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Erectile Dysfunction in Germ Cell Tumor Survivors

Okada K, Fujita K, Fukuhara S, Kiuchi H, Uemura M, Imamura R, Nonomura N

Purpose: Germ cell tumors (GCTs) are the most common malignant neoplasms in adolescents and young adults, and most patients with these tumors can be completely cured. Therefore, maintaining quality of...
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Association between Lymphovascular Invasion and Recurrence in Patients with pT1N+ or pT2–3N0 Gastric Cancer: a Multi-institutional Dataset Analysis

Fujita K, Kanda M, Ito S, Mochizuki , Teramoto H, Ishigure K, Murai T, Asada T, Ishiyama A, Matsushita H, Tanaka C, Kobayashi , Fujiwara M, Murotani K, Kodera Y

PURPOSE: Patients with pathological stage T1N+ or T2–3N0 gastric cancer may experience disease recurrence following curative gastrectomy. However, the current Japanese Gastric Cancer Treatment Guidelines do not recommend postoperative adjuvant...
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Role of Androgen Receptor in Prostate Cancer: A Review

Fujita K, Nonomura N

Androgen receptor (AR) is a steroid receptor transcriptional factor for testosterone and dihydrotestosterone consisting of four main domains, the N-terminal domain, DNA-binding domain, hinge region, and ligand-binding domain. AR plays...
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Long-term stability after multidisciplinary treatment involving maxillary distraction osteogenesis, and sagittal split ramus osteotomy for unilateral cleft lip and palate with severe occlusal collapse and gingival recession: A case report

Kokai S, Fukuyama E, Omura S, Kimizuka S, Yonemitsu , Fujita K, Ono T

In this report, we describe a case involving a 34-year-old woman who showed good treatment outcomes with long-term stability after multidisciplinary treatment for unilateral cleft lip and palate (CLP), maxillary...
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Closed Wedge Distal Femoral Osteotomy with a Polyaxial Locking Plate Designed for the Proximal Tibia: Minimum 5-Year Outcomes

Nakamura R, Fujita K, Omi R, Kuroda K, Takahashi , Ikebuchi K, Nishimura , Katsuki Y

Since distal femoral varus osteotomy (DFO) -specific plates had not been available in Japan before 2015, we performed DFO using a plate for tibia. The purpose of this study was...
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Assessment of the Latent Adverse Events of Antipsychotic Treatment Using a Subjective Questionnaire in Japanese Patients with Schizophrenia

Hatano M, Kamei H, Kato A, Takeuchi I, Hanya M, Uno J, Yamada S, Fujita K, Iwata N

OBJECTIVE: The adverse effects of antipsychotic agents can have a marked influence on medication adherence. In this study, we investigated the adverse events of antipsychotics that are less likely to...
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A Questionnaire-based Study of the Views of Schizophrenia Patients and Psychiatric Healthcare Professionals in Japan about the Side Effects of Clozapine

Takeuchi I, Hanya M, Uno J, Amano Y, Fukai K, Fujita K, Kamei H

OBJECTIVE: It is well documented that clozapine treatment causes agranulocytosis, but it can also induce drowsiness, constipation, and hypersalivation; however, these symptoms are usually less severe. It has been reported...
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Effect of Adenine on Clozapine-induced Neutropenia in Patients with Schizophrenia: A Preliminary Study

Takeuchi I, Kishi T, Hanya M, Uno J, Fujita K, Kamei H

OBJECTIVE: This study examined the utility of adenine for preventing clozapine-induced neutropenia. METHODS: This retrospective study examined the effect of adenine on clozapine-induced neutropenia in patients with treatment-resistant schizophrenia and was...
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Effect of Scopolamine Butylbromide on Clozapine-induced Hypersalivation in Schizophrenic Patients: A Case Series

Takeuchi I, Suzuki T, Kishi T, Kanamori D, Hanya M, Uno J, Fujita K, Kamei H

Clozapine has been demonstrated to be useful for treating refractory schizophrenia. However, hypersalivation occurs in 31.0-97.4% of the patients treated with clozapine. Accordingly, some patients who are disturbed by their...
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Early Effect of Single-dose Sitagliptin Administration on Gastric Emptying: Crossover Study Using the 13C Breath Test

Nonaka T, Sekino Y, Iida H, Yamada E, Ohkubo H, Sakai E, Higurashi , Hosono K, Endo H, Koide T, Takahashi , Fujita K, Yoneda M, Goto A, Kusakabe A, Kobayashi , Gotoh E, Maeda S, Nakajima A, Nosaka C, Inamori M

  • KMID: 2325795
  • J Neurogastroenterol Motil.
  • 2013 Apr;19(2):227-232.
BACKGROUND/AIMS: The gastrointestinal motility effects of endogenous incretin hormones enhanced by dipeptidyl peptidase-IV (DPP-IV) inhibitors have not yet been sufficiently investigated. The aim of this study was to determine whether...
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Effects of Histamine-2 Receptor Antagonists and Proton Pump Inhibitors on the Rate of Gastric Emptying: A Crossover Study Using a Continuous Real-Time 13C Breath Test (BreathID System)

Nonaka T, Kessoku T, Ogawa Y, Imajyo K, Yanagisawa S, Shiba T, Sakaguchi , Atsukawa K, Takahashi , Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo H, Sakamoto Y, Fujita K, Yoneda M, Koide T, Takahashi , Tokoro C, Abe Y, Gotoh E, Maeda S, Nakajima A, Inamori M

  • KMID: 2325819
  • J Neurogastroenterol Motil.
  • 2011 Jul;17(3):287-293.
BACKGROUND/AIMS: The effects of Histamine-2 receptor antagonists and proton pump inhibitors on the gastrointestinal motility have not yet been sufficiently investigated. The aim of this study was to determine the...
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Change of Gastric Emptying With Chewing Gum: Evaluation Using a Continuous Real-Time 13C Breath Test (BreathID System)

Sakamoto Y, Kato S, Sekino Y, Sakai E, Uchiyama T, Iida H, Hosono K, Endo H, Fujita K, Koide T, Takahashi , Yoneda M, Tokoro C, Goto A, Abe Y, Kobayashi , Kubota K, Maeda S, Nakajima A, Inamori M

  • KMID: 2326212
  • J Neurogastroenterol Motil.
  • 2011 Apr;17(2):174-179.
BACKGROUND/AIMS: There are few reports on the correlation between chewing gum and the gastrointestinal functions. But previous report showed use of chewing gum to be an effective method for controlling...
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Mosapride Accelerates the Delayed Gastric Emptying of High-Viscosity Liquids: A Crossover Study Using Continuous Real-Time 13C Breath Test (BreathID System)

Sakamoto Y, Sekino Y, Yamada E, Ohkubo H, Higurashi , Sakai E, Iida H, Hosono K, Endo H, Nonaka T, Ikeda T, Fujita K, Yoneda M, Koide T, Takahashi , Goto A, Abe Y, Gotoh E, Maeda S, Nakajima A, Inamori M

  • KMID: 2325841
  • J Neurogastroenterol Motil.
  • 2011 Oct;17(4):395-401.
BACKGROUND/AIMS: The administration of liquid nutrients to patients is often accompanied by complications such as gastroesophageal reflux. To prevent gastroesophageal reflux, high-viscosity liquid meals are used widely, however, it still...
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