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Changes in Gastrointestinal Physiology in Obese Patients

Yun SH, Park JK, Shin JE, Diet, Obesity, and Metabolism Research Group of Korean Society of Neurogastroenterology and Motility

Obesity is a prevalent disease with significant morbidity and mortality. It is a state of chronic low-grade inflammation due to excess body fat. Weight homeostasis is maintained through changes in...
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Role of Gut Microbiota-Gut Hormone Axis in the Pathophysiology of Functional Gastrointestinal Disorders

Fukui H, Xu X, Miwa H

  • KMID: 2417381
  • J Neurogastroenterol Motil.
  • 2018 Jul;24(3):367-386.
  • doi: 10.5056/jnm18071
Gut microbiota exert a pivotal influence on various functions including gastrointestinal (GI) motility, metabolism, nutrition, immunity, and the neuroendocrine system in the host. These effects are mediated by not only...
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Regulation of gastrointestinal hormones during laxative activity of gallotannin-enriched extract isolated from Galla Rhois in loperamide-induced constipation of SD rats

Kim JE, Kang MJ, Choi JY, Park JJ, Lee MR, Song BR, Kim HR, Park JW, Choi HJ, Bae SJ, Hwang DY

Regulation of gastrointestinal hormones have been reported in animal models for constipation undergoing laxative therapy when administered herbal products. We undertook to investigate whether the laxative activity of gallotannin-enriched extracts...
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Effect of Nutrient Preload and Food Order on Glucose, Insulin, and Gut Hormones

Bae JH, Cho YM

Postprandial hyperglycemia is associated with the risk of diabetes mellitus, cardiovascular disease, and mortality. Nutrition therapy is an important component of the management of postprandial hyperglycemia. Postprandial glucose levels are...
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Mechanism of Weight Loss and Diabetes Remission after Bariatric/Metabolic Surgery

Cho YM

  • KMID: 2267841
  • Korean J Med.
  • 2013 May;84(5):629-639.
The greatest achievement in the treatment of obesity and diabetes would be the development of bariatric/metabolic surgery. At the beginning, bariatric surgeries were developed to simply reduce body weight in...
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Can Gum Chewing Reduce Postoperative Ileus after Open Abdominal Surgery?

Park SY, Chung M

PURPOSE: Gum chewing activates chephalic-vagal reflex as in food consumption and increases the release of gastrointestinal hormones which are related with gut motility. The objective of this study was to...
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Altered Secretory Pattern of Pancreatic Enzymes and Gastrointestinal Hormones in Streptozotocin-induced Diabetic Rats

Kim MJ, Ryu GR, Yi SY, Min DS, Rhie DJ, Yoon SH, Hahn SJ, Kim MS, Jo YH

  • KMID: 1615198
  • Korean J Physiol Pharmacol.
  • 2002 Dec;6(6):311-317.
This study was performed to investigate the pancreatic exocrine dysfunction in streptozotocin- induced diabetic rats. Changes in pancreatic enzymes secretion and in pancreatic enzymes content were observed. The output and...
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Melatonin Attenuates Noise Stress-induced Gastrointestinal Motility Disorder and Gastric Stress Ulcer: Role of Gastrointestinal Hormones and Oxidative Stress in Rats

Zhang L, Gong JT, Zhang HQ, Song QH, Xu GH, Cai L, Tang XD, Zhang HF, Liu FE, Jia ZS, Zhang HW

  • KMID: 2381251
  • J Neurogastroenterol Motil.
  • 2015 Apr;21(2):189-199.
  • doi: 10.5056/jnm14119
BACKGROUND/AIMS: There are increasing evidences for gastrointestinal motility disorder (GIMD) and gastric stress ulcer induced by noise stress. The present study was to investigate the reversed effect of melatonin on...
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Effects of Intraduodenal Infusions of L-phenylalanine and L-glutamine on Antropyloroduodenal Motility and Plasma Cholecystokinin in Healthy Men

Steinert R, Landrock M, Horowitz M, Feinle-Bisset C

  • KMID: 2433480
  • J Neurogastroenterol Motil.
  • 2015 Jul;21(3):404-413.
  • doi: 10.5056/jnm14143
BACKGROUND/AIMS: Dietary proteins have potent eating-inhibitory and glucose-lowering effects, which may be mediated via effects of amino acids on gastrointestinal hormone and motor function, although little information is available. We...
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Effects of Intraduodenal Infusion of the Bitter Tastant, Quinine, on Antropyloroduodenal Motility, Plasma Cholecystokinin, and Energy Intake in Healthy Men

Bitarafan , Fitzgerald PCE, Little TJ, Meyerhof W, Wu T, Horowitz M, Feinle-Bisset C

  • KMID: 2454640
  • J Neurogastroenterol Motil.
  • 2019 Jul;25(3):413-422.
  • doi: 10.5056/jnm19036
BACKGROUND/AIMS: Nutrient-induced gut hormone release (eg, cholecystokinin [CCK]) and the modulation of gut motility (particularly pyloric stimulation) contribute to the regulation of acute energy intake. Non-caloric bitter compounds, including quinine,...
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The Change of Plasma Ghrelin and Peptide YY3-36 Levels after Meal

Choi SH, Lee S, Kim HH, Jeon TY, Kim HJ

  • KMID: 1513323
  • Korean J Obes.
  • 2007 Mar;16(1):1-5.
BACKGROUND: Ghrelin and Peptide YY3-36 are gastrointestinal hormones related energy homeostasis. We investigated the changes in post-meal plasma ghrelin and PYY3-36 levels in people after meal, simultaneously. METHODS: Nine healthy volunteers...
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Guanylyl cyclase C and guanylin reduce fat droplet accumulation in cattle mesenteric adipose tissue

Yasuda M, Kawabata J, Akieda-Asai S, Nasu T, Date Y

Guanylyl cyclase C (GC-C) is a member of a family of enzymes that metabolize GTP to cGMP and was first identified as a receptor for heat-stable enterotoxin. Guanylin (GNY) has...
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