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Expression of Cell Cycle Regulatory and Apoptosis-related Proteins in Etoposide-treated Human Skin Fibroblast

Cho JW, Suh MH

  • KMID: 2007130
  • J Korean Cancer Assoc.
  • 2001 Feb;33(1):77-83.
PURPOSE: This study was designed to investigate effect of the etoposide on expression of cell cycle regulatory proteins and apoptosis-related proteins in human skin fibroblast (HSF). MATERIALS AND METHODS: HSF cells...
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New Insights into the Mechanism of the Down-Regulation of Mast Cells in the Treatment of Interstitial Cystitis: Possible Role of Siglecs

Lee T

  • KMID: 2232794
  • Int Neurourol J.
  • 2011 Jun;15(2):59-60.
No abstract available.
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Molecular mechanisms of luteinization

Sugino N

  • KMID: 2313991
  • Obstet Gynecol Sci.
  • 2014 Mar;57(2):93-101.
Dynamic changes in steroidogenesis occur in ovarian granulosa cells during ovulation after the LH surge. The ovulatory LH surge induces rapid up-regulation of steroidogenic acute regulatory (StAR) protein and rapid...
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Down regulation induced by intermitent intranasal spraying of gonadotropin releasing hormone(GnRH) in idiopathic male infertility

Kim YC, Choi HK, Cha KY

  • KMID: 1960407
  • J Korean Androl Soc.
  • 1991 Jun;9(1):37-40.
Gonadotropin Releasing Hormone(GnRH) appears to represent a more physiologic approach to increasing the release of the pituitary gonadotropin endogenously. This therapeutic agent is still being investigated. Among various modes of...
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The upstream sequence of Mycobacterium leprae 18-kDa gene confers transcription repression activity in orientation-independent manner

Kim HB, You JC

  • KMID: 1103317
  • Exp Mol Med.
  • 2004 Dec;36(6):510-514.
In order to understand the role of the upstream region of the Mycobacterium leprae 18-kDa gene on the gene regulation, the region was divided into two at the -50 position...
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Could Down-Regulation of Muscle-Specific MircoRNAs Provoke Functional Dyspepsia in Helicobacter pylori-Infected Stomach? (Gastroenterology 2011;140:189-198)

Lee BH, Kim N

  • KMID: 2326219
  • J Neurogastroenterol Motil.
  • 2011 Apr;17(2):200-201.
No abstract available.
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Investigation of Oxidative Stress and Development of Lower Urinary Tract Symptoms in the Urinary Bladder following Partial Bladder Outlet Obstruction by Proteomic Approach

Shim JH, Kim HJ

  • KMID: 2293813
  • Korean J Urol.
  • 2005 Dec;46(12):1337-1343.
PURPOSE: This study investigated the pathophysiological mechanism using the proteomic approach to detect the marker proteins for the development of lower urinary tract symptoms following a partial bladder outlet obstruction...
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Prognostic Significance of KAI-1 and Survivin Expressions in Ovarian Epithelial Carcinomas

Lee JH, Lee SM, Choi JS

  • KMID: 1972900
  • Cancer Res Treat.
  • 2003 Aug;35(4):323-329.
PURPOSE: The purpose of this study was to evaluate the expressions of KAI-1 and survivin, and to investigate their correlation with the clinical stage and survival rate of patients with...
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Clinical Efficacy of Long-term Down Regulation (LTDR) for Intrauterine Insemination or In Vitro Fertilization in Patients with Endometriosis or Adenomyosis

Yang KM, Yoo KJ, Choi BC, Kim KH, Lee HB, Lee JH, Song IO, Hong JH, Koong MK, Jun JY, Kang IS

  • KMID: 1569624
  • Korean J Obstet Gynecol.
  • 2000 Oct;43(10):1775-1779.
No abstract available.
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Coordinate Regulation of Neurite Outgrowth by LRRK2 and Its Interactor, Rab5

Heo HY, Kim KS, Seol W

Neurite outgrowth and its maintenance are essential aspects of neuronal cells for their connectivity and communication with other neurons. Recent studies showed that over-expression of either leucine-rich repeat kinase 2...
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Intracerebroventricular Kainic Acid-Induced Damage Affects Blood Glucose Level in d-glucose-fed Mouse Model

Kim CH, Hong JS

We have previously reported that the intracerebroventricular (i.c.v.) administration of kainic acid (KA) results in significant neuronal damage on the hippocampal CA3 region. In this study, we examined possible changes...
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Immunohistochemical Expression of p53, E-cadherin, and nm23 Proteins in Metastatic Carcinoma of Neck Lymph Node and Corresponding Primary Carcinoma

Kim JK, Kwon OJ, Kim BH

  • KMID: 1725721
  • Korean J Pathol.
  • 2000 Sep;34(9):615-624.
This study was carried out to evaluate the immunohistochemical expressions of p53, E-cadherin, and nm23 proteins in 114 cases of metastatic carcinoma of the neck lymph node (MTLNCA) and corresponding...
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Down-Regulation of Aquaporin 4 in the Lithium-Treated Rat Brain

Kim S, Jung YW

  • KMID: 2128894
  • Korean J Anat.
  • 2007 Dec;40(4):311-317.
Lithium has long been a primary drug used to treat bipolar mood disorder. Recently, in vivo and in vitro studies have demonstrated neuroprotective actions of lithium, even though therapeutic mechanisms...
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Prognostic Implication of 15-Hydroxyprostaglandin Dehydrogenase Down-Regulation in Patients with Colorectal Cancer

Kang PS, Kim JH, Moon OI, Lim SC, Kim KJ

PURPOSE: Prostaglandin (PG) E2 is known to be closely related to cancer progression and is inactivated by 15-hydroxyprostaglandin dehydrogenase (PGDH). 15-PGDH is shown to have tumor suppressor activity and to...
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Gene Expression in Cultured Keloid Fibroblasts

Kim DH, Kim UK, Choi KH, Park K

  • KMID: 2440723
  • Korean J Dermatol.
  • 2019 Feb;57(2):59-65.
BACKGROUND: Keloids are the result of an overgrowth of dense fibrous tissue. The mechanisms involved in keloid formation remain unknown. OBJECTIVE: To understand the mechanism of keloid formation, differences in gene...
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Regulation of Estrogen Receptor mRNA in Rat Anterior Pituitary Gland

Chun MS, Park DB, Park YB, Kam KY, Kim CM, Yoo KJ

  • KMID: 2331078
  • J Korean Soc Endocrinol.
  • 1997 Dec;12(4):518-527.
The estrogen receptor (ER) is present in a wide variety of mammalian tissues and is required for the physiological responses of estrogen, including estrogen-induced tissue-specific changes in gene expression. But...
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Active adenosine transporter-mediated adenosine entrance into HL-60 cells leads to the induction of apoptosis through down-regulation of c-Myc

Hong SH, Jeong SY, Ahn SG, Hwang IS, Kim IK

  • KMID: 2052796
  • Exp Mol Med.
  • 1997 Sep;29(3):183-190.
Although adenosine (Ado) is being recently recognized as a potent inducer of apoptosis, molecular mechanism of apoptosis by Ado remains to be elucidated. In this study we observed that c-Myc...
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MicroRNA profiling of tacrolimus-stimulated Jurkat human T lympocytes

Lee HK, Chung SY, Na Choi SJ

PURPOSE: This study investigated the Jurkat T cell line expresses cytotoxicity when treated with different concentrations of FK506, and analyzed the expression pattern of microRNA when stimulated by FK506 using...
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Altered Regulation of 11beta-hydroxysteroid Dehydrogenase II in the Kidney of Rats with Experimental Hypertension

Kang SS, Kim SW, Lee JU

The present study was aimed at investigating the role of type II 11beta-hydroxysteroid dehydrogenase (IIbeta- HSD II) in the development of hypertension. Two-kidney, one-clip (2K1C), deoxycorticosterone acetate (DOCA)/salt, or NG-nitro-L-arginine...
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The Modulatory Role of Spinally Located Histamine Receptors in the Regulation of the Blood Glucose Level in D-Glucose-Fed Mice

Sim YB, Park SH, Kim SS, Kim CH, Kim SJ, Lim SM, Jung JS, Ryu OH, Choi MG, Suh HW

The possible roles of spinal histamine receptors in the regulation of the blood glucose level were studied in ICR mice. Mice were intrathecally (i.t.) treated with histamine 1 (H1) receptor...
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