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Ebola outbreak in Western Africa 2014: what is going on with Ebola virus?

Na W, Park N, Yeom M, Song D

The 2014 outbreak of Ebola virus disease (EVD) in West Africa, caused by Ebola virus (Zaire Ebola virus species), is the largest outbreak of EVD in history. It cause hemorrhagic...
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Data Fitting and Scenario Analysis of Vaccination in the 2014 Ebola Outbreak in Liberia

Xie Z

OBJECTIVES: This study aimed to extend an epidemiological model (SEIHFR) to analyze epidemic trends, and evaluate intervention efficacy. METHODS: SEIHFR was modified to examine disease transmission dynamics after vaccination for the...
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Purification and characterization of monoclonal IgG antibodies recognizing Ebola virus glycoprotein

Han BS, Jang HY, Racine T, Qiu X, Sin JI

PURPOSE: The goal of this study was to purify and characterize Ebola virus glycoprotein (GP)-specific IgG antibodies from hybridoma clones. MATERIALS AND METHODS: For hybridoma production, mice were injected by intramuscular-electroporation...
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Insights of window-bsed mechanism approach to visualize composite bioData point in feature spaces

Daoud M

In this paper, we propose a window-based mechanism visualization approach as an alternative way to measure the seriousness of the difference among data-insights extracted from a composite biodata point. The...
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What do we really fear? The epidemiological characteristics of Ebola and our preparedness

Ki M

Ebola virus disease (hereafter Ebola) has a high fatality rate; currently lacks a treatment or vaccine with proven safety and efficacy, and thus many people fear this infection. As of...
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Knowledge, attitudes, and behavioural risk factors regarding zoonotic infections among bushmeat hunters and traders in Nsukka, southeast Nigeria

Ozioko KU, Ikem Okoye C, Nduka Obiezue R, Awudu Agbu R

OBJECTIVES: In light of the dramatic spread of Ebola virus in some parts of Africa and the 2014 outbreak in Nigeria, a study was conducted to evaluate bushmeat dealers' knowledge...
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Progress of vaccine and drug development for Ebola preparedness

Choi WY, Hong KJ, Hong JE, Lee WJ

Since the first case of Ebola virus disease (EVD) in Guinea was reported in March 2014 by World Health Organization (WHO), the outbreak has continued through the year and the...
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Preferential production of IgM-secreting hybridomas by immunization with DNA vaccines coding for Ebola virus glycoprotein: use of protein boosting for IgG-secreting hybridoma production

Lee SH, Han BS, Choe J, Sin JI

PURPOSE: The goal of this study was to investigate the utility of DNA vaccines encoding Ebola virus glycoprotein (GP) as a vaccine type for the production of GP-specific hybridomas and...
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The 2013-2015 Ebola outbreak in West Africa

Kang JH, Chang WY, Choi S, Rho J, Lee KH

Zaire Ebola virus (EBOV) is a fatal human pathogen, with a high case fatality rate (CFR) averaging up to 78%. In March 2014, the World Health Organization (WHO) was made...
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