- Expression of aquaporin-5 and its regulation in skeletal muscle cells
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Hwang SM, Lee RH, Song JM, Yoon S, Kim YS, Lee SJ, Kang SK, Jung JS
- KMID: 1093600
- Exp Mol Med.
- 2002 Mar;34(1):69-74.
The aquaporins constitute a family of homologous intrinsic membrane proteins that function as highly selective water channels and are highly expressed in tissues where rapid water movement across the cell... -
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- Characterization of cis-acting elements in the rat ATP citrate-lyase gene promoter
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Moon YA, Park SW, Kim KS
- KMID: 1093599
- Exp Mol Med.
- 2002 Mar;34(1):60-68.
The cis-acting element in the promoter of the rat ATP-citrate lyase (ACL) and transcription factors which interact with these elements were determined. Six Sp1 binding sites and CAAT box exist... -
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- Differential modulation of zinc-stimulated p21(Cip/WAF1) and cyclin D1 induction by inhibition of PI3 kinase in HT-29 colorectal cancer cells
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Oh SY, Park KS, Kim AJ, Choi KY
- KMID: 1093594
- Exp Mol Med.
- 2002 Mar;34(1):27-31.
Activation of the extra cellular signal regulated kinase (ERK) pathway is involved in both proliferation and growth arrest of cells depending on intensity and duration of stimuli. In this study,... -
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- Biomedical significance of endothelial cell specific growth factor, angiopoietin
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Koh GY, Kim I, Kwak HJ, Yun MJ, Leem JC
- KMID: 1093591
- Exp Mol Med.
- 2002 Mar;34(1):1-11.
Until recently, vascular endothelial growth factor (VEGF) was the only growth factor proven to be specific and critical for blood vessel formation. Other long-known factors, such as the fibroblast growth... -
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- Effects of chlorinated aliphatic hydrocarbons on the fidelity of cell division in human CYP2E1 expressing cells
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Kim A, Parry EM, Parry JM
- KMID: 1093602
- Exp Mol Med.
- 2002 Mar;34(1):83-89.
Chlorinated organic chemicals are widely used in industry and are present in the environment. Five chlorinated aliphatic hydrocarbons, namely 1-2-dichloroethane, 1,1,2-trichloroethane, trichloroethylene, 2,3-dichlorobutane and 1-chlorohexane were investigated to determine their... -
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- The functional domains of dopamine transporter for cocaine analog, CFT binding
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Lee SH, Chang MY, Jeon DJ, Oh DY, Son H, Lee CH, Lee YS, Lee YS
- KMID: 1093603
- Exp Mol Med.
- 2002 Mar;34(1):90-94.
Cocaine analogue, CFT (2beta-carbomethoxy-3beta-(4-fluorophenyl) tropane) binding to dopamine transporter (DAT) in different species is quite heterogeneous. CFT is scarcely detected in bovine DAT whereas it is conspicuous in humans. To... -
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- Expression of integrins, cyclooxygenases and matrix metalloproteinases in three-dimensional human endometrial cell culture system
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Yang H, Han S, Kim H, Choi YM, Hwang KJ, Kwon HC, Kim SK, Cho DJ
- KMID: 1093601
- Exp Mol Med.
- 2002 Mar;34(1):75-82.
The objective of this investigation was to establish a three-dimensionally cultured human endometrium which could be used as a tissue model for the mechanism study of implantation in vitro. By... -
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- D4-GDI is cleaved by caspase-3 during daunorubicin-induced apoptosis in HL-60 cells
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Kwon KB, Park EK, Ryu DG, Park BH
- KMID: 1093595
- Exp Mol Med.
- 2002 Mar;34(1):32-37.
Daunorubicin, an anti-cancer drug, is known to induce apoptosis in HL-60 cells in a dose-dependent manner through the activation of caspase-3 (CPP32). Caspase-3 selective inhibitor, Ac-DEVD-CHO, prevented both the activation... -
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- Enhanced expression of neuronal nitric oxide synthase and phospholipase C-gamma1 in regenerating murine neuronal cells by pulsed electromagnetic field
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Kim SS, Shin HJ, Eom DW, Huh JR, Woo Y, Kim H, Ryu SH, Suh PG, Kim MJ, Kim JY, Koo TW, Cho YH, Chung SM
- KMID: 1093598
- Exp Mol Med.
- 2002 Mar;34(1):53-59.
Pulsed electromagnetic field (PEMF) has been shown to improve the rate of peripheral nerve regeneration. In the present study we investigated the expression of neuronal nitric oxide synthase (nNOS) and... -
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- The p38 mitogen-activated protein kinase is involved in stress-induced phospholipase D activation in vascular smooth muscle cells
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Min DS, Shin EY, Kim EG
- KMID: 1093596
- Exp Mol Med.
- 2002 Mar;34(1):38-46.
Oxidative stress has been implicated in mediation of vascular disorders. Earlier study showed that the exposure of vascular smooth muscle cells (VSMC) to pervanadate (hydrogen peroxide plus orthovanadate) resulted in... -
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- Alterations of HLA class I and class II antigen expressions in borderline, invasive and metastatic ovarian cancers
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Lee YS, Kim TE, Kim BK, Park YG, Kim GM, Jee SB, Ryu KS, Kim IK, Kim JW
- KMID: 1093593
- Exp Mol Med.
- 2002 Mar;34(1):18-26.
In an effort to understand whether HLA class I and II plays any role in the process of tumorigenesis and metastasis, we have immunohistochemically examined expression of HLA class I... -
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- Aspartate modulates the ethanol-induced oxidative stress and glutathione utilizing enzymes in rat testes.
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Oh SI, Lee MS, Kim CI, Song KY, Park SC
- KMID: 1093597
- Exp Mol Med.
- 2002 Mar;34(1):47-52.
In order to develop a preventive strategy against ethanol-induced oxidative damages on various tissues and organs, we have examined the protective effect of aspartate on the pathogenesis of testes in... -
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- The stimulatory effect of IL-1beta on the insulin secretion of rat pancreatic islet is not related with iNOS pathway
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Jeong IK, Oh SH, Chung JH, Min YK, Lee MS, Lee MK, Kim KW
- KMID: 1093592
- Exp Mol Med.
- 2002 Mar;34(1):12-17.
Interleukin 1 (IL-1) is a pleiotropic cytokine with the potential to destroy pancreatic beta-cells, and thought to be involved in the pathogenesis of type I diabetes mellitus. Expression of inducible... -
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