- Association of Polymorphic Regulatory Region of TIGR Gene with Glaucoma
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Koo HJ, Son S, Kee C
- KMID: 2205978
- J Korean Ophthalmol Soc.
- 2001 Mar;42(3):519-526.
PURPOSE: To identify the polymorphism in the regulatory region of trabecular meshwork inducible glucocorticoid response(TIGR) gene and evaluate the association of it with glaucoma. METHODS: 5'regulatory region of TIGR gene... -
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- Nuclear Factors Bind to the Specific Sites in Promoter Region of Human YB-1 Gene
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Kim YR, Han SW, Ryu PY, Kim KK, Ahn BW, Shin BA
- KMID: 2172429
- Chonnam Med J.
- 2001 Mar;37(1):7-12.
This study was designed to identify the presence of the nuclear factors binding to promoter region of human YB-1 gene and determine their specific binding sites. Nuclear extracts were prepared... -
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- OPG Inhibits PMMA Induced Osteoclastogenesis and NF-kappaB Activation in Osteoclast Precursor Cells
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Kim YS, Choi NY, Kwon SY, Ok JH, Han SK
- KMID: 2199113
- J Korean Orthop Res Soc.
- 2005 Oct;8(2):101-110.
PURPOSE: We investigate the effect of osteoprotegerin (OPG) on activation of osteoclastogenesis and NF-kappaB activation by PMMA (Polymethyl methacrylate) particles in osteoclast precursor cells. MATERIALS AND METHODS: Osteoclast precursor cells (CSF-1... -
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- Activation of Transcription Factor NF-kappaB and c-Jun/AP-1 by Various Compositions of Particles in Osteoclast Precursor Cells
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Kim YS, Kwon SY, Han SK, Kwon JY, Choi NY
- KMID: 2162629
- J Korean Hip Soc.
- 2008 Sep;20(3):209-214.
- doi: 10.5371/jkhs.2008.20.3.209
PURPOSE: This study was performed in order to investigate the effects of various particle preparations on NF-kappaB and c-Jun/AP-1 activity in osteoclast precursor cells. MATERIALS AND METHODS: Osteoclast precursor cells isolated... -
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- Study on the Mechanism of Neutrophil Adhesion to Retinal Capillary Endothelial Cells under High Glucose Condition
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Son SM, Lee YS, Lee CW, Yoo SD, Kim IJ, Kim YK
- KMID: 2010068
- J Korean Diabetes Assoc.
- 2001 Feb;25(1):35-49.
BACKGROUND: Diabetic retinopathy is a leading cause of adult vision loss and blindness. Much of the retinal damage that characterizes the disease results from retinal vascular leakage and occlusion. Capillary... -
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- CYP1A2 polymorphism and theophylline clearance in Korean non-smoking asthmatics
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Yim EY, Kang HR, Jung JW, Sohn SW, Cho SH
- KMID: 2397300
- Asia Pac Allergy.
- 2013 Oct;3(4):231-240.
- doi: 10.5415/apallergy.2013.3.4.231
BACKGROUND: Theophylline is mainly metabolized by cytochrome P450 (CYP) 1A2 and CYP2E1 which show inter-individual variations. However, the underlying mechanism remains unknown in humans. We investigated the relationship between differences... -
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- Upregulation of IP-10(CXCL10) mRNA Expression by Interleukin-18
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Kim HY, Kim HS
- KMID: 2320155
- Yeungnam Univ J Med.
- 2007 Jun;24(1):67-78.
BACKGROUND: Interleukin-18 (IL-18) is one of the principal inducers of interferon-gamma (IFN-gamma) in lymphocytes. MATERIALS AND METHODS: The effect of IL-18 on the expression of chemokine IP-10(CXCL10) mRNA in C57BL/6 mouse... -
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- CCAAT-binding Transcription Factor(CTF) Proteins Required for the Transcriptional Stimulation by Thyroid Hormone in GH4C1 Cells
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Park HY, Hong YS
- KMID: 2078825
- Ewha Med J.
- 1995 Dec;18(4):309-313.
- doi: 10.12771/emj.1995.18.4.309
CAAT-binding transcription factor(CTF) proteins are implicated in the expression of multipleforms and are probably identical to nuclear facfor-1(NF-1). In herpes simplex virus thymidinekinase gene, CTF is required not only to... -
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- Isolation of a Partial Human cDNA Encoding a Factor Binding to the Perfect Palindrome of Enhancer A of HLA Class I Promoter, Homologous to NF-kB2
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Park JH, Lee TJ, Kim SJ
- KMID: 1551643
- J Korean Soc Microbiol.
- 1998 Jun;33(3):295-306.
Genes encoding sequence-specific DNA binding proteins have been isolated by screening cDNA libraries constructed in rgt11 expression vector with recognition site DNAs. We isolated a rgt11 recombinant human cDNA clone,... -
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- Activation of Macrophage by Polysaccharide Isolated from Salicornia herbacea L.
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Im JS, Lee SK, Chang IY, Ha HC, Lim Y, Kim HY, Park KH, Yoon SP
- KMID: 1512979
- Korean J Phys Anthropol.
- 2006 Jun;19(2):117-124.
Salicornia herbacea L. is one of the halophytes that can grow in salt marshes, or salt fields along the seashores in Korea. The objective of this study is to investigate... -
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- Reversal of Immunogenicity in Pediatric Inflammatory Bowel Disease Patients Receiving Anti-Tumor Necrosis Factor Medications
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Kang E, Khalili A, Splawski J, Sferra TJ, Moses J
- KMID: 2421996
- Pediatr Gastroenterol Hepatol Nutr.
- 2018 Oct;21(4):329-335.
- doi: 10.5223/pghn.2018.21.4.329
Loss of response to anti-tumor necrosis factor (anti-TNF) agents in the treatment of inflammatory bowel disease (IBD) is a major consideration to maintain sustained response. Reversal of immunogenicity can re-establish... -
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- Effects of Ultraviolet A and B Irradiation on the Transcriptional Regulation of Stromelysin-1 Gene in Human Fibroblast Cultures
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Kim BC, Park JH, Lee KS
- KMID: 2383028
- Ann Dermatol.
- 1999 Oct;11(4):225-231.
- doi: 10.5021/ad.1999.11.4.225
BACKGROUND: Sun exposure and therapeutic irradiation have been shown to induce alterations in extracellular matrix (ECM) proteins, including elastin, glycosaminoglycan and collagens. The integrity of the connective tissue mainly depends... -
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- LIGHT is Expressed in Foam Cells and Involved in Destabilization of Atherosclerotic Plaques through Induction of Matrix Metalloproteinase-9 and IL-8
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Kim WJ, Lee WH
- KMID: 1637951
- Immune Netw.
- 2004 Jun;4(2):116-122.
- doi: 10.4110/in.2004.4.2.116
BACKGROUND: LIGHT (TNFSF14) is a member of tumor necrosis factor superfamily and is the ligand for TR2 (TNFRSF14/HVEM). LIGHT is known to have pro- inflammatory roles in atherosclerosis. METHODS: To... -
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- The Translocation of Nuclaer Factor Kappa B on Corneal Epithelial Cells after Ultraviolet B Irrradiation
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Lee DH, Choi KD, Joo CK
- KMID: 2125407
- J Korean Ophthalmol Soc.
- 2002 Jan;43(1):171-177.
PURPOSE: To seek the role of nuclear factor kappa B (NF-kB) on the corneal epithelial cell death after ultraviolet (UV) irradiation. METHODS: Human corneal epithelial cells transfected by Simian Virus 40... -
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- The Role of Nuclear Factor kB and Phosphatidylinositol 3 - kinase in Trypsinogen Activation in Cerulein - Stimulated Rat Pancreatic Acini
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Kim YJ, Kim YT, Hwang JH, Kim J, Jeong JB, Yoon YB, Kim CY
- KMID: 2085005
- Korean J Gastroenterol.
- 2001 Dec;38(6):427-432.
BACKGROUND/AIMS: Intra-acinar cell activation of trypsinogen is a critical event in cerulein-induced pancreatitis. However, little is known about the intracellular signal transduction systems involved in trypsinogen activation. This study focused... -
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- Inactivation of p73 Protein by Cervical Cancer-inducing HPV E6 Protein Novel p53-independent function of E6
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Namkoong S, Kim SJ, Kim EJ, Um SJ, Park JS
- KMID: 2026746
- Korean J Obstet Gynecol.
- 1998 Nov;41(11):2827-2834.
OBJECTIVE: Human papillomavirus (HPV) is strongly implicated as a causative agent in the etiology of cervical cancer. Of its gene products, E6 and E7 oncoproteins play major roles by inactivation... -
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- Identification of regulatory sequence within the promoter of M.leprae-specific 18-kDa gene and its binding factor(s)
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Kim MJ, Kim YK, Chae GT
- KMID: 2139281
- Korean Lepr Bull.
- 2000 Jun;33(1):107-113.
A central question to the pathogenesis of leprosy is how Mycobacterium leprae, the causative agent of leprosy, survives and replicates within macrophages. 18-kDa protein of M. leprae, a major antigen,... -
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- Nuclear Translocation of NF-kappaB/Rel Component by PCSC22 Isolated from Poria cocos Sclerotium
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Lee KY, Kim HY, Jeon YJ, Chang IY
- KMID: 2224510
- Korean J Anat.
- 2004 Jun;37(3):301-308.
The sclerotium of Poria cocos Wolf, which grows on the roots of pine trees, has long been used as a sedative and diuretic (Chang and But, 1987). The accumulating data... -
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- The Role of Nuclear Factor Kappa B on Lens Epithelial Cells after Ultraviolet B Irradiation
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Lee DH, Kim JK, Oh SH, Kim EK, Joo CK
- KMID: 1902563
- J Korean Ophthalmol Soc.
- 2004 Mar;45(3):500-506.
PURPOSE: This study was performed to determine the role of nuclear factor kappa B (NF-kappa B) on the lens epithelial cell death after ultraviolet (UV) irradiation. METHODS: Simian virus 40... -
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- Signaling Pathway of the Bacterial Lipopolysaccharide-induced Generation of Nitric Oxide in Rat Primary Astorcytes
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Kwang S, Park RK, Lee SY, Park MC
- KMID: 2340348
- J Korean Neuropsychiatr Assoc.
- 1999 Jul;38(4):881-893.
OBJECTIVES: Nitric oxide(NO)plays an important role in pathophysiology of stroke and various neurodegenerative diseases. This study is designed to elucidate the mechanisms by which signaling pathway of LPS-stimulated NO... -
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