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The Role of Superantigen in Nasal Polypogenesis

Yoon BK, Kim DW

  • KMID: 2132085
  • J Rhinol.
  • 2013 Nov;20(2):88-95.
Superantigens are potent immunostimulatory exotoxins well known to be produced by Staphylococcus aureus (S. aureus). These exotoxins have capacity to act as superantigens by binding with the variable beta(Vbeta) region...
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The Effect of Skin-colonizing Staphylococcus aureus and Its Exotoxins on Childhood Atopic Dermatitis

Kim YH, Lee ES, Kim JS, Kim MJ, Jung JA, Yang S, Hwang IT, Lee HR

  • KMID: 2314415
  • Pediatr Allergy Respir Dis.
  • 2006 Jun;16(2):162-170.
PURPOSE: Staphylococcus aureus and its exotoxins have been regarded as having an influence on atopic dermatitis(AD). We aimed to examine the prevalence of S. aureus in the AD lesion, the...
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Detection of Staphylococcus Aureus Exotoxins(SEA, TSST-1) in Nasal Polyp with Chronic Rhinosinusitis Patients

Ha J, Gang I, Kim ST

BACKGROUND AND OBJECTIVES: Staphylococcus aureus (S. aureus) exotoxins have been implicated in the pathogenesis of chronic sinusitis with nasal polyp. The aim of this study was to identify the interplay...
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A Study on the Evaluation of the Staphylococcal Exotoxins and Staphylococcal Enterotoxin A-specific IgE Antibody in Childhood Atopic Dermatitis

Yim YS, Park CW, Lee CH, Song WK

  • KMID: 2250814
  • Korean J Dermatol.
  • 2002 Jun;40(6):607-615.
BACKGROUND: The skin of patients with atopic dermatitis (AD) exhibits a striking susceptibility to colonization with Staphylococcus aureus (S. aureus). Superantigenic exotoxins produced by S. aureus and their specific IgE...
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Two Cases of Cellulitis on the Saphenous Venectomy Scar after a Coronary Artery Bypass Graft

Seo JJ, Kim SJ, Lee SC, Chun IK, Won YH

  • KMID: 2086039
  • Korean J Dermatol.
  • 1998 Feb;36(1):177-180.
We report two cases of cellulitis on the saphenous venectomy scar which developed after a coronary artery bypass graft(CABG). A 68-year-old male and a 62-year-old female developed acute cellulitis in...
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Genotype Analysis of Pyrogenic Exotoxin and emm Genes of Streptococcus pyogenes Clinical Isolates

Lee YH, Hwang KJ, Lee KJ, Bae SM, Kim KS

  • KMID: 2054970
  • J Bacteriol Virol.
  • 2003 Dec;33(4):277-283.
A variety of proteins produced by Streptococcus pyogenes contribute to the virulence of the pathogen. Among the proteins, the M protein and streptococcal pyrogenic exotoxins (Spe) are considered the major...
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A Case of Clostridium sordellii Bacteremia in a Patient with Osteosarcoma

Moon SY, Lee SS, Won JE, Kim Y, Kim HJ, Kim HS, Kang HJ, Chung DR

  • KMID: 2285084
  • Infect Chemother.
  • 2006 Feb;38(1):51-54.
Clostridium sordellii is a gram-positive spore forming anaerobic bacillus, rarely encountered in human infection. It produces several exotoxins which contribute to myonecrosis, pulmonary infection, obstetric infection and bacteremia. C. sordellii...
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THE VARIOUS ROLE OF LOCAL INJECTION OF BOTULINUM A EXOTOXIN

Lee YH, Choi HC, Hong JJ

  • KMID: 2117623
  • J Korean Soc Aesthetic Plast Surg.
  • 1999 Sep;5(2):377-389.
Botulium toxin A has been used therapeutically in humans for over 20 years for a variety of medical indications. Some wrinkle and unsightly facial expressions are due to hyperkinetic muscle....
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Vibrio vulnificus Hemolysin Is Easily Inactivated in Spite of Being Produced at High Levels in Cirrhotic Ascites by a fur Mutation

Kim CM, Kim SC, Shin SH

Vibrio vulnificus produces Hemolysin/cytolysin (VvhA), which is one of the most potent exotoxins capable of killing mice at submicrogram levels. However, V. vulnificus growth and vvhA expression are severely repressed...
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A Comparison Study of the Staphylococcal Exotoxins and Staphylococcal Enterotoxin A-specific IgE Antibody between Childhood and Adulthood Atopic Dermatitis

Kim HW, Park CW, Lee CH, Song WK

BACKGROUND: The skin of patients with atopic dermatitis (AD) exhibits a striking susceptibility to colonization with Staphylococcus aureus (S. aureus). Superantigens produced by S. aureus and their specific IgE antibodies...
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A Fatal Case of Infective Endocarditis Caused by Community-Associated Methicillin-Resistant Staphylococcus aureus ST72 in Korea

Choi SH, Chung JW

The advent of community-associated methicillin-resistant Staphylococcus aureus (CA-MRSA) has been a worldwide threat to public health for the past decade. We report a fatal case of infective endocarditis caused by...
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Streptococcal Toxic Shock Syndrome Associated with Intrauterine Fetal Death: A Case Report

Lee SY, Lee JS, Lee MA, Chung WS, Kim SJ

  • KMID: 2425663
  • Korean J Clin Microbiol.
  • 1998 Sep;1(1):109-112.
The group A streptococcus is capable of producing exotoxins that have been linked to a toxic shock-like syndrome. Streptococcal toxic shock syndrome is a rapidly progressive associated with injury to...
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A Two Component Signal Transduction System Required for the Virulence of Vibrio vulnificus

Jin YS, Kim YR, Rhee JH

  • KMID: 1579123
  • J Bacteriol Virol.
  • 2004 Dec;34(4):291-301.
Vibrio vulnificus is an estuarine bacterium that opportunistically infects humans with underlying hepatic diseases, heavy alcohol drinking habits, and other immunocompromised conditions. A locus in the V. vulnificus genome was...
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The Correlation Study between the Specific IgE for Staphylococcus Aureus Exotoxin and Nasal Mucus Culture in Allergic Rhinitis

Yoon JH, Kim SY, Gang IG, Kim ST

  • KMID: 2276847
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2008 Feb;51(2):148-152.
BACKGROUND AND OBJECTIVES: There is a reported association between the increased levels of specific IgE and Staphylococcus aureus exotoxins (SE) and eosinophilic inflammation in nasal polyp tissue. However, the role...
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Development and Utilization of a Mouse Model of Nasal Polyps

Kim SW, Jeon SY, Kim DW

Systemic corticosteroids currently represent the most effective treatment for chronic rhinosinusitis with nasal polyps (CRSwNP), but their long-term use is constrained due to their detrimental side effects. Until recently, development...
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The Correlation Study between the Specific IgE for Staphylococcus Aureus Exotoxin and Nasal Mucus Culture in Chronic Rhinosinusitis with Nasal Polyposis

Yoon JH, Ha JS, Gang IG, Kim ST, Seo YH

  • KMID: 1922225
  • Korean J Otorhinolaryngol-Head Neck Surg.
  • 2007 Jul;50(7):596-601.
BACKGROUND AND OBJECTIVES: Staphylococcus aureus (S. aureus) exotoxins (SE) have been implicated in the pathogenesis of chronic sinusitis with nasal polyposis (CRSwNP). The aim of this study was to identify...
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Role of Staphylococcus Aureus Exotoxins in Chronic Rhinosinusitis with Nasal Polyp

Park YK, Seo ST, Kim EH, Kim DH, Choi JW, Kim YM, Rha KS

BACKGROUND AND OBJECTIVES: Staphylococcal exotoxins (SEs) have been implicated in the pathogenesis of chronic rhinosinusitis with nasal polyp (CRSwNP). In the current study, we determined the prevalence of specific immunoglobulin...
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Effect of Salinity, Temperature, and Glucose on the Production of Vibrio vulnificus Hemolysin

Kim HS, Shin SH, Park HR, Lee SE, Kim CM, Kim SY, Kim YR, Lee HC, Chung SS, Rhee JH

  • KMID: 2054958
  • J Bacteriol Virol.
  • 2002 Dec;32(4):355-366.
Among the exotoxins produced by V. vulnificus, hemolysin (HS) has been reported to be the most potent one. To investigate the factors up- or down-regulating HS production in the context...
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Correlation Between the Prevalence of Superantigenic Toxin Genes and Coagulase Serotypes of Staphylococcus aureus Isolates

Kim YG, Lee HS, Kang SK, Chang KS, Hwang SM

A heterogenic group of staphylococcal exotoxins, including staphylococcal superantigenic toxins, enterotoxin (SE), toxic shock syndrome toxin-1 (TSST-1), and coagulase are the most important virulence factors of Staphylococcus aureus. We analyzed...
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Histopathologic study on the Toxicity of Cytolysin Produced by Vibrio vulnificus

Song CH, Park JW, Kim DI, Cha SH, Kim HT, Lee MS, Kim HR, Park SD

  • KMID: 2092647
  • Korean J Anat.
  • 1998 Feb;31(1):127-136.
Vibrio vulnificus is an estuarine bacterium which causes septicemia and serious wound infection. But the pathogenesis of Vibrio vulnificus infection is unknown. Among the exotoxins secreted by Vibrio vulnificus, cytolysin...
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