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RGISS: Rice (Oryza sativa L. ssp. japonica) Genome Information Service System

Lee D, Seo H, Hahn JH, Kong EB, Park K

  • KMID: 2166285
  • Genomics Inform.
  • 2007 Dec;5(4):194-195.
We have constructed the Rice Genome Information Service System (RGISS), which is an information service system of the Oryza sativa L. ssp. japonica (rice) genome, using the released version of...
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