- PMA-induced up-regulation of MMP-9 is regulated by a PKCalpha-NF-kappaB cascade in human lung epithelial cells
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Shin YH, Yoon SH, Choe EY, Cho SH, Woo CH, Rho JY, Kim JH
- KMID: 1103685
- Exp Mol Med.
- 2007 Feb;39(1):97-105.
Expression of matrix metalloproteinase-9 (MMP-9) is associated with airway remodeling and tissue injury in asthma. However, little is known about how MMP-9 is up-regulated in airway epithelial cells. In this... -
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- Selectively Decreased Expression of Peroxiredoxins Induced by Silica in Pulmonary Epithelial Cells
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Lee HL, Kim YS, Park JH, Chung WY, Lee KS, Oh YJ, Sheen SS, Park KJ, Hwang SC
- KMID: 1717945
- Korean J Intern Med.
- 2009 Sep;24(3):220-226.
- doi: 10.3904/kjim.2009.24.3.220
BACKGROUND/AIMS: Peroxiredoxin (Prx) belongs to a ubiquitous family of antioxidant enzymes that regulates many cellular processes through intracellular oxidative signal transduction pathways. Silica-induced lung damage involves reactive oxygen species (ROS)... -
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- Sulforaphane Induces Antioxidative and Antiproliferative Responses by Generating Reactive Oxygen Species in Human Bronchial Epithelial BEAS-2B Cells
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Lee YJ, Lee SH
- KMID: 1123448
- J Korean Med Sci.
- 2011 Nov;26(11):1474-1482.
- doi: 10.3346/jkms.2011.26.11.1474
Sulforaphane (SFN) is a naturally occurring compound which is known to induce the phase II antioxidant genes via Nrf2 activation, although the underlying mechanism has not been fully elucidated. In... -
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- The Toxicity of Nonsteroidal Anti-inflammatory Eye Drops against Human Corneal Epithelial Cells in Vitro
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Lee JS, Kim YH, Park YM
- KMID: 2359972
- J Korean Med Sci.
- 2015 Dec;30(12):1856-1864.
- doi: 10.3346/jkms.2015.30.12.1856
This study investigated the toxicity of commercial non-steroid anti-inflammatory drug (NSAID) eye solutions against corneal epithelial cells in vitro. The biologic effects of 1/100-, 1/50-, and 1/10-diluted bromfenac sodium, pranoprofen,... -
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- Epigallocatechin-3-gallate Suppresses Galactose-alpha1,4-galactose-beta1,4-glucose Ceramide Expression in TNF-alpha Stimulated Human Intestinal Epithelial Cells Through Inhibition of MAPKs and NF-kappa B
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Moon DO, Choi SR, Lee CM, Kim GY, Lee HJ, Park YM
- KMID: 1712731
- J Korean Med Sci.
- 2005 Aug;20(4):548-554.
- doi: 10.3346/jkms.2005.20.4.548
Intestinal epithelial cells (IECs) have been known to produce galactose-alpha1,4-galactose-beta1,4-glucose ceramide (Gb3) that play an important role in the mucosal immune response. The regulation of Gb3 is important to prevent... -
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