- Effect of Dexamethasone and Epinephrine on Metallothionein Level in the Perfused Rat Liver
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Lee HS, Oh SH
- KMID: 692893
- Yonsei Med J.
- 1980 Jun;21(1):18-23.
- doi: 10.3349/ymj.1980.21.1.18
The effect of dexamethasone (10(-5)M) and epinephrine (10(-6)M) on the biosynthesis of metallothionein (MT) in the perfused rat liver was investigated. MT synthesis was determined by measuring the incorporation of... -
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- Histochemical and Ultrastructural Studies of Hepatic Fibrogenesis; Its Initiation and the Effect of Dexamethasone in Rats
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Kim CJ, Park CI, Kim CS, Lee YB
- KMID: 692940
- Yonsei Med J.
- 1982 Dec;23(2):89-100.
- doi: 10.3349/ymj.1982.23.2.89
Intralobular fibrogenesis of the liver following hepatocellular damage has long been a controversial subject in regard to its initiation and prevention. To investigate the site of hepatic fibrogenesis and the... -
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- Regulation of leptin gene expression by insulin and growth hormone in mouse adipocytes
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Lee KN, Jeong IC, Lee SJ, Oh SH, Cho MY
- KMID: 1457535
- Exp Mol Med.
- 2001 Dec;33(4):234-239.
The role of leptin in the control of obesity, insulin resistance and type II diabetes has been reported, however, the regulatory mechanism of leptin in animals affected by hormones is... -
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- Dexamethasone enhances phospholipase D activity in M-1 cells
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Kim WJ, Lee MJ, Park MA, Jung JS, Uhlinger D, Kwak JY
- KMID: 755082
- Exp Mol Med.
- 2000 Sep;32(3):170-177.
Phospholipase D (PLD) is an enzyme involved in signal transduction and widely distributed in mammalian cells. The signal transduction pathways and role for phospholipid metabolism during hormonal response in... -
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- Fasting-induced Down-regulation of NADPH-diaphorase in the Magnocellular PVN of Rats
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Lee JY, Kang DW, Kim DG, Jahng JW
- KMID: 1103916
- Yonsei Med J.
- 2004 Oct;45(5):917-922.
- doi: 10.3349/ymj.2004.45.5.917
In this study, we examined if glucocorticoids are required for the fasting-induced decrease of neuronal nitric oxide synthase (nNOS) in the magnocellular division of the paraventricular nucleus (PVN). Rats were... -
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- Exposure to Toluene Diisocyanate (TDI) Induces IL-8 Production from Bronchial Epithelial Cells: Effect of Pro-inflammatory Cytokines
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Lee YM, Kim HA, Park HS, Lee SK, Nahm DH
- KMID: 1086736
- J Korean Med Sci.
- 2003 Dec;18(6):809-812.
- doi: 10.3346/jkms.2003.18.6.809
This investigation was designed to confirm IL-8 production from human bronchial epithelial cells with toluene diisocyanate (TDI) exposure and to examine the effects of pro-inflammatory cytokine and dexamethasone. We cultured... -
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- The Effect of Corticosteroid on the Fetal Pulmonary Maturation of Rats with Streptozotocin-Induced Diabetes
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Lee KG, Yoo MS, Choi IJ
- KMID: 693023
- Yonsei Med J.
- 1986 Jun;27(2):121-131.
- doi: 10.3349/ymj.1986.27.2.121
The effect of dexamethasone of the maturation of the fetal lungs of rats with streptozotocin-induced diabetes was studied morphologically and biochemically. By light and electron microscopy there was little difference... -
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- Anti-inflammatory effects of a Houttuynia cordata supercritical extract
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Shin S, Joo SS, Jeon JH, Park D, Jang MJ, Kim TO, Kim HK, Hwang BY, Kim KY, Kim YB
- KMID: 1093504
- J Vet Sci.
- 2010 Sep;11(3):273-275.
- doi: 10.4142/jvs.2010.11.3.273
Anti-inflammatory effects of Houttuynia cordata supercritical extract (HSE) were investigated in a carrageenan-air pouch model. HSE (200 mg/kg, oral) suppressed exudation and albumin leakage, as well as inflammatory cell infiltration.... -
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- Chemokines, osteopontin, ICAM-1 gene expression in cultured rat mesangial cells
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Lee SK, Park JY, Chung SJ, Yang WS, Kim SB, Park SK, Park JS
- KMID: 1064964
- J Korean Med Sci.
- 1998 Apr;13(2):165-170.
- doi: 10.3346/jkms.1998.13.2.165
To investigate whether MCP-1, CINC, RANTES, osteopontin and ICAM-1 mRNA could be induced in cultured rat mesangial cells by interleukin-1beta(IL-1beta), tumor necrosis factor-alpha (TNF-alpha) and lipopolysaccharide (LPS), and whether ... -
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- Repression of TNF-alpha-induced IL-8 expression by the glucocorticoid receptor-beta involves inhibition of histone H4 acetylation
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Kim SH, Kim DH, Lavender P, Seo JH, Kim YS, Park JS, Kwak SJ, Jee YK
- KMID: 1123803
- Exp Mol Med.
- 2009 May;41(5):297-306.
- doi: 10.3858/emm.2009.41.5.033
Increased expression of a number of proinflammatory genes, including IL-8, is associated with inflammatory conditions such as asthma. Glucocorticoid receptor (GR)beta, one of the GR isoforms, has been suggested to... -
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- Deflazacort Increases Osteoclast Formation in Mouse Bone Marrow Culture and the Ratio of RANKL/OPG mRNA Expression in Marrow Stromal Cells
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Chung H, Kang YS, Hwang CS, Moon IK, Yim CH, Choi KH, Han KO, Jang HC, Yoon HK, Han IK
- KMID: 648360
- J Korean Med Sci.
- 2001 Dec;16(6):769-773.
- doi: 10.3346/jkms.2001.16.6.769
Information on precise effects of deflazacort on bone cell function, especially osteoclasts, is quite limited. Therefore, the present study was undertaken to test effects of deflazacort on osteoclast-like cell formation... -
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- Identification of glucocorticoid response element of the rat TRH gene
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Lee GC, Yang IM, Kim BJ, Woo JT, Kim SW, Kim JW, Kim YS, Choi YK
- KMID: 1051555
- Korean J Intern Med.
- 1996 Jun;11(2):138-144.
OBJECTIVES: It was suggested that glucocorticoid exerts cell-specific effects on thyrotropin-releasing hormone (TRH) gene expression at the transcriptional level. Although there is no typical palindromic glucocorticoid response element (GRE) on... -
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