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Effect of intravenous deferoxamine in multiply transfused patients

Oh SM, Kang JW, Kim SY

PURPOSE: Multiple transfusions in patients with chronic anemia can result in excessive iron deposition in tissues and organs. Effective iron chelation therapy in chronically transfused patients can only be achieved...
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Efficacy of deferoxamine on paraquat poisoning

Huh JW, Jegal Y, Hong SB, Oh YM, Shim TS, Lim CM, Lee SD, Kim WS, Kim DS, Kim WD, Koh Y

BACKGROUND: Paraquat is known to induce oxidant injury that results in multiorgan failure and lung fibrosis. Iron has been considered to play a key role in paraquat-induced oxidant lung injury....
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The Expression of Hypoxia Inducible Factor-1alpha by Desferrioxamine Induces Radioresistance in Mouse Hepatoma Cell Line

Kwon BH

  • KMID: 1516698
  • J Korean Soc Ther Radiol Oncol.
  • 2004 Sep;22(3):217-224.
PURPOSE: It is well known that the radiosensitivity of tumor cells can be significantly reduced under hypoxic conditions. Hypoxia-inducible factor-1alpha (HIF-1alpha) plays a pivotal role in the essential adaptive responses...
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ReVersible Change of Vision in Patients Receiving Deferoxamine

Park MJ, Cho MS, Kim JS

  • KMID: 2206820
  • J Korean Ophthalmol Soc.
  • 2004 Aug;45(8):1397-1401.
PURPOSE: To report 2 cases of acute visual neurotoxicity in patients with paraquat poisoning receiving deferoxamine. METHODS: A 48-year-old woman and a 37-year-old man received intravenous infusion of deferoxamine at...
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Pathologic Scoring and Postoperative Liver Function in Canine Partial Liver Transplantation: after Desferrioxamine Exposure

Chung KY, Jeong GY, Kim YS

  • KMID: 2324345
  • J Korean Soc Transplant.
  • 2003 Dec;17(2):192-196.
PURPOSE: Liver biopsy plays an important role in the histopathological evaluation of the transplanted liver, but till now pretransplant graft biopsy has limited role in predicting primary non function of...
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Inhibitory effect of quercetin and desferrioxamine in rat reflux esophagitis

Song HJ, Kil BJ, Kim IW, Min YS, Kim DS, Sohn UD

  • KMID: 2071571
  • Korean J Physiol Pharmacol.
  • 2001 Aug;5(4):315-321.
This study was aimed to evaluate the effects of quercetin and desferrioxamine on the development of the reflux esophagitis induced surgically, on gastric secretion and on lipid peroxidation which is a marker of...
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The Antioxidant Effect of Vitamin C and Deferoxamine on Paraquat Induced Lipid Peroxidation in Rats

Jeong YK, Suh GJ, Jung JS, Jung SE, Choe KJ, Youn YK

  • KMID: 2100567
  • J Korean Soc Emerg Med.
  • 2000 Dec;11(4):421-436.
BACKGROUND: The toxicity of paraquat has been known to be caused by oxygen free radicals which leads to the lipid peroxidation and multiple organ failure. Although vitamin C has been...
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The Effects of Deferoxamine on the Oxygen Free Radical and Neutrophil in Ischemia-Reperfusion Injury

Yoo G, Hong SH, Wee SS, Chung SH, Han KT

  • KMID: 2119676
  • J Korean Soc Plast Reconstr Surg.
  • 2000 May;27(3):270-275.
Adequate circulation is indispensable for flap survival. Ischemia-reperfusion injury is one of the causes of flap necrosis. Current evidence suggests that tissue damage associated with ischemia-reperfusion injury and inflammatory responses may be...
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The Protective Effect of Vitamin E and Desferrioxamine on Cultured Cerebral Neurons of Neonatal Mouse Damaged by Ischemic Condition

Lee SR, Oh YK, Park ST

  • KMID: 2335458
  • J Korean Pediatr Soc.
  • 1999 Oct;42(10):1426-1433.
PURPOSE: Perinatal asphyxia is an important cause of neurologic morbidity. Experiments in animal models of hypoxic-ischemic brain injury demonstrate that brain damage starts during hypoxia-ischemia. In order to evaluate the...
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Effect of Desferrioxamine on Silica-Induced Cytotoxicity of A549 and Fibroblast Proliferation

Kim KA, Kim EK, Kim JH, Lim Y

  • KMID: 2028063
  • Korean J Occup Environ Med.
  • 1999 Jun;11(2):127-136.
The inhalation of crystalline silica results in the production of reactive oxygen species(ROS). Among these ROS, hydroxyl radical( OH) is believed to be the most reactive one. OH is generated...
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Deferoxamine Pretreatment Reduces Infarct Size of Acute Myocardial Infarction in a Rabbit Model

Yang KM, Oh DR, Park SH, Park KN, Lee WJ, Kim HK, Hwang DY, Choi SP, Chae JS

  • KMID: 2331235
  • J Korean Soc Emerg Med.
  • 1998 Dec;9(4):496-504.
BACKGROUND: Reperfusion of ischemic myocardium has been postulated to result in a specific oxygen radical mediated tissue injury. Iron may liberate during ischemia and we hypothesized that administration of the...
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Effect of Deferoxamine on Renal Function following Renal Ischemia/Reperfusion in the Rat

Bae IS, Jung HC, Park TC

  • KMID: 1881253
  • Korean J Urol.
  • 1998 Jul;39(7):615-621.
PURPOSE: It has been suggested in our previous study that the serum level of xanthine oxidise(XO) activity, glutathione(GSH), malonyldialdehyde(MDA) could be used as marker of oxidant stress in association with...
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Long-term Effect of Desferrioxamine to rHuEPO Regident Anemia in Hemodialysis Patients

Lim SW, Jung HJ, Bae SW, Do JY, Yoon KW

  • KMID: 2320337
  • Yeungnam Univ J Med.
  • 1997 Dec;14(2):399-414.
There are several factors concerning to anemia in chronic renal failure patients. But when rHuEPO is used, most of these factors can be overcome, and the levels of hemoglobin are...
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Effect of Desferrioxamine Therapy in Patients with Transfusional Hemosiderosis Due to Severe Aplastic Anemia

Lee JH, Cho B, Jeong DC, Kim HK

  • KMID: 2072455
  • Korean J Pediatr Hematol Oncol.
  • 1997 Apr;4(1):62-69.
BACKGROUND: This study was carried out to evaluate the efficacy of desferrioxamine as a chelating agent in iron overloaded patients with severe aplastic anemia due to multiple transfusion. METHODS AND MATERIALS:...
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The effect of desferrioxamine on cell cycle of human hepatoma cell lines

Kim DY, Kim WH, Kang JK, Park IS, Hong SK, Lee JW, Kwon OH

  • KMID: 2240754
  • Korean J Gastroenterol.
  • 1993 Dec;25(6):1224-1232.
No abstract available.
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The effect of desferrioxamine on DNA synthesis of human hepatoma cell lines

Kim DY, Kim WH, Song SY, Kang JK, Moon IH, Yoon KI

  • KMID: 2240753
  • Korean J Gastroenterol.
  • 1993 Dec;25(6):1218-1223.
No abstract available.
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Combined effect of desferrioxamine and anticancer durg on cultured gastric cancer cell

Kim WH, Lee KS, Moon YM, Kang JK, Park IS, Choi HJ, Kim HS, Kwon OH

  • KMID: 1685538
  • Korean J Gastroenterol.
  • 1993 Feb;25(1):46-60.
No abstract available.
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The Effect of Allopurinol and Deferoxamine on Postischemic Lipid Peroxidation

Kwon TH, Park YK, Chong YK, Chung HS, Suh JK, Lee HK, Chu JW, Lee KC

  • KMID: 2019515
  • J Korean Neurosurg Soc.
  • 1992 Jan;21(1):90-96.
It has been hypothesized that ischemia, followed by reperfusion, facilitates peroxidative free radical chain process in brain. This study was undertaken to investigate the effect of allopurinol and deferoxamine on...
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