- Expression of c-myc oncogene in 1-2 DMH induced colon cancer of Wistar rats
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Cho KK, Bae OS, Kang JS
- KMID: 1694130
- J Korean Cancer Assoc.
- 1991 Sep;23(3):518-523.
No abstract available. -
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- The Effects of Dimenhydrinate on Eye Tracking Tests and VOR
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Chung YS, Chung WK
- KMID: 1559728
- Korean J Otolaryngol-Head Neck Surg.
- 1998 Jul;41(7):851-855.
BACKGROUND AND OBJECTIVES: Dimenhydrinate is known to act on the vestibular system, causing vestiular suppression. But the effects related with therapeutic dosage on eye tracking tests and vestibulo-ocular reflex (VOR)... -
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- Effect of Antivertigo Medications on Vestibular Function in Healthy Human Subjects
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Chung JY, Lee SH, Hwang SH
- KMID: 1524935
- Korean J Aerosp Environ Med.
- 2007 Dec;17(3):108-112.
BACKGROUND: Motion sickness is one of the major problems of aerospace medical concern. Vestibule plays an important role in giving rise to motion sickness. Drugs preventing motion sickness have a... -
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- The Morphologic Study of Vitamin A(Retinol) on 1, 2-Dimethylhydrazine Induced Colon Carcinogenesis in the Rats
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Hong KS
- KMID: 1965796
- Ewha Med J.
- 1989 Dec;12(4):241-251.
- doi: 10.12771/emj.1989.12.4.241
Induction of intestinal tumor by subcutaneous injection of 1, 2-dimethylhydrazine(DMH), 20 mg/kg/week, during 20 weeks was studied in rats fed by vitamin A(retinol) 50 microg, 500 microg/day. Mucosal epithelial cell hyperplasia... -
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- Candida albicans test for the screening of phototoxicity in anthistamines
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Kim TH
- KMID: 2038867
- Korean J Dermatol.
- 1993 Apr;31(2):191-196.
BACKGROUND: Antihistamine drugs are used widely in many conditions. Although some antihistamines may cause a photosensitive reaction,many physicians are not awae of it. OBJECTIVE: For examination of the phototoxic potential of... -
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- The Light and Electron Microscopic Study of Mucosal Changes of Colonic Lesion Induced by 1,2-Demethylhydrazined 2HCl in the Rats
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Hong KS, Han WS, Kim OK
- KMID: 1965709
- Ewha Med J.
- 1987 Mar;10(1):5-19.
- doi: 10.12771/emj.1987.10.1.5
The fact that the administration of 1,2-dimethylhydrazine 2Hcl(DMH) to rats by weekly subcutaneous injections causes the development of epithelial tumors of the large intestine has been known. But the axact... -
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- Role of Protein Kinase C in Abnormal Proliferation of Vascular Endothelial Cell induced by 1,2-Dimethylhydrazine; Analysis of Isoform
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Lee J, Bae YC, Park SY, Moon JS, Nam SB
- KMID: 2203288
- J Korean Soc Plast Reconstr Surg.
- 2007 Jan;34(1):8-12.
PURPOSE: Protein tyrosine kinase(PTK), protein kinase C(PKC), oxidase, as a mediator, have been known to take a role in signal transduction pathway of angiogenesis. The authors confirmed that PKC is... -
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- Activity of Protein Kinase C in Abnormally Proliferated Vascular Endothelial Cells
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Bae YC, Park SY, Nam SB, Moon JS, Choi SJ
- KMID: 2203289
- J Korean Soc Plast Reconstr Surg.
- 2007 Jan;34(1):13-17.
PURPOSE: To understand the pathogenesis of the disease that presents abnormally proliferated vascular endothelial cells, a model of DMH(1,2-dimethylhydrazine)-induced abnormal proliferation of HUVECs(Human Umbilical Vein Endothelial Cells) was made. We... -
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- RT-PCR of Up-Regulated Factors in Abnormally Proliferated Vascular Endothelial Cells by 1,2- Dimethylhydrazine
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Kim SH, Kang YS, Bae YC, Park SY, Nam SB
- KMID: 1943206
- J Korean Soc Plast Reconstr Surg.
- 2005 Nov;32(6):689-698.
Many studies for verifying angiogenesis have been in progress, especially in the field of abnormal vascular proliferation to explain the pathogenesis and to develop a treatment of several diseases. In... -
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- Gene Expression Profiling of 1,2-Dimethylhydrazine-Stimulated Human Umbilical Vein Endothelial Cells
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Kim HO, Kang YS, Bae YC, Park SY, Hwang SM, Nam SB
- KMID: 2203530
- J Korean Soc Plast Reconstr Surg.
- 2004 Nov;31(6):858-864.
The purposes of this study are to establish standard model in which endothelial cell proliferations are induced by DMH stimulation in vitro, and to analyze the gene expressions of proliferative... -
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- A Study for the Mechanism of Abnormal Proliferation in Vascular Endothelial Cells using Inhibitors to the Signal Transduction Pathway
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Bae YC, Park SY, Nam SB, Herh JY, Kang YS
- KMID: 2120052
- J Korean Soc Plast Reconstr Surg.
- 2006 Jan;33(1):5-12.
Protein tyrosine kinase(PTK), protein kinase C(PKC), oxidase, as a mediator, take a significant role in signal transduction pathway of angiogenesis. The authors utilized the inhibitors, targeting the formation of three... -
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- Sequential Changes in Aberrant Crypt Foci and Lectin Expression in the Early and Late Stages of DMH-Induced Colon Carcinogenesis in Rats
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Won HS, Maeng LS, Chae HS, Kim HK, Cho YS, Kang JH, Jang HS, Ryu MR
- KMID: 2284269
- Gut Liver.
- 2012 Apr;6(2):229-234.
BACKGROUND/AIMS: The purpose of this study was to investigate the malignant potential of aberrant crypt foci (ACF) by measuring the multiplicity of crypts and lectin expression in the early and... -
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- Effect of Dietary CLA Isomers on Apoptosis and Cell Proliferation in Colonic Mucosa of DMH-Treated Rats
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Park HS, Kwon PS, Park JH, Ha YL
- KMID: 2269681
- Korean J Nutr.
- 2003 Sep;36(7):661-666.
The study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid (CLA) isomers on colon carcinogenesis in 1,2-dimethylhydrazine (DMH)-treated rats by determining the levels of apoptosis, cell proliferation,... -
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- Characterization of the Expression of PKCalpha(Isoform) in DMH-induced Vascular Endothelial Proliferation
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Nam SB, Bae YC, Park SY, Choi SJ
- KMID: 2322377
- J Korean Soc Plast Reconstr Surg.
- 2007 Nov;34(6):679-684.
PURPOSE: DMH(1,2-dimethylhydrazine) has been known to induce vascular neoplasm such as malignant endothelioma in animal experiment, through induction of abnormal proliferation of HUVECs. In our previous studies, 11 types of... -
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- Effect of Dietary Conjugated Linoleic Acid (CLA) Isomers on Tumor Incidence and the Protein Expression of Cyclooxygenase-2 and Protein Kinase C in Colonic Mucosa of DMH-Treated Rats
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Park HS, Chun CS, Yoon JH
- KMID: 2269800
- Korean J Nutr.
- 2004 Nov;37(9):763-770.
This study was designed to compare the anti-carcinogenic effect of conjugated linoleic acid isomers on tumor incidence, cell proliferation and the levels of thromboxane (TX)B2, prostaglandin (PG)E2 and 1,2-diacylglycerol (DAG),... -
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- Anti-Oxidative Effect of Myrtenal in Prevention and Treatment of Colon Cancer Induced by 1, 2-Dimethyl Hydrazine (DMH) in Experimental Animals
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Lokeshkumar B, Sathishkumar V, Nandakumar N, Rengarajan T, Madankumar A, Balasubramanian MP
- KMID: 2380297
- Biomol Ther.
- 2015 Sep;23(5):471-478.
- doi: 10.4062/biomolther.2015.039
Colon cancer is considered as the precarious forms of cancer in many developed countries, with few to no symptoms; the tumor is often diagnosed in the later stages of cancer.... -
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- Physicochemical Requirement for the Vegetative Growth of Schizophyllum commune Collected from Different Ecological Origins
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Imtiaj A, Jayasinghe C, Lee GW, Kim HY, Shim MJ, Rho HS, Lee HS, Hur H, Lee MW, Lee UY, Lee TS
- KMID: 2052885
- Mycobiology.
- 2008 Mar;36(1):34-39.
- doi: 10.4489/MYCO.2008.36.1.034
Schizophyllum commune is an edible and medicinal mushroom widely distributed in the world. The optimal growth conditions for the mycelia of 10 strains of the fungus were investigated. The temperature... -
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- Effect of Different Amount of Dietary n-3 PUFA on Colon Carcinogenesis in DMH-treated Rats
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Park HS, Kwak HK, Kim MS
- KMID: 2269915
- Korean J Nutr.
- 2005 Dec;38(10):807-816.
The objective of the study was to observe the effect of n-3 PUFA on cell proliferation and apoptosis by determining mRNA and protein of COX-2 and eicosanoid product and the... -
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