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A Case of Familial Creutzfeldt-Jacob Disease (V180I) Initially Presenting with Depression

Joo J, Yang Y, Kang JH, Lee SH, Ha SW, Han JH, Cho EK, Kim DE

Creutzfeldt-Jakob disease (CJD) is a degenerative neurological disorder that is incurable and invariably fatal. It is characterized by rapidly progressive dementia presenting with memory loss, personality changes and hallucinations. The...
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The Correlation of the White Matter Lesions and Lacunar Infarcts in Patients with Vascular Cognitive Impairment

Kim H, Jeong E, Juh R, Lee JH

BACKGROUND: Cerebral white matter lesions (WMLs) and lacunar infarcts (LIs) are mostly caused by small vessel disease (SVD). Whereas the main pathomechanism behind LIs is SVD, a variety of mechanisms...
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Subtypes of Amnestic Mild Cognitive Impairment Based on Memory Impairment Pattern and Its Potential Clinical Significance

Yang HD, Yang Y, Legesse BT, Kim S, Alzheimer's Disease Neuroimaging Initiative

BACKGROUND: Episodic memory impairment can be subdivided into two subtypes, encoding failure vs. retrieval deficit. We defined two subtypes of amnestic mild cognitive impairment (aMCI) according to recognition performance on...
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A Comparison on the Naming Abilities by Modality in Patients with Alzheimer's Disease

Kim H, Choi H

BACKGROUND: Impairments of language function represent patients with Alzheimer's disease (AD) from the early stage and as the disease progresses the damage spreads over a much broader range of cognition...
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Misfolded Proteins in Neurodegenerative Dementias: Molecular Mechanisms

Yang HD, Ho DH, Yi MJ, Seol W, Kim SY

During recent years, there has been remarkable progress with respect to the identification of molecular mechanisms and underlying pathology of neurodegenerative dementias. The latest evidence indicates that a common cause...
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Activities of Daily Living and Dementia

Yang Y, Yang HD, Hong YJ, Kim JE, Park MH, Na HR, Han IW, Kim S

Activities of daily living (ADL) refer to the ability to care for self and perform daily activities within an individual's place or in outdoor environments. ADL comprise two main categories:...
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