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ReVersible Change of Vision in Patients Receiving Deferoxamine

Park MJ, Cho MS, Kim JS

  • KMID: 2206820
  • J Korean Ophthalmol Soc.
  • 2004 Aug;45(8):1397-1401.
PURPOSE: To report 2 cases of acute visual neurotoxicity in patients with paraquat poisoning receiving deferoxamine. METHODS: A 48-year-old woman and a 37-year-old man received intravenous infusion of deferoxamine at...
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Combined effect of desferrioxamine and anticancer durg on cultured gastric cancer cell

Kim WH, Lee KS, Moon YM, Kang JK, Park IS, Choi HJ, Kim HS, Kwon OH

  • KMID: 1685538
  • Korean J Gastroenterol.
  • 1993 Feb;25(1):46-60.
No abstract available.
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The effect of desferrioxamine on DNA synthesis of human hepatoma cell lines

Kim DY, Kim WH, Song SY, Kang JK, Moon IH, Yoon KI

  • KMID: 2240753
  • Korean J Gastroenterol.
  • 1993 Dec;25(6):1218-1223.
No abstract available.
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The effect of desferrioxamine on cell cycle of human hepatoma cell lines

Kim DY, Kim WH, Kang JK, Park IS, Hong SK, Lee JW, Kwon OH

  • KMID: 2240754
  • Korean J Gastroenterol.
  • 1993 Dec;25(6):1224-1232.
No abstract available.
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The Effects of Deferoxamine on the Oxygen Free Radical and Neutrophil in Ischemia-Reperfusion Injury

Yoo G, Hong SH, Wee SS, Chung SH, Han KT

  • KMID: 2119676
  • J Korean Soc Plast Reconstr Surg.
  • 2000 May;27(3):270-275.
Adequate circulation is indispensable for flap survival. Ischemia-reperfusion injury is one of the causes of flap necrosis. Current evidence suggests that tissue damage associated with ischemia-reperfusion injury and inflammatory responses may be...
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Efficacy of deferoxamine on paraquat poisoning

Huh JW, Jegal Y, Hong SB, Oh YM, Shim TS, Lim CM, Lee SD, Kim WS, Kim DS, Kim WD, Koh Y

BACKGROUND: Paraquat is known to induce oxidant injury that results in multiorgan failure and lung fibrosis. Iron has been considered to play a key role in paraquat-induced oxidant lung injury....
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Effect of intravenous deferoxamine in multiply transfused patients

Oh SM, Kang JW, Kim SY

PURPOSE: Multiple transfusions in patients with chronic anemia can result in excessive iron deposition in tissues and organs. Effective iron chelation therapy in chronically transfused patients can only be achieved...
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Deferoxamine Pretreatment Reduces Infarct Size of Acute Myocardial Infarction in a Rabbit Model

Yang KM, Oh DR, Park SH, Park KN, Lee WJ, Kim HK, Hwang DY, Choi SP, Chae JS

  • KMID: 2331235
  • J Korean Soc Emerg Med.
  • 1998 Dec;9(4):496-504.
BACKGROUND: Reperfusion of ischemic myocardium has been postulated to result in a specific oxygen radical mediated tissue injury. Iron may liberate during ischemia and we hypothesized that administration of the...
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Economic Evaluation of Iron Chelation Agents: Oral Deferasirox versus Infusional Deferoxamine

Kim JH, Kim YH

BACKGROUND: Patients with transfusional iron overload have relied on treatment with deferoxamine, a standard chelating agent. Deferoxamine is administered by intravenous or subcutaneous infusion over an 8~12 hour period 5~7...
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Effect of Iron-Chelator Deferiprone on the In Vitro Growth of Staphylococci

Kim CM, Shin SH

The standard iron-chelator deferoxamine is known to prevent the growth of coagulase-negative staphylococci (CoNS) which are major pathogens in iron-overloaded patients. However, we found that deferoxamine rather promotes the growth...
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Complete Hematopoietic Recovery after Continuous Iron Chelation Therapy in a Patient with Severe Aplastic Anemia with Secondary Hemochromatosis

Park SJ, Han CW

A 16-yr-old male patient with hemochromatosis due to multiple packed red blood cell transfusions was referred to our emergency center for the treatment of severe aplastic anemia and dyspnea. He...
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The Effect of Allopurinol and Deferoxamine on Postischemic Lipid Peroxidation

Kwon TH, Park YK, Chong YK, Chung HS, Suh JK, Lee HK, Chu JW, Lee KC

  • KMID: 2019515
  • J Korean Neurosurg Soc.
  • 1992 Jan;21(1):90-96.
It has been hypothesized that ischemia, followed by reperfusion, facilitates peroxidative free radical chain process in brain. This study was undertaken to investigate the effect of allopurinol and deferoxamine on...
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Iron chelating agent, deferoxamine, induced apoptosis in Saos-2 osteosarcoma cancer cells

Park EH, Lee HJ, Lee SY, Kim SY, Yi HK, Lee DY, Hwang PH

PURPOSE: Iron is a critical nutritional element that is essential for a variety of important biological processes, including cell growth and differentiation, electron transfer reactions, and oxygen transport, activation, and...
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The effect of erythropoietin in neonatal rat model of hypoxic-ischemic brain injury

Kim HM, Choe BH, Kwon SH, Sohn YK

PURPOSE: Perinatal asphyxia is an important cause of neonatal mortality and subsequent lifelong neurodevelopmental handicaps. Although many treatment strategies have been tested, there is currently no clinically effective treatment to...
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A Case of Gastric Injury by Acute Iron Intoxication

Lee JS, Chae HS, Chung WC, Kim SS, Song HJ, Choi SH, Kwon JA, Jun DH, Lee CD, Choi KY, Jung IS, Sun HS, Chung SK, Choi KH

  • KMID: 1929292
  • Korean J Gastrointest Endosc.
  • 2002 Feb;24(2):88-91.
Iron is a kind of corrosive agent. Iron overdose causes gastrointestinal complication such as mucosal ulceration, bleeding, intestinal perforation and may occur metabolic acidosis, hepatic dysfunction, hepatic failure, renal failure...
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The effect of deferoxamine on the preneoplastic lesions in the chemically induced hepatocarcinogenesis

Park YN, Jung WH, Park C

Iron is essential for the growth of all living cells. One of the most important intracellular roles of iron is the activation of ribonucleotide reductase, which is indispensible to the...
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A Case of Acute Aluminum Encephalopathy with Intraperitoneal Bladder Rupture Following Aluminum Bladder Irrigation in a Patient with Normal Renal Function

An YH, Kim SG, Park JY, Jang GS, Kim SY, Hong EY, An JS

  • KMID: 2263486
  • Korean J Med.
  • 2012 Aug;83(2):258-262.
Acute aluminum intoxication is uncommon in clinical practice but can be fatal. Most cases have been reported in patients with decreased renal function, especially dialysis patients. We describe a case...
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Effect of Deferoxamine on Renal Function following Renal Ischemia/Reperfusion in the Rat

Bae IS, Jung HC, Park TC

  • KMID: 1881253
  • Korean J Urol.
  • 1998 Jul;39(7):615-621.
PURPOSE: It has been suggested in our previous study that the serum level of xanthine oxidise(XO) activity, glutathione(GSH), malonyldialdehyde(MDA) could be used as marker of oxidant stress in association with...
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Acute Tubulointerstitial Nephritis Induced by Deferasirox following Hematopoietic Stem Cell Transplantation for Severe Aplastic Anemia

Min JW, Hwang SJ, Lim YJ, Lee YH

Deferasirox is a once-daily, oral iron-chelating agent that is now widely available for the treatment of transfusional hemosiderosis. Deferasirox represents a significant advance in the treatment of iron overload, as...
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The Antioxidant Effect of Vitamin C and Deferoxamine on Paraquat Induced Lipid Peroxidation in Rats

Jeong YK, Suh GJ, Jung JS, Jung SE, Choe KJ, Youn YK

  • KMID: 2100567
  • J Korean Soc Emerg Med.
  • 2000 Dec;11(4):421-436.
BACKGROUND: The toxicity of paraquat has been known to be caused by oxygen free radicals which leads to the lipid peroxidation and multiple organ failure. Although vitamin C has been...
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