Korean J Occup Environ Med.  1999 Mar;11(1):106-112.

A Study on the N-methylformamide Excretion Rate of Workers at Synthetic Leather Factories in Korea

• Kim KW
• Choi BS
• Kang SK
• Moon YH

Abstract

This study was conducted to examine the excretion rate of dimethylformamide (DMF) from the workers exposed to DMF. The study was done at two synthetic leather factories located in Kyeonggi-do from the period of May 2 to 30, 1996. N-methyl- formamide (NMF) concentrations in urine were measured and compared by the three exposure level of DMF in air. The mean concentration of the Low (dry and winder part). Moderate (rinsing part) and High (mixing and coating part) exposure group were 3.99+/-3.54. 10.19 +/-5.69 and 32.10+/-7.87 mg/m3 during workshift of 8 hours, respectively. The mean concentration of urinary N-methylforinamide (NMF) were 2.13+/-2.58, 11.16+/-4.98 and 26.24 +/-7.35 mg/g creatinine, respectively. The concentration of NMIF in urine could reach to maximum in 3 hours and was reduced nearly to zero in about 18 hours after exposure to DMF.

Keyword

Biological monitoring; Human worker study; Dimethylforinainide(DMF); Nmethylformamide(NMF)

MeSH Terms

Creatinine
Dimethylformamide
Environmental Monitoring
Gyeonggi-do
Korea*
Creatinine
Dimethylformamide