- Is It Possible to Predict Chemotherapy Response by the Gene Expression?
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Choi JH
- KMID: 1767512
- Korean J Gastroenterol.
- 2005 Jul;46(1):66-68.
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- In Vitro Adenosine Triphosphate-Based Chemotherapy Response Assay as a Predictor of Clinical Response to Fluorouracil-Based Adjuvant Chemotherapy in Stage II Colorectal Cancer
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Kwon HY, Kim IK, Kang J, Sohn SK, Lee KY
- KMID: 2344070
- Cancer Res Treat.
- 2016 Jul;48(3):970-977.
- doi: 10.4143/crt.2015.140
PURPOSE: We evaluated the usefulness of the in vitro adenosine triphosphate-based chemotherapy response assay (ATP-CRA) for prediction of clinical response to fluorouracil-based adjuvant chemotherapy in stage II colorectal cancer. MATERIALS AND... -
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- Clinical value of an adenosine triphosphate-based chemotherapy response assay in resectable stage III colorectal cancer
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Kim CD, Kim SH, Jung SH, Kim JH
- KMID: 2455983
- Ann Surg Treat Res.
- 2019 Aug;97(2):93-102.
- doi: 10.4174/astr.2019.97.2.93
PURPOSE: ATP-based chemotherapy response assay (ATP-CRA) is a well-documented and validated technology that can individualize chemotherapy. This study was undertaken to assess the usefulness of ATP-CRA in advanced colorectal cancer... -
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- Association between Chemotherapy-Response Assays and Subsets of Tumor-Infiltrating Lymphocytes in Gastric Cancer: A Pilot Study
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Lee JY, Son T, Cheong JH, Hyung WJ, Noh SH, Kim CB, Park CG, Kim HI
- KMID: 2391556
- J Gastric Cancer.
- 2015 Dec;15(4):223-230.
- doi: 10.5230/jgc.2015.15.4.223
PURPOSE: The purpose of this pilot study was to evaluate the association between adenosine triphosphate-based chemotherapy response assays (ATP-CRAs) and subsets of tumor infiltrating lymphocytes (TILs) in gastric cancer. MATERIALS AND... -
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- Chlorophyll derivatives (CpD) extracted from silk worm excreta are specifically cytotoxic to tumor cells in vitro
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Lee WY, Park JH, Kim BS, Han MJ, Hahn BS
- KMID: 1107340
- Yonsei Med J.
- 1990 Sep;31(3):225-233.
- doi: 10.3349/ymj.1990.31.3.225
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- Individualized Tumor Response Testing for Prediction of Response to Paclitaxel and Cisplatin Chemotherapy in Patients with Advanced Gastric Cancer
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Kim JH, Lee KW, Kim YH, Lee KH, Oh DY, Kim J, Yang SH, Im SA, Choi SH, Bang YJ
- KMID: 1713950
- J Korean Med Sci.
- 2010 May;25(5):684-690.
- doi: 10.3346/jkms.2010.25.5.684
The purpose of our study was to determine the most accurate analytic method to define in vitro chemosensitivity, using clinical response as reference standard in prospective clinical trial, and to... -
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- Modification of adriamycin-induced cytotoxicity by recombinant human interferon-gamma and/or verapamil in human stomach cancer cells
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Hong WS, Kim CM, Lee CT, Lee JO, Kang TW
- KMID: 1421919
- J Korean Med Sci.
- 1992 Sep;7(3):236-240.
- doi: 10.3346/jkms.1992.7.3.236
Recombinant human-interferon-gamma (rH-IFN-gamma) and verapamil (VRP), either alone or in combination, were evaluated in MTT assay for their modification effects on adriamycin-induced cytotoxicity against MKN-45, human stomach adenocarcinoma cells.... -
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- Efficacy of in vitro treatment of chronic myelogenous leukemia cell line, K562 cells, using 4-hydroperoxycyclophosphamide, alpha-interferon and gamma-interferon
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Lee JT, Park S, Lee JH, Kim BK, Kim NK
- KMID: 932127
- J Korean Med Sci.
- 1996 Feb;11(1):26-32.
- doi: 10.3346/jkms.1996.11.1.26
Alpha-interferon (alpha-IFN) and gamma-interferon (gamma-IFN) are highly effective biologic agents in the treatment of chronic myelogenous leukemia (CML). 4-hydroperoxycyclophosphamide (4-HC) is the most commonly used chemotherapeutic drug when purging bone... -
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- Heterogeneity of Adenosine Triphosphate-Based Chemotherapy Response Assay in Colorectal Cancer - Secondary Publication
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Huh JW, Park YA, Lee KY, Sohn SK
- KMID: 1103825
- Yonsei Med J.
- 2009 Oct;50(5):697-703.
- doi: 10.3349/ymj.2009.50.5.697
PURPOSE: Adenosine triphosphate-based chemotherapy response assay (ATP-CRA) is a well-documented and validated technology that can individualize chemotherapy for patients with lung, stomach, or breast cancer. This study explored the feasibility... -
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- ATP-Based Chemotherapy Response Assay in Primary or Recurrent Ovarian and Peritoneal Cancer
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Lee M, Kim SW, Nam EJ, Cho H, Kim JH, Kim YT, Kim S
- KMID: 2070217
- Yonsei Med J.
- 2014 Nov;55(6):1664-1671.
- doi: 10.3349/ymj.2014.55.6.1664
PURPOSE: To investigate chemosensitivity with an adenosine triphosphate-based chemotherapy response assay in patients with epithelial ovarian or peritoneal cancer according to tumor histology, grade, and disease status. MATERIALS AND METHODS: One... -
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- Growth Inhibition After Exposure to Transforming Growth Factor-beta1 in Human Bladder Cancer Cell Lines
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Lee C, Lee SH, Kim DS, Jeon YS, Lee NK, Lee SE
- KMID: 1794579
- Korean J Urol.
- 2014 Jul;55(7):487-492.
- doi: 10.4111/kju.2014.55.7.487
PURPOSE: Transforming growth factor-beta1 (TGF-beta1) plays a dual role in apoptosis and in proapoptotic responses in the support of survival in a variety of cells. The aim of this study... -
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- Impact of Grade, Hormone Receptor, and HER-2 Status in Women with Breast Cancer on Response to Specific Chemotherapeutic Agents by in vitro Adenosine Triphosphate-based Chemotherapy Response Assay
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Koo JS, Jung W, Shin E, Lee HD, Jeong J, Kim KH, Jeong H, Hong SW
- KMID: 1783147
- J Korean Med Sci.
- 2009 Dec;24(6):1150-1157.
- doi: 10.3346/jkms.2009.24.6.1150
This study was designed to assess whether histological and biological factors of breast cancer can predict chemoresponse to specific agents. Adenosine triphosphate-based chemotherapy response assay (ATP-CRA) was employed to retrieve... -
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- Combined treatment with silibinin and either sorafenib or gefitinib enhances their growth-inhibiting effects in hepatocellular carcinoma cells
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Gu HR, Park SC, Choi SJ, Lee JC, Kim YC, Han CJ, Kim J, Yang KY, Kim YJ, Noh GY, No SH, Jeong JH
- KMID: 2155291
- Clin Mol Hepatol.
- 2015 Mar;21(1):49-59.
- doi: 10.3350/cmh.2015.21.1.49
BACKGROUND/AIMS: Silibinin, the main component of silymarin, is used as a hepatoprotectant and exhibits anticancer effects against various cancer cells. This study evaluated the effects of a combination of silibinin... -
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- Clinical Significance of Thymidylate Synthase and Methylenetetrahydrofolate Reductase Gene Polymorphism in Korean Patients with Gastric Cancer
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Lee J, Jeong CK, Hong SP, Chong SY, Oh D, Hwang SG, Ahn DH, Kim S, Han JH, Kim NK
- KMID: 1767507
- Korean J Gastroenterol.
- 2005 Jul;46(1):32-38.
BACKGROUND/AIMS: Thymidylate synthase (TS) is a target enzyme of 5-fluorouracil (5-FU) and has a polymorphic 28 bp tandem repeated sequence. TS enhancer region (TSER) polymorphism has been associated with the... -
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