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Environments of ethidium binding to allosteric Dna: II. Accessibility, mobility and mode of binding

Suh DC

  • KMID: 755100
  • Exp Mol Med.
  • 2000 Dec;32(4):204-209.
DNA binding compounds were previously shown to bind to the right-handed DNA forms and hybrid B-Z forms in a highly cooperative manner and indicate that structural specificity plays...
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Discrepancy in Genotyping of Apolipoprotein E between Allele-Specific PCR and Fluorescence Resonance Energy Transfer or Sequencing

Park CH, Lee ST, Ki CS, Kim JW

The human apolipoprotein E (APOE) gene contains several single-nucleotide polymorphisms (SNPs) that are distributed across the gene. The genotype of the APOE gene has important implications as a risk factor...
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Let Clinicians Classify Emergency Patients

Chung BS

No abstract available.
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Basics of particle therapy I: physics

Park SH, Kang JO

With the advance of modern radiation therapy technique, radiation dose conformation and dose distribution have improved dramatically. However, the progress does not completely fulfill the goal of cancer treatment such...
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Let us not discard a preexisting epidural catheter for intrapartum cesarean section yet!

Bhalotra A

No abstract available.
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The health effects of low-dose radiation exposure

Do KH

Low dose radiation has been defined as doses in the range under 100 mSv of low linear energy transfer (low-LET) radiation. There are two sources of ionizing radiation: natural and...
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Alpha-emitting Radioisotopes Production for Radioimmunotherapy

Chun KS

  • KMID: 1512509
  • Nucl Med Mol Imaging.
  • 2007 Feb;41(1):1-8.
This review discusses the production of alpha-particle-emitting radionuclides in radioimmunotherapy. Radioimmunotherapy labeled with alpha-particle is expected to be very useful for the treatment of monocellular cancer (e.g. leukemia) and micrometastasis...
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Beta Dosimetry in Intraperitoneal Administration of 166Ho-chitosan Complex

Kim EH, Lim SM, Park KB

  • KMID: 2256959
  • Korean J Nucl Med.
  • 1998 Feb;32(1):99-108.
Intraperitoneal adminstration of radioisotopes is suggested to treat the metastatic ovarian cancer in the pertioneal cavity. Administering beta-emitting radioisotopes into the pertioneal cavity allows the maximum energy delivery to the...
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Neutron therapy for prostatic cancer

Lim YS, Lim MS, Moon HK, Lee KH, Ahn HJ, Yoo SY

  • KMID: 2289389
  • Korean J Urol.
  • 1992 Dec;33(6):979-984.
The neutron beam has higher relative biological effectiveness (RBE) than conventional X or gamma ray because it is densely ionizing radiation which is presented by high linear energy transfer (LET)....
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Relative biological effectiveness of fast neutrons for apoptosis in mouse hair follicles

Lee HJ, Kim SH

This study compared the effects of high linear energy transfer (LET) fast neutrons on the induction of apoptosis in the hair follicles of ICR mice with those of low LET...
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Clinical Evaluation of BDProbeTec ET Direct TB Assay for Detection of Mycobacterium tuberculosis Complex in Respiratory and Non-Respiratory Specimens

Kim SY, Park YJ, Kim BK

  • KMID: 2089688
  • Korean J Clin Pathol.
  • 2001 Dec;21(6):512-519.
BACKGROUND: Recently developed BDProbeTec ET direct TB assay (BDET; Becton Dickinson, Sparks, MD, USA) uses strand displacement amplification in which DNA segments of the IS6110 are amplified and detected by...
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The Usefulness of the New ADAMTS-13 Activity Assay using a Fluorescence-quenching Substrate for the Diagnosis of Thrombotic Thrombocytopenic Purpura

Jang MJ, Oh SY, Chong SY, Kang MS, Oh D

BACKGROUND: Ever since medical professionals have recognized the important role of ADAMTS-13 in the pathogenesis of TTP, several methods to diagnosis the activity of ADAMTS-13 in the plasma of TTP...
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Finger-tip Reattachment

Kim SS, Moon ES

Recent advance in the field of microvacular surgery has popularized the reattachment of severed digit, with increasing success rate and improving functional regain. Reattachment surgery was performed in six digits,...
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An Evaluation on the Effect of Psychoanalysis: Psychological Aspect

Park MC

  • KMID: 2051186
  • Psychoanalysis.
  • 2010 Apr;21(1):3-7.
Can psychoanalysis ever demonstrate its effectiveness, let alone cost-effectiveness? Although there are some empirical evidences showing the efficacy of psychoanalysis and dynamic psychotherapy, the nature of such treatments makes it...
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A Comparative Study of Apolipoprotein E Genotyping: INNO-LiPA ApoE Kit, Allelic Discrimination with LightCycler, and BioCore ApoE Kit

Kim IS, Kim HJ, Ki CS, Kim JW

  • KMID: 2239057
  • Korean J Lab Med.
  • 2004 Aug;24(4):255-260.
BACKGROUND: Apolipoprotein E (apoE) polymorphism is associated with the risk and the time of onset of Alzheimer's disease and the risk of developing cardiovascular disease. Therefore, much inter-est in apoE...
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A Novel, Potent, Small Molecule AKT Inhibitor Exhibits Efficacy against Lung Cancer Cells In Vitro

Dinavahi S, Prasanna R, Dharmarajan S, Perumal Y, Viswanadha S

PURPOSE: Anomalies of Akt regulation, including overexpression in lung cancer, impart resistance to conventional chemotherapy and radiation, thereby implicating this kinase as a therapeutic intervention point. A novel scaffold of...
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Decreasing Effect of Lidocaine.HCl on the Thickness of the Neuronal and Model Membrane

Park SM, Park JS, Kim JH, Baek JH, Yoon TG, Lee DK, Ryu WH, Chung IK, Sohn UD, Jang HO, Yun I

This study examined the mechanism of action of a local anesthetic, lidocaine.HCl. Energy transfer between the surface fluorescent probe, 1-anilinonaphthalene-8-sulfonic acid, and the hydrophobic fluorescent probe, 1,3-di(1-pyrenyl) propane, was used...
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Clinical Significance of von Willebrand Factor-Cleaving Protease (ADAMTS13) Deficiency in Patients with Sepsis-Induced Disseminated Intravascular Coagulation

Kim YK, Lee J, Lee KA, Kwon HU

BACKGROUND: Deficiency of von Willebrand factor-cleaving protease, a disintegrin-like and metalloprotease with thrombospondin type 1 motif 13 (ADAMTS13), is thought to be responsible for platelet aggregation and microthrombi formation, which...
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Molecular Optical Imaging in Neuroscience

Kim DE

  • KMID: 1572306
  • J Korean Neurol Assoc.
  • 2006 Apr;24(2):101-105.
Molecular imaging is leading an important role in the era of molecular medicine. Optical imaging, a rising star in the filed of molecular imaging, largely consists of bioluminescent imaging and...
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Educational Training for Residents in Geriatric Psychiatry

Lee MS

  • KMID: 2137462
  • J Korean Geriatr Psychiatry.
  • 2000 Dec;4(2):119-128.
Recently, the effective and systematic education for residents in geriatric psy-chaitry has been receiving needed attention and interests. However, in Korea, the position of the education in geriatric psychaitry is...
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