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Morphology and Distribution of Gap Junction in Horizontal Cells of the Rabbit Retina

Cha J, Kim IB

  • KMID: 2092951
  • Korean J Anat.
  • 2008 Dec;41(4):271-277.
Horizontal cells (HCs) of the mammalian retina are interneurons that provide negative feedback to photoreceptors in the outer plexiform layer (OPL) where the first synapse occurs and contribute to the...
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Ultrastructural Changes of the Rabbit Lens Fiber Cells in Cataract

Cho HT

  • KMID: 2108197
  • J Korean Ophthalmol Soc.
  • 1997 Apr;38(4):593-600.
This study was carried out to investigate the ultrastructural changes of lens fiber cells, length of gap junctions, and distribution of proteoplycans in cataractous lens. The cataract was induced by...
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Role of gap junctions in the endothelium-dependent hyperpolarization of vascular smooth muscle cells

Yamamoto Y, Klemm MF, Hashitani , Lang JR, Soji T, Suzuki H

  • KMID: 1606832
  • Korean J Physiol Pharmacol.
  • 2001 Feb;5(1):1-8.
Hyperpolarization of arterial smooth muscle by acetylcholine is considered to be produced by the release of an unidentified chemical substance, an endothelium-derived hyperpolarizing factor (EDHF). Several chemicals have been proposed as the candidate...
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Effect of Mefloquine, a Gap Junction Blocker, on Circadian Period2 Gene Oscillation in the Mouse Suprachiasmatic Nucleus Ex Vivo

Koo J, Choe HK, Kim HD, Chun SK, Son GH, Kim K

BACKGROUND: In mammals, the master circadian pacemaker is localized in an area of the ventral hypothalamus known as the suprachiasmatic nucleus (SCN). Previous studies have shown that pacemaker neurons in...
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Gap Junction Contributions to the Goldfish Electroretinogram at the Photopic Illumination Level

Kim DY, Jung CS

Understanding how the b-wave of the electroretinogram (ERG) is generated by full-field light stimulation is still a challenge in visual neuroscience. To understand more about the origin of the b-wave,...
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Expression Pattern of Gap Junction Protein, Connexin 26 and 43 in Human Middle Ear Cholesteatomas

Choung YH, Park K, Kang SO, Shin YR, Cho MJ, Yoon YR

  • KMID: 2276545
  • Korean J Otolaryngol-Head Neck Surg.
  • 2006 Jan;49(1):29-34.
BACKGROUND AND OBJECTIVES: A human cholesteatoma in the middle ear is characterized by the presence of a keratinizing epithelium from hyperproliferative properties. It needs intercellular signal exchange through gap junctions...
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Gap junction blockage promotes cadmium-induced apoptosis in BRL 3A derived from Buffalo rat liver cells

Hu D, Zou H, Han T, Xie J, Dai N, Zhuo L, Gu J, Bian J, Yuan Y, Liu X, Liu Z

Gap junctions mediate direct communication between cells; however, toxicological cascade triggered by nonessential metals can abrogate cellular signaling mediated by gap junctions. Although cadmium (Cd) is known to induce apoptosis...
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Antimutagenic and anticarcinogenic effect of methanol extracts of Petasites japonicus Maxim leaves

Kang HG, Jeong SH, Cho JH

The methanol extract from the leaves of Petasites japonicus Maxim (PJ) was studied for its (anti-)mutagenic effect with the SOS chromotest and reverse mutation assay. The (anti-)carcinogenic effects were evaluated...
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Spinal Gap Junction Channels in Neuropathic Pain

Jeon YH, Youn DH

Damage to peripheral nerves or the spinal cord is often accompanied by neuropathic pain, which is a complex, chronic pain state. Increasing evidence indicates that alterations in the expression and...
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Oculodentodigital Dysplasia Presenting as Spastic Paraparesis: The First Genetically Confirmed Korean Case and a Literature Review

Park KW, Ryu HS, Kim J, Chung SJ

Oculodentodigital dysplasia (ODDD) is a rare autosomal dominant inherited disease caused by mutations of the human gap junction alpha 1 gene, which encodes the protein Connexin-43. Patients with ODDD may...
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The Significance of Connexin 26 Expression in Squamous Cell Lesions of the Larynx

Kim SY, Cho SI, Do NY, Lee JH, Kim GH, Lim SC

  • KMID: 2276756
  • Korean J Otolaryngol-Head Neck Surg.
  • 2007 May;50(5):442-447.
BACKGROUND AND OBJECTIVES: Gap junctional intercellular communication (GJIC) is a mechanism for direct cell to cell signalling and is mediated by gap junctions, which consist of transmembrane proteins called connexins...
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Chemical coupling between horizontal cells in the catfish retina

Lee SJ, Jung CS, Bai SH

  • KMID: 2071520
  • Korean J Physiol Pharmacol.
  • 1998 Feb;2(1):21-30.
The effects of GABA and glutamate on the horizontal cells were explored by an intracellular recording method to discern the mechanisms of receptive field formation by chemical coupling in the catfish outer retina....
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Histopathologic Study of the Outer Membrane of Chronic Subdural Hematoma Related to Membrane Permeability

Park YK, Lee KC, Lee HK

  • KMID: 1955163
  • J Korean Neurosurg Soc.
  • 1995 Apr;24(4):444-449.
Permeability of membrane of chronic SDH is a unique characteristic. And various types of attenuation of chronic subdural hematoma(SDH) appearing on computerized tomography(CT) scans are related to the changes occurring...
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Role of Gap Junction in the Regulation of Renin Release and Intracellular Calcium in As 4.1 Cell Line

Han JH, Hong BZ, Kwak YG, Yuan K, Park WH, Kim SZ, Kim SH

  • KMID: 2285333
  • Korean J Physiol Pharmacol.
  • 2007 Jun;11(3):107-112.
Gap junction protein, connexin, is expressed in endothelial cells of vessels, glomerulus, and renin secreting cells of the kidney. The purpose of this study was to investigate the role of...
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The Pharmacological Regulation of Interstitial Cells of Cajal in the Small Intestine

Jun JY

  • KMID: 2307406
  • Korean J Neurogastroenterol Motil.
  • 2009 Dec;15(2):93-99.
It is now known that certain class of interstitial cells of Cajal (ICC) serves as pacemaker cells in the phasic portions of the gastrointestinal (GI) tract. They generate and propagate...
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Immunocytochemical Study on Vimentin Expression in Osteoblasts and Osteocytes of Rat

Ryu SW, Song JY, Park JJ, Yoon JR

  • KMID: 1883449
  • Chonnam Med J.
  • 2004 Dec;40(4):180-185.
The osteoblast and osteocyte processes are filled with densely packed filaments, most of which have been previously shown to be actin microfilaments. However, the appearance of 10 nm diameter filaments...
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A study on the expression of connexin 43 in the experimental tooth movement of rat

Lim JH, Kang KH, Lee JJ, Kim EC, Kim SC

  • KMID: 1923797
  • Korean J Orthod.
  • 2001 Oct;31(5):525-534.
Bone remodeling in response to force requires coordinated actions of osteoblasts, osteoclasts, osteocytes, and periodontal ligament cells. Coordination among these cells may be mediated, in part, by cell-to-cell communication via...
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Influence of Myoendothelial Gap Junction on the Regulation of Vasomotor Tone

Huh J, Ro YJ, Min SW, Kim CS, Kang SS, Jung IY, Park WS, Chung SH, Bahk JH

BACKGROUND: In addition to nitric oxide (NO) and prostacyclin (PGI2), there is another endothelium-derived mechanism of smooth muscle relaxation, which is associated with an endothelium-derived hyperpolarizing factor (EDHF). To assess...
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Preventive Effect of Green Tea Extracts on the Inhibition of Connexin Expression Induced by Carcinogen H2O2

Choi SJ, Choung YH

  • KMID: 2276868
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Apr;51(4):355-362.
BACKGROUND AND OBJECTIVES: Carcinogens result in the impairment of intercellular communication as well as intracellular communication of normal cells. Connexin (Cx) is a main constituent protein of gap junctions that...
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Erythrokeratodermia Variabilis Showing Gradual Disappearance of Erythema

Kim H, Park IH, Kang JN, Seol JE, Sung HS

  • KMID: 1802079
  • Korean J Dermatol.
  • 2014 Apr;52(4):260-263.
Erythrokeratodermia variabilis is an autosomal-dominant inherited disease associated with a mutation in gap junction beta (GJB) 3 and 4. It shows two characteristic features: migratory and irregularly shaped erythematous lesions...
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