- Improved immunogenicity of Newcastle disease virus inactivated vaccine following DNA vaccination using Newcastle disease virus hemagglutinin-neuraminidase and fusion protein genes
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Firouzamandi M, Moeini H, Hosseini D, Bejo MH, Omar AR, Mehrbod P, Ideris A
- KMID: 2363331
- J Vet Sci.
- 2016 Mar;17(1):21-26.
- doi: 10.4142/jvs.2016.17.1.21
The present study describes the development of DNA vaccines using the hemagglutinin-neuraminidase (HN) and fusion (F) genes from AF2240 Newcastle disease virus strain, namely pIRES/HN, pIRES/F and pIRES-F/HN. Transient expression... -
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- Enhanced immune response with foot and mouth disease virus VP1 and interleukin-1 fusion genes
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Park JH, Kim SJ, Oem JK, Lee KN, Kim YJ, Kye SJ, Park JY, Joo YS
- KMID: 1089910
- J Vet Sci.
- 2006 Sep;7(3):257-262.
- doi: 10.4142/jvs.2006.7.3.257
The capsid of the foot and mouth disease (FMD) virus carries the epitopes that are critical for inducing the immune response. In an attempt to enhance the specific immune response,... -
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- Detection of cryptic Y chromosome mosaicism by coamplification PCR with archived cytogenetic slides of suspected Turner syndrome
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Kim JW, Cho EH, Kim YM, Kim JM, Han JY, Park SY
- KMID: 927132
- Exp Mol Med.
- 2000 Mar;32(1):38-41.
Turner syndrome is one of the most common cytogenetic abnormalities. It is known that the Y chromosome or Y derived material is present in 6-9% of TS patient and it... -
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- Protective mechanism of glucose against alloxan-induced beta-cell damage: pivotal role of ATP
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Rho HW, Lee JN, Kim HR, Park BH, Park JW
- KMID: 927128
- Exp Mol Med.
- 2000 Mar;32(1):12-17.
Glucose prevents the development of diabetes induced by alloxan. In the present study, the protective mechanism of glucose against alloxan-induced beta-cell damage was investigated using HIT-T 15 cell, a Syrian... -
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- Hypoxia activates signal transducers and activators of transcription 5 (STAT5) and increases its binding activity to the GAS element in mammary epithelial cells
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Joung YH, Park JH, Park T, Lee CS, Kim OH, Ye SK, Yang UM, Lee KJ, Yang YM
- KMID: 1093606
- Exp Mol Med.
- 2003 Oct;35(5):350-357.
STATs (signal transducers and activators of transcription) are proteins with dual functions: signal transducers in the cytoplasm and transcriptional activators in the nucleus. STAT proteins act as transcription factors activated... -
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- Retroactive DNA analysis for sex determination and dystrophin gene by polymerase chain reaction with archived cytogenetic slides
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Choi SK, Kim JW, Park SY, Kim YM, Kim JM, Ryu HM, Yang JS, Yoon SR
- KMID: 755025
- Exp Mol Med.
- 1999 Mar;31(1):36-41.
We describe a rapid and efficient diagnostic method for sex determination and the dystrophin gene by the polymerase chain reaction (PCR) using archived cytogenetic slides. Archived cytogenetic slides stored for about 4... -
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- Molecular analysis of prion protein gene (PRNP) in Korean patients with Creutzfeldt-Jakob disease
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Jeong BH, Ju WK, Huh K, Lee EA, Choi IS, Im JH, Choi EK, Kim YS
- KMID: 1745544
- J Korean Med Sci.
- 1998 Jun;13(3):234-240.
- doi: 10.3346/jkms.1998.13.3.234
Creutzfeldt-Jakob disease (CJD), a relatively uncommon human dementia, is caused by an unconventional slow infectious agent. Several cases of CJD, clinically or histopathologically diagnosed, have been reported in Korea.... -
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- Emerging antimicrobial resistance, plasmid profile and pulsed-field gel electrophoresis pattern of the endonuclease-digested genomic DNA of Neisseria gonorrhoeae
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Lee K, Shin JW, Lim JB, Kim YA, Yong D, Oh HB, Chong Y
- KMID: 711761
- Yonsei Med J.
- 2000 Jun;41(3):381-386.
- doi: 10.3349/ymj.2000.41.3.381
Resistant gonococci are very prevalent in many countries, particularly in Asia. This study was conducted to determine the trend of resistance, the effect of decreasing the ciprofloxacin susceptibilities of gonococci... -
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- Loss of Heterozygosity and PCR Artifacts in a Microsatellite Analysis of Psoriasis and Colorectal Cancer
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Hyun JS, Jo BK, Park CJ, Yi JY, Lee JY, Rhyu MG
- KMID: 1127256
- J Korean Med Sci.
- 2002 Oct;17(5):641-647.
- doi: 10.3346/jkms.2002.17.5.641
Although a loss of heterozygosity (LOH) is commonly observed using microsatellite markers in a cell-proliferating malignant disorder, controversial findings of psoriasis, a keratinocyte-outgrowth disease, remain to be explained. It... -
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- Decreased expression of DNA repair proteins Ku70 and Mre11 is associated with aging and may contribute to the cellular senescence
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Ju YJ, Lee KH, Park JE, Yi YS, Yun MY, Ham YH, Kim TJ, Choi HM, Han GJ, Lee JH, Lee J, Han JS, Lee KM, Park GH
- KMID: 1115947
- Exp Mol Med.
- 2006 Dec;38(6):686-693.
The gradual loss of telomeric DNA can contribute to replicative senescence and thus, having longer telomeric DNA is generally considered to provide a longer lifespan. Maintenance and stabilization of telomeric... -
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- Point Mutation of Hoxd12 in Mice
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Cho KW, Kim JY, Cho JW, Cho KH, Song CW, Jung HS
- KMID: 1782945
- Yonsei Med J.
- 2008 Dec;49(6):965-972.
- doi: 10.3349/ymj.2008.49.6.965
PURPOSE: Genes of the HoxD cluster play a major role in vertebrate limb development, and changes that modify the Hoxd12 locus affect other genes also, suggesting that HoxD function is... -
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- GSTM1, GSTT1 and GSTP1 Polymorphisms in the Korean Population
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Cho HJ, Lee SY, Ki CS, Kim JW
- KMID: 2157771
- J Korean Med Sci.
- 2005 Dec;20(6):1089-1092.
- doi: 10.3346/jkms.2005.20.6.1089
The isoenzymes of the glutathione s transferase (GST) family play a vital role in phase II of biotransformation of many substances. Using a multiplex polymerase chain reaction and a direct... -
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- Two Novel Mutations in the Aquaporin 2 Gene in a Girl with Congenital Nephrogenic Diabetes Insipidus
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Cheong HI, Cho SJ, Zheng SH, Cho HY, Ha IS, Choi Y
- KMID: 2157767
- J Korean Med Sci.
- 2005 Dec;20(6):1076-1078.
- doi: 10.3346/jkms.2005.20.6.1076
Congenital nephrogenic diabetes insipidus (CNDI) is a rare inherited disorder characterized by insensitivity of the kidney to the antidiuretic effect of vasopressin. There are three inheritance patterns of CNDI: the... -
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- Interleukin-10 Promoter Polymorphism is Associated with the Predisposition to the Development of IgA Nephropathy and Focal Segmental Glomerulosclerosis in Korea
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Chin HJ, Na KY, Kim SJ, Oh KH, Kim YS, Lim CS, Kim S, Chae DW
- KMID: 2157750
- J Korean Med Sci.
- 2005 Dec;20(6):989-993.
- doi: 10.3346/jkms.2005.20.6.989
The roles of interleukin-10 (IL-10) have been emphasized in several models of glomerulonephritis (GN). Three biallelic polymorphisms within the IL-10 promoter region, at positions -1,082, -819, and -592 from the... -
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- Angiotensin-Converting Enzyme Gene Insertion/Deletion Polymorphism in Korean Patients with Systemic Sclerosis
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Joung CI, Park YW, Kim SK, Uhm WS, Kim TH, Yoo DH
- KMID: 1781844
- J Korean Med Sci.
- 2006 Apr;21(2):329-332.
- doi: 10.3346/jkms.2006.21.2.329
To determine whether angiotensin-converting enzyme (ACE) gene insertion/deletion (I/D) polymorphism is associated with the development and clinical features of systemic sclerosis (SSc) in Korean, we studied seventy two Korean patients... -
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- A Case of Neonatal Alloimmune Neutropenia Associated with Anti-Human Neutrophil Antigen-1a (HNA-1a) Antibody
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Han TH, Chey MJ, Han KS
- KMID: 1781849
- J Korean Med Sci.
- 2006 Apr;21(2):351-354.
- doi: 10.3346/jkms.2006.21.2.351
Neonatal alloimmune neutropenia (NAN) is an uncommon disease of the newborn provoked by the maternal production of neutrophil-specific alloantibodies, whereby neutrophil IgG antibodies cross the placenta and induce the destruction... -
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- Sequence variations of the bovine prion protein gene (PRNP) in native Korean Hanwoo cattle
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Choi S, Woo HJ, Lee J
- KMID: 1376186
- J Vet Sci.
- 2012 Jun;13(2):127-137.
- doi: 10.4142/jvs.2012.13.2.127
Bovine spongiform encephalopathy (BSE) is one of the fatal neurodegenerative diseases known as transmissible spongiform encephalopathies (TSEs) caused by infectious prion proteins. Genetic variations correlated with susceptibility or resistance to... -
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- Association of Vitamin D Receptor Gene Polymorphism and Parkinson's Disease in Koreans
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Kim JS, Kim YI, Song C, Yoon I, Park JW, Choi YB, Kim HT, Lee KS
- KMID: 1778513
- J Korean Med Sci.
- 2005 Jun;20(3):495-498.
- doi: 10.3346/jkms.2005.20.3.495
1alpha,25-dihydroxyvitamin D3 (1,25(OH)2D3), which is the biologically active form of vitamin D, has anti-inflammatory effects and can prevent experimental Parkinson's disease (PD). 1,25(OH)2D3 exerts most of its actions only after... -
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- Genetic variability of six indigenous goat breeds using major histocompatibility complex-associated microsatellite markers
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Salles P, Santos SC, Rondina D, Weller M
- KMID: 1106554
- J Vet Sci.
- 2011 Jun;12(2):127-132.
- doi: 10.4142/jvs.2011.12.2.127
The present study aimed at analyzing the genetic variability of indigenous goat breeds (Capra hircus) using the MHC-associated microsatellite markers BF1, BM1818, BM1258, DYMS1, and SMHCC1. The following breeds were... -
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- Common variants at the promoter region of the APOM confer a risk of rheumatoid arthritis
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Hu HJ, Jin EH, Yim SH, Yang SY, Jung SH, Shin SH, Kim WU, Shim SC, Kim TG, Chung YJ
- KMID: 1025164
- Exp Mol Med.
- 2011 Nov;43(11):613-621.
- doi: 10.3858/emm.2011.43.11.068
Although the genetic component in the etiology of rheumatoid arthritis (RA) has been consistently suggested, many novel genetic loci remain to uncover. To identify RA risk loci, we performed a... -
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