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A study on the liver dysfunction due to dimethylformamide

Kang SK, Jang JY, Rhee KY, Chung HK

  • KMID: 1694387
  • Korean J Occup Environ Med.
  • 1991 Feb;3(1):58-64.
No abstract available.
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Increased Growth of Human Leukemic HL-60 Cells by Dimethyl Sulfoxide and Dimethylformamide

Kang IC, Oh HM

  • KMID: 1550777
  • Korean J Immunol.
  • 1999 Sep;21(3):285-289.
A recent study has proposed that dimethyl sulfoxide (DMSO) increases the number of HL-60 cells in high cell density conditions by inhibiting cell density-dependent apoptosis. We observed that dimethylformamide (DMF),...
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A Case of Fulminant Hepatitis Due to Dimethylformamide

Heo JH, lee KL, Han SG, Kim HJ, Pai YM, Whang YH, Kang PJ, Kim CH, Cho SL

  • KMID: 1548554
  • Korean J Gastroenterol.
  • 1999 Oct;34(4):547-550.
Dimethylformamide (DMF) is widely used as an organic solvent in chemical industry. The effects of DMF exposure in human are not well documented. Complaints of abdominal pain, nausea, vomiting, headache,...
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A Case of Toxic Hepatitis after the Exposure of Dimethylformamide

Joo MD, Sohn YD, Choi WI

  • KMID: 2331480
  • J Korean Soc Emerg Med.
  • 2006 Oct;17(5):515-518.
Dimethylformamide (DMF) is a major solvent predominately used in synthetic leather and electrical equipment production. The effects of DMF exposure in humans are not well known or documented in the...
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Clinical Outcomes of Occupational Exposure to N,N-Dimethylformamide: Perspectives from Experimental Toxicology

Kim TH, Kim SG

  • KMID: 2317006
  • Saf Health Work.
  • 2011 Jun;2(2):97-104.
N,N-Dimethylformamide (DMF) is globally used as an organic solvent in the production of synthetic leather and resins because of its low volatility, making it an attractive industrial material. Despite its...
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A Suspicious Case of Dimethylformamide Induced Fulminant Hepatitis in Synthetic Leather Workers

Kim SK, Lee SJ, Chung KC

  • KMID: 2141619
  • Korean J Occup Environ Med.
  • 1995 Feb;7(1):186-190.
A man who worked in the synthetic leather manufacturing plant for 3 months died at November 3. Author review the medical record, the death certificate, and interviewed his wife and...
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A Case of Acute Toxic Hepatitis induced by brief exposure to Dimethylformamide

Roh JR, Sohn JG, Kim JH, Park SJ

  • KMID: 1607578
  • Korean J Occup Environ Med.
  • 2005 Jun;17(2):144-148.
Dimethylformamide (DMF), a widely used industrial solvent, has been reported to induce subtle to clinically overt hepatotoxicity. Liver injury due to occupational exposure through inhalation and skin contact has been...
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A Study on the N-methylformamide Excretion Rate of Workers at Synthetic Leather Factories in Korea

Kim KW, Choi BS, Kang SK, Moon YH

  • KMID: 2028060
  • Korean J Occup Environ Med.
  • 1999 Mar;11(1):106-112.
This study was conducted to examine the excretion rate of dimethylformamide (DMF) from the workers exposed to DMF. The study was done at two synthetic leather factories located in Kyeonggi-do...
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Hepatotoxicity in Rats Treated with Dimethylformamide or Toluene or Both

Kim KW, Chung YH

  • KMID: 2317834
  • Toxicol Res.
  • 2013 Sep;29(3):187-193.
The effects of toluene in dimethylformamide (DMF)-induced hepatotoxicity were investigated with respect to the induction of cytochrome P-450 (CYP) and the activities of related enzymes. The rats were treated intraperitoneally...
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Seasonal Variations of the Urinary N-Methylformamide Concentration among Workers at a Synthetic Leather Factory

Lee KY, Byeon JH, Song HR, Kim JH, Ko KW, Lee YH

  • KMID: 2074999
  • Korean J Occup Environ Med.
  • 2003 Jun;15(2):162-172.
OBJECTIVES: This study was carried out to identify seasonal variations of urinary concentrations of N-methylformamide (NMF) among workers employed at a synthetic leather factory. METHODS: Study subjects consisted of 16...
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Influencing Facotrs that Affect the Biological Monitoring of Workers Exposed to N,N-Dimethylformamide in Textile Coating Factories

Chung IS, Kim JG, Choi SK, Bae JY, Lee MY

  • KMID: 792405
  • J Prev Med Public Health.
  • 2006 Mar;39(2):171-176.
OBJECTIVES: The objective of this study is to assess the factors influencing biological monitoring of textile coating factory workers exposed to N,N-dimethylformamide(DMF). METHODS: We studied 35 workers who were...
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The Metabolism and Liver Toxicity of N,N-dimethylformamide in the Isolated Perfused Rat Liver

Koh SB, Cha BS, Park JK, Chang SH, Chang SJ

N,N-dimethylformamide (DMF) is metabolized by the microsomal cytochrome p-450 into mainly N-hydroxymethyl- N-methylformamide (HMMF), which further breaks down to N-methyformamide (NMF). However, the detailed mechanism of its toxicity remains unclear....
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Investigation of Chemotactic Activities in Differentiated HL-60 Cells by a Time-lapse Videomicroscopic Assay

Jung YJ, Woo SY, Ryu KH, Jang MH, Miyasaka M, Seoh JY

BACKGROUND: Chemotaxis is one of the cardinal functions of leukocytes, which enables them to be recruited efficiently to the right place at the right time. Analyzing chemotactic activities is important...
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Radiosynthesis of [11C]6-OH-BTA-1 in Different Media and Confirmation of Reaction By-products

Lee HJ, Jeong JM, Lee YS, Kim HW, Lee EK, Lee DS, Chung JK, Lee MC

  • KMID: 1518947
  • Nucl Med Mol Imaging.
  • 2007 Jun;41(3):241-246.
PURPOSE: [11C]6-OH-BTA-1 ([N-methyl-11C]2-(4'-methylaminophenyl)-6-hydroxybenzothiazole, 1), a -amyloid imaging agent for the diagnosis of Alzheimer's disease in PET, can be labeled with higher yield by a simple loop method. During the synthesis...
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Phenotypic and Functional Analysis of HL-60 Cells Used in Opsonophagocytic-Killing Assay for Streptococcus pneumoniae

Kim KH, Seoh JY, Cho SJ

Differentiated HL-60 is an effector cell widely used for the opsonophagocytic-killing assay (OPKA) to measure efficacy of pneumococcal vaccines. We investigated the correlation between phenotypic expression of immunoreceptors and phagocytic...
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Induction of Hepatic Microsomal Cytochrome P450 by N,N-dimethylformamide in Sprague-Dawley Rats

Koh SB, Cha BS, Kim KJ, Kang SK, Joung HS

  • KMID: 2282984
  • Korean J Prev Med.
  • 1999 Feb;32(1):88-94.
OBJECTIVES: In order to gain a better understanding of the mechanism of DMF toxicity, recent studies have focused on hepatic drug metabolizing enzymes. In this study, we investigated the effects...
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Compensation for Work-Related Hematologic, Liver, and Infectious Diseases

Kim JW, Kang DM

Occupational diseases may be defined only medically or scientifically, and even then, their definition is not simple. However, compensable occupational diseases involve the additional layer of legal systems and social...
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Surveillance of Work-related Diseases in Kumi

Kim SA, Kim JS, Jeon HR, Jung SJ, Kim SW, Lee CY, Ham JO, Yoo JY, Choi TS, Goo HB, Cho MH, Woo KH

  • KMID: 2028213
  • Korean J Occup Environ Med.
  • 2003 Mar;15(1):95-110.
OBJECTIVES: Area-based occupational disease surveillance in Kumi (KODS) was used to collect data on occupational diseases. The data was used to estimate the magnitude of the diseases, to analyze for...
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