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A Bayesian Framework to Optimize Performance of Pre-Hospital Stroke Triage Scales

Goyal M, Ospel JM, Kim BJ, Kashani N, Duvekot MH, Roozenbeek B, Ganesh A

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Reassessing Alberta Stroke Program Early CT Score on Non-Contrast CT Based on Degree and Extent of Ischemia

Ospel JM, Menon BK, Marko M, Mayank A, Ganesh A, Nogueira RG, McTaggart RA, Demchuk AM, Poppe AY, Rempel JL, Joshi M, Almekhlafi MA, Zerna C, Tymianski M, Hill MD, Goyal M, the ESCAPE-NA1 investigators

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Sex and Gender Differences in Stroke and Their Practical Implications in Acute Care

Ospel J, Singh N, Ganesh A, Goyal M

There are several controversies regarding the role of sex and gender in the pathophysiology and management of acute stroke. Assessing the role of sex, i.e., biological/pathophysiological factors, and gender, i.e.,...
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Replacing Alteplase with Tenecteplase: Is the Time Ripe?

Singh N, Menon BK, Dmytriw AA, Regenhardt RW, Hirsch JA, Ganesh A

Thrombolysis for acute ischemic stroke has predominantly been with alteplase for over a quarter of a century. In recent years, with trials showing evidence of higher rates of successful reperfusion,...
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How Do Quantitative Tissue Imaging Outcomes in Acute Ischemic Stroke Relate to Clinical Outcomes?

Ospel JM, Rinkel L, Ganesh A, Demchuk A, Heran M, Sauvageau E, Joshi M, Haussen D, Jayaraman M, Coutts S, Yu A, Puetz V, Iancu D, Bang OY, Tarpley J, Holmin S, Kelly M, Tymianski M, Hill M, Goyal M, the ESCAPE-NA1 Investigators

Background and Purpose Infarct volume and other imaging markers are increasingly used as surrogate measures for clinical outcome in acute ischemic stroke research, but how improvements in these imaging surrogates...
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