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Effect of Deoxycholic Acid on the Proliferation and Apoptosis of HCT116 Colon Cancer Cells

Park DG

  • KMID: 2004406
  • J Korean Surg Soc.
  • 2005 Mar;68(3):211-217.
PURPOSE: Bile acids were considered as a promoting factor for colon cancers. It has been suggested that bile acids could promote cellular proliferation or apoptosis according to their concentration. Therefore,...
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Prurigo Pigmentosa after Injection Lypolysis with Phosphatidylcholine and Deoxycholate

Yang JY, Kim SK

  • KMID: 2353449
  • Korean J Dermatol.
  • 2016 Sep;54(8):673-674.
No abstract available.
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Biliary Bile Acid Analysis in the Patients with Bile Duct Cancer

Lee JH, Park YH, Seo JH, Chung JB, Lee SJ, Chung JP, Song SY, Kang JK

  • KMID: 2304632
  • Korean J Gastroenterol.
  • 2000 Jan;35(1):103-110.
BACKGROUND/AIMS: Bile acids including deoxycholic acid (DCA) have been known as carcinogenic on human colonic mucosa. However, limited data on changes of bile acid composition in the patients with bile duct cancer are...
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Bile acid modulation of gastroinstinal smooth muscle contraction and ionic currents

Lee HK, Lee KH

  • KMID: 1917027
  • Korean J Physiol Pharmacol.
  • 2000 Aug;4(4):333-338.
We have examined whether bile acids can affect the electrical and mechanical activities of circular smooth muscle of canine colon and ileum, using isometric tension measurement or patch clamp technique. It was found...
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The Effect of Deoxycholic Acid on Secretion and Motility in the Rat and Guinea Pig Large Intestine

Kim NH, Park JH, Park JS, Joung YH

  • KMID: 2395430
  • J Neurogastroenterol Motil.
  • 2017 Oct;23(4):606-615.
  • doi: 10.5056/jnm16201
BACKGROUND/AIMS: Bile acid is an important luminal factor that affects gastrointestinal motility and secretion. We investigated the effect of bile acid on secretion in the proximal and distal rat colon...
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Effects of DCA on Cell Cycle Proteins in Colonocytes

Ha YH, Park DG

PURPOSE: Evidence that indicates bile acid is a promoter of colon cancer exists. Deoxycholic acid (DCA) modifies apoptosis or proliferation by affecting intracellular signaling and gene expression. However, because previous...
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The role of G protein in the activation of phospholipase C from bovine brain

Kim JH, Lee DJ, Byun YJ

The objective of the present study was to identify the characteristics of phospholipase C (PLC) isozymes purified from bovine brain and to investigate their interrelationship with G protein. The purified PLC...
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Decellularization of Trachea With Combined Techniques for Tissue-Engineered Trachea Transplantation

Batioglu-Karaaltin A, Ovali E, Karaaltin , Yener M, Yılmaz M, Eyüpoğlu F, Yılmaz YZ, Bozkurt ER, Demir N, Konuk E, Bozdağ ES, Yiğit O, Cansiz H

OBJECTIVES: The purpose of this study is to shorten the decellularization time of trachea by using combination of physical, chemical, and enzymatic techniques. METHODS: Approximately 3.5-cm-long tracheal segments from 42 New...
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The relationship of bacterial and Helicobacter infection to composition of bile acid in biliary tract diseases

Lee BS, Roe IH, Nam SW, Yoo K, Park HJ, Kim JW, Shin JH, Lee JH

  • KMID: 2253145
  • Korean J Med.
  • 2001 Mar;60(3):215-221.
BACKGROUND: Bacterial and Helicobacter gene were commonly detected in diseased human bile, although the meaning of the presence of Helicobacter in biliary tract is still unclear. The aim of this...
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Effects of Culture Condition on Secretion of Phospholipase from Candida albicans

Shin WS, Lee KH, Park JY, Koh CM

  • KMID: 1549920
  • Korean J Med Mycol.
  • 1997 Dec;2(2):123-128.
BACKGROUND: The dimorphic yeast, Candida albicans, is considered as a dangerous opportunistic pathogen in immunocompromised hosts. Several phospholipases of C. albicans are known to be secreted into the culture medium....
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Modulation of Colon Cancer Cell Invasiveness Induced by Deoxycholic Acid

Kim HS, Lee YK, Kim JW, Baik SK, Kwon SO, Jang HI

  • KMID: 782732
  • Korean J Gastroenterol.
  • 2006 Jul;48(1):9-18.
BACKGROUND/AIMS: Deoxycholic acid (DCA), a secondary bile acid, has been implicated to promote colon cancer growth and progression. However, its molecular mechanisms are largely unknown. In this study, we investigated...
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Deoxycholic Acid-Induced Signal Transduction in HT-29 Cells: Role of NF-kappa B and Interleukin-8

Lee DK, Park SY, Baik SK, Kwon SO, Chung JM, Oh ES, Kim HS

  • KMID: 772624
  • Korean J Gastroenterol.
  • 2004 Mar;43(3):176-185.
BACKGROUND/AIMS: Deoxycholic acid (DCA) has been appeared to be an endogenous colon tumor promoter. In this study, we investigated whether DCA induces nuclear factor-kappa B (NF-kappa B) activation and...
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Toxicity of Bile Acids on Colon Cancer Cell Lines

Park DK, Shin JH, Jun HJ, Kim KJ, Lee CY

  • KMID: 2175280
  • J Korean Cancer Assoc.
  • 1999 Feb;31(1):126-133.
PURPOSE: Cytotoxicity of the bile acids on colon cancer cell lines was studied to know which bile acid was most cytotoxic to colonic mucosal epithelium. We performed agarose gel electrophoresis...
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A Korean cancer patient with Trichosporon pullulans fungemia

Seo KW, Chung JW, Cho SY, Park BR, Lee MK

  • KMID: 2258381
  • Korean J Med.
  • 2009 Oct;77(4):527-530.
Trichosporon pullulans has recently been recognized as a human pathogen. Given its rarity, however, few reports describe infection attributable to this fungal pathogen. In immunocompromised hosts, T. pullulans infection is...
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Cytosolic Glutathione S-Transferase Change after Deoxycholate Exposure in Colon Cancer Cell Lines

Park DK, Shin JH, Park SG, Cheung SY

  • KMID: 1835108
  • J Korean Soc Coloproctol.
  • 1998 Dec;14(4):701-708.
PURPOSE: Bile acids (especially deoxycholate) was known to be toxic and mutagenic on colon epithelium. They proposed at least four mechanisms for the bile acid toxicity. It is the one...
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The Affinity of Calmodulin-Affigel for Inositol Triphosphate Kinase From Bovine Brain

Lim SW, Kim JH

The one event on signaling mechanism is the cleavage by adenyl cyclase of ATP into second messenger, cyclic AMP. The other transfer system of inositol metabolism, it is widely recognized...
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Two Cases of Candida inconspicua Infection in Neutropenic Patients with Acute Leukemia

Woo HY, Park SH, Lee DG, Jo HS, Min CK, Kim M, Han K, Shin WS

  • KMID: 2170177
  • Infect Chemother.
  • 2006 Jun;38(3):164-168.
Non-albicans Candida species which are resistant to azole are emerging as important pathogens in patients with hematological malignancies who received antifungal prophylaxis. C. inconspicua is one of rare Candida spp....
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Successful Treatment of Protothecal Tenosynovitis in an Immunocompetent Patient using Amphotericin B Deoxycholate

Kim JE, Oh TH, Lee KH, Shin JH, Jung SI

Protothecosis is an uncommon human infection caused by achlorophyllic algae of the genus Prototheca, especially P. wickerhamii. The skin is the most frequently involved organ and cases of protothecal tenosynovitis...
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Maxillary Sinusitis Caused by Mucormycosis

Ha YY, Lee SK, Park YW, Kim SG, Kim MK, Kim HY

  • KMID: 1960474
  • J Korean Assoc Maxillofac Plast Reconstr Surg.
  • 2013 Nov;35(6):432-436.
A 60-year-old male complained of headache, nasal discharge, and diplopia for over one month with a history of left upper molar extraction, and he had recently experienced severe discharge of...
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Visceral Leishmaniasis without Fever in an 11-Month-Old Infant: a Rare Clinical Feature of Kala-azar

Sayyahfar , Ansari S, Mohebali M, Behnam B

  • KMID: 1792167
  • Korean J Parasitol.
  • 2014 Apr;52(2):189-191.
Visceral leishmaniasis or kala-azar is an endemic parasitic disease in some parts of the world which is characterized by fever, splenomegaly, and pancytopenia in most of the cases. Herein we...
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