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Coagulation abnormalities and bleeding in pregnancy: an anesthesiologist's perspective

Yoon HJ

During pregnancy, the procoagulant activity increases (manifested by elevation in factor VII, factor VIII, factor X, and fibrinogen levels), while the anticoagulant activity decreases (characterized by reduction in fibrinolysis and...
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Usefulness of Rotational Thromboelastometry as a Mortality Predictor of Hyperfibrinolysis in Patients with Severe Trauma

Kim JS, Wang IJ, Yeom SR, Cho SJ, Kim JH, Seok JP, Lee SH, Bae BG, Min MK

BACKGROUND: Hemorrhage is the major cause of traumatic death and the leading cause of preventable death. Hyperfibrinolysis is associated with trauma severity. Viscoelastic hemostatic assays show complete clot formation dynamics....
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Dry Socket Etiology, Diagnosis, and Clinical Treatment Techniques

Mamoun J

Dry socket, also termed fibrinolytic osteitis or alveolar osteitis, is a complication of tooth exodontia. A dry socket lesion is a post-extraction socket that exhibits exposed bone that is not...
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Long-term clinical outcome of acute myocardial infarction according to the early revascularization method: a comparison of primary percutaneous coronary interventions and fibrinolysis followed by routine invasive treatment

Min HK, Park JY, Choi JW, Ryu SK, Kim S, Song CS, Kim DS, Song CW, Kim SJ, Kim YB

BACKGROUND: This study was conducted to provide a comparison between the clinical outcomes of primary percutaneous coronary intervention (PCI) and that of fibrinolysis followed by routine invasive treatment in ST...
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Methylenetetrahydrofolate Reductase Polymorphisms and Risk of Recurrent Pregnancy Loss: a Case-Control Study

Hwang KR, Choi YM, Kim JJ, Lee SK, Yang KM, Paik EC, Jeong HJ, Jun JK, Yoon SH, Hong MA

The balance between coagulation and fibrinolysis is an essential part in early pregnancy. Mutations in methylenetetrahydrofolate reductase (MTHFR) gene lead to decreased activity of the enzyme and hyperhomocysteinemia, which then...
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Are pulmonary hemostasis and fibrinolysis out of balance in equine chronic pneumopathies?

Barton AK, Wirth C, Bondzio A, Einspanier R, Gehlen H

Clinical examination, bronchoalveolar lavage fluid (BALF) cytology, acute-phase protein, and pulmonary hemostasis and fibrinolysis marker (fibrinogen, serum amyloid A [SAA], and D-dimer) results were compared between control and respiratory disease-affected...
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Management of Blood Loss in Hip Arthroplasty: Korean Hip Society Current Consensus

Song JH, Park JW, Lee YK, Kim IS, Nho JH, Lee KJ, Park KK, Kim Y, Park JH, Han SB

The volume of hip arthroplasty is stiffly increasing because of excellent clinical outcomes, however it has not been shown to decrease the incidence of transfusions due to bleeding related to...
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A Comparison between Mechanical Thrombectomy and Intra-arterial Fibrinolysis in Acute Basilar Artery Occlusion: Single Center Experiences

Jung S, Jung C, Bae YJ, Choi BS, Kim JH, Lee SH, Chang JY, Kim BJ, Han MK, Bae HJ, Kwon BJ, Cha SH

BACKGROUND AND PURPOSE: Recent advances in intra-arterial techniques and thrombectomy devices lead to high rate of recanalization. However, little is known regarding the effect of the evolvement of endovascular revascularization...
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Salvage Therapy from Traumatic Ischemic Finger Necrosis via Prostaglandin E1 Assisted Conservative Treatment: A Case Report

Shin JH, Chang HG, Yang CJ, Ahn J

Prostaglandin E1 (PGE-1) is a potent vasodilator, which also inhibits platelet aggregation, affects the blood flow viscosity, and fibrinolysis. The compound also excerts anti-inflammatory effects by inhibiting the monocyte and...
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Chronic Rhinosinusitis and the Coagulation System

Kim DY, Cho SH, Takabayashi T, Schleimer

Chronic rhinosinusitis (CRS) is one of the most common chronic diseases in adults and severely affects quality of life in patients. Although various etiologic and pathogenic mechanisms of CRS have...
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Spontaneous Arterial Bleeding in Patients with Alcoholic Liver Cirrhosis: a Series of Three Cases

Seon CS, Jo Y, Lee J, Jo YK, Ahn SB, Son B, Cho YK

Spontaneous arterial bleeding has been reported rarely. In a patient consuming heavy amounts of alcohol with alcoholic liver cirrhosis, spontaneous bleeding can be evoked by thrombocytopenia, altered platelet function, and...
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Generation of Proinflammatory Mediator of Intervertebral Disc Cells by Nicotine Stimulation

Seo HY, Yun JH, Kim DY

STUDY DESIGN: Experimental investigation in vitro. OBJECTIVES: To evaluate the relationship between the degeneration of intervertebral disc cells, and low back pain induced by degeneration of intervertebral disc cells and increases...
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Effect of Rivaroxaban on Fibrinolytic Therapy in Massive Pulmonary Embolism: Two Cases

Kim HJ, Koo SM, Ham NS, Kim KU, Uh ST, Kim YK

  • KMID: 2320494
  • Tuberc Respir Dis.
  • 2014 Mar;76(3):127-130.
The risk of dying from a pulmonary embolism (PE) is estimated to be about 30% if inotropic support is required and no cardiopulmonary arrest occurs. Fibrinolysis in massive PE is...
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Frameless Stereotactic Aspiration for Spontaneous Intracerebral Hemorrhage and Subsequent Fibrinolysis Using Urokinase

Chang YH, Hwang SK

OBJECTIVES: The optimal management of patients with spontaneous intracerebral hemorrhage (ICH) remains controversial. The aim of this study was to evaluate technical results and clinical outcomes of frameless stereotactic aspiration...
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Clinical Marker of Platelet Hyperreactivity in Diabetes Mellitus

Kim JH, Bae HY, Kim SY

Atherothrombotic complications are important causes of morbidity and mortality in diabetic patients. Diabetes has been considered to be a prothrombotic status. Several factors contribute to the prothrombotic condition, such as...
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Acute Vertebral Artery Origin Occlusion Leading to Basilar Artery Thrombosis Successfully Treated by Angioplasty with Stenting and Intracranial Fibrinolysis

Matsubara , Miyachi S, Kojima T, Nakai Y

There are few reports describing stroke due to the acute occlusion of the vertebral artery (VA) origin successfully treated by endovascularily. The authors report a case of 78-year-old man suffering...
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A Case of Spontaneous Remission of Acute Pulmonary Embolism

Lee JJ, Lee MJ, Park H, Zeon SJ, Lim YM, Song SH, Na DJ, Kim EJ

  • KMID: 2319750
  • Tuberc Respir Dis.
  • 2012 Feb;72(2):232-235.
Acute pulmonary embolism (PE) ranges from asymptomatic to often fatal, incidentally discovered emboli to massive embolism causing immediate death. Acute PE may occur rapidly and unpredictably and may be difficult...
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Floating Thrombus in the Ascending Aorta of the Patient with Systemic Sclerosis: A case report

Lee S, Cho JW, Kwon OC

  • KMID: 2063115
  • Korean J Thorac Cardiovasc Surg.
  • 2011 Feb;44(1):72-75.
Aortic thrombi are important because it can cause the central and peripheral embolizations. Aortic thrombi can occur anywhere in the aorta but extremely rare in ascending aorta without atherosclerosis, aneurysm,...
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Elevated levels of activated and inactivated thrombin-activatable fibrinolysis inhibitor in patients with sepsis

Park R, Song J, An SS

BACKGROUND: In sepsis, large scale inflammatory responses can cause extensive collateral damage to the vasculature, because both coagulation and fibrinolysis are activated unevenly. Thrombin-activatable fibrinolysis inhibitor (TAFI) plays a role...
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Comparison of perioperative thromboelastography between open and laparoscopic colorectal surgery

Cho EJ, Lee J, Park CS

  • KMID: 1803593
  • Anesth Pain Med.
  • 2010 Oct;5(4):365-371.
BACKGROUND: Laparoscopic surgery may affect the coagulation system in several ways. The purpose of this study was to compare the hemostatic changes between open and laparoscopic colorectal surgery by using...
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