- New Insight for HBV DNA and HBsAg Quantitation during Antiviral Therapy in Patients with Chronic Hepatitis B
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Cho YK, Song BC
- KMID: 1128352
- Korean J Gastroenterol.
- 2011 Mar;57(3):144-149.
- doi: 10.4166/kjg.2011.57.3.144
Over the past decade, advances in the antiviral therapy in patients with chronic hepatitis B have enabled the sustained suppression of hepatitis B viral replication and the prevention of progressive... -
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- Comparison of Quantitation of Cytomegalovirus DNA by Real-Time PCR in Whole Blood with the Cytomegalovirus Antigenemia Assay
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Kwon S, Jung BK, Ko SY, Lee CK, Cho Y
- KMID: 2363155
- Ann Lab Med.
- 2015 Jan;35(1):99-104.
- doi: 10.3343/alm.2015.35.1.99
BACKGROUND: Quantitation of cytomegalovirus (CMV) DNA using real-time PCR has been utilized for monitoring CMV infection. However, the CMV antigenemia assay is still the 'gold standard' assay. There are only... -
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- Significance of Epstein-Barr Virus DNA Quantitation in Donors of Hematopoietic Stem Cell Transplantation
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Jung S, Lim J, Cho BS, Chae H, Kim M, Kim Y, Han K, Lee JW, Min WS
- KMID: 1781658
- Korean J Lab Med.
- 2010 Dec;30(6):554-558.
- doi: 10.3343/kjlm.2010.30.6.554
BACKGROUND: Epstein-Barr virus (EBV) is a well-known causative agent of various diseases including post-transplant lymphoproliferative disorders. Although the level of EBV viral load in donors is expected to have a... -
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- Investigation of the Prevalence of Human Parvovirus B19 DNA in Korean Plasmapheresis Donors
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Oh DJ, Lee YL, Kang JW, Kwon SY, Cho NS
- KMID: 1096820
- Korean J Lab Med.
- 2010 Feb;30(1):58-64.
- doi: 10.3343/kjlm.2010.30.1.58
BACKGROUND: To ensure the safety of plasma derivatives, some countries have been screening for the human parvovirus B19 (B19V) antigen or DNA in blood donors. We investigated the prevalence of... -
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- Serum ALT and HBV DNA Levels in Patients with HBeAg-Negative Chronic Hepatitis B
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Kim KH, Na IH, Cha JM, Cho YK, Park SY, Kim HP, Song CS, Heo J, Cho M
- KMID: 1085301
- Korean J Hepatol.
- 2003 Dec;9(4):284-292.
BACKGROUND/AIMS: HBeAg-negative chronic hepatitis B (CHB) has a poor long-term prognosis. Since no precise clinically relevant HBV thresholds are known in HBeAg-negative CHB, the decision to treat is difficult.... -
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- Performance of the Real-Q EBV Quantification Kit for Epstein-Barr Virus DNA Quantification in Whole Blood
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Huh HJ, Park JE, Kim JY, Yun SA, Lee MK, Lee NY, Kim JW, Ki CS
- KMID: 2373632
- Ann Lab Med.
- 2017 Mar;37(2):147-150.
- doi: 10.3343/alm.2017.37.2.147
There has been increasing interest in standardized and quantitative Epstein-Barr virus (EBV) DNA testing for the management of EBV disease. We evaluated the performance of the Real-Q EBV Quantification Kit... -
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- Hepatitis B Surface Antigen Quantification across Different Phases of Chronic Hepatitis B Virus Infection Using an Immunoradiometric Assay
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Chung KH, Kim W, Kim BG, Lee HY, Jin E, Cho Y, Seo JY, Kim HY, Jung YJ, Kim JW, Jeong JB, Lee KL
- KMID: 2234073
- Gut Liver.
- 2015 Sep;9(5):657-664.
- doi: 10.5009/gnl14188
BACKGROUND/AIMS: Quantification of hepatitis B surface antigen (HBsAg) is an emerging serologic test and may be useful for identifying treatment strategies for chronic hepatitis B (CHB). This study aimed to... -
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- Change of HBV DNA Level as a Predictor of HBeAg Loss after Lamivudine Treatment
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Jung JK, Lee CH, Kim EY, Jung JT, Choi JH, Han JM, Jin MI, Cho JY, Kim BS, Shin IH
- KMID: 1776827
- Korean J Hepatol.
- 2007 Dec;13(4):513-520.
- doi: 10.3350/kjhep.2007.13.4.513
BACKGROUND AND AIMS: Lamivudine is an effective, safe therapeutic agent for the treatment of chronic hepatitis B. The aim of this study was to investigate whether early suppression of... -
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- Occult HBV among Anti-HBc Alone: Mutation Analysis of an HBV Surface Gene and Pre-S Gene
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Kim MH, Kang SY, Lee WI
- KMID: 2419113
- Yonsei Med J.
- 2017 May;58(3):557-563.
- doi: 10.3349/ymj.2017.58.3.557
PURPOSE: The aim of this study is to investigate the molecular characteristics of occult hepatitis B virus (HBV) infection in ‘anti-HBc alone’ subjects. MATERIALS AND METHODS: Twenty-four patients with ‘anti-HBc alone’... -
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- Continuous Long-Term Entecavir Therapy in Naive Chronic Hepatitis B Patients Showing Partial Virologic Response
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Kwon DH, Kim IH, Choung BS, Ahn DS, Yoo SH, Park SB, Lee S, Kim SH, Kim SW, Im YJ
- KMID: 1712332
- Gut Liver.
- 2013 Nov;7(6):712-718.
BACKGROUND/AIMS: We investigated the efficacy of continuous long-term entecavir 0.5 mg treatment in naive chronic hepatitis B patients showing a partial virologic response (PVR). METHODS: A total of 227 patients were... -
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- Performance Evaluation of the Real-Q Cytomegalovirus (CMV) Quantification Kit Using Two Real-Time PCR Systems for Quantifying CMV DNA in Whole Blood
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Park JE, Kim JY, Yun SA, Lee MK, Huh HJ, Kim JW, Ki CS
- KMID: 2373601
- Ann Lab Med.
- 2016 Nov;36(6):603-606.
- doi: 10.3343/alm.2016.36.6.603
Standardized cytomegalovirus (CMV) DNA quantification is important for managing CMV disease. We evaluated the performance of the Real-Q CMV Quantification Kit (Real-Q assay; BioSewoom, Korea) using whole blood (WB), with... -
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- Automated Nucleic Acid Extraction Systems for Detecting Cytomegalovirus and Epstein-Barr Virus Using Real-Time PCR: A Comparison Study Between the QIAsymphony RGQ and QIAcube Systems
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Kim H, Hur M, Kim JY, Moon HW, Yun YM, Cho HC
- KMID: 2373630
- Ann Lab Med.
- 2017 Mar;37(2):129-136.
- doi: 10.3343/alm.2017.37.2.129
BACKGROUND: Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are increasingly important in immunocompromised patients. Nucleic acid extraction methods could affect the results of viral nucleic acid amplification tests. We compared two... -
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- Pretreatment serum HBsAg-to-HBV DNA ratio predicts a virologic response to entecavir in chronic hepatitis B
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Song JC, Min BY, Kim JW, Kim JY, Kim YM, Shin CM, Lee SH, Hwang JH, Jeong SH, Kim N, Lee DH
- KMID: 1792605
- Korean J Hepatol.
- 2011 Dec;17(4):268-273.
- doi: 10.3350/kjhep.2011.17.4.268
BACKGROUND/AIMS: Decay of hepatitis B surface antigen (HBsAg) titers has previously been shown to be predictive of a virologic response (VR), especially during peginterferon-alpha therapy. However, the role of HBsAg... -
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- Relationship between Serum HBV DNA Levels and Liver Histology in Chronic Hepatitis B
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Heo JH, Heo J, Kwon DS, Moon JH, Kim GH, Kang DH, Song GA, Cho M, Yang US
- KMID: 881586
- Korean J Gastroenterol.
- 2003 Sep;42(3):220-225.
BACKGROUND/AIMS: Serum HBV DNA levels are correlated with hepatic histologic activity in chronic HBV infection based on HBeAg. Liver injury may persist, even though HBV DNA are not detected by... -
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- Performance Evaluation of Abbott RealTime HBV Quantification Kit for HBV Viral Load by Real-Time PCR
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Kim MH, Cha CH, An D, Choi SE, Oh HB
- KMID: 854849
- Korean J Lab Med.
- 2008 Apr;28(2):144-150.
- doi: 10.3343/kjlm.2008.28.2.144
BACKGROUND: Hepatitis B virus (HBV) DNA quantification is necessary for starting and monitoring of antiviral therapy in patients with chronic hepatitis B. This study was intended to assess the... -
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- Comparison of Quantitative Cytomegalovirus Real-time PCR in Whole Blood and pp65 Antigenemia Assay: Clinical Utility of CMV Real-time PCR in Hematopoietic Stem Cell Transplant Recipients
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Choi SM, Lee DG, Lim J, Park SH, Choi JH, Yoo JH, Lee JW, Kim Y, Han K, Min WS, Shin WS, Kim CC
- KMID: 1779186
- J Korean Med Sci.
- 2009 Aug;24(4):571-578.
- doi: 10.3346/jkms.2009.24.4.571
Successful preemptive therapy for cytomegalovirus (CMV) infection in transplant patients depends on the availability of sensitive, specific, and timely diagnostic tests for CMV infection. Although the pp65 antigenemia assay has... -
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