- Next generation sequencing and urologic cancer
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Kim SK, Kim WJ
- KMID: 2133271
- Korean J Urol.
- 2015 Feb;56(2):87-89.
- doi: 10.4111/kju.2015.56.2.87
No abstract available. -
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- Value of urinary topoisomerase-IIA cell-free DNA for diagnosis of bladder cancer
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Kim YH, Yan C, Lee IS, Piao XM, Byun YJ, Jeong P, Kim WT, Yun SJ, Kim WJ
- KMID: 2363132
- Investig Clin Urol.
- 2016 Mar;57(2):106-112.
- doi: 10.4111/icu.2016.57.2.106
PURPOSE: Topoisomerase-II alpha (TopoIIA ), a DNA gyrase isoform that plays an important role in the cell cycle, is present in normal tissues and various human cancers, and can show... -
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- Regulation of bcl-2 family in hydrogen peroxide-induced apoptosis in human leukemia HL-60 cells
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Lee JE, Sohn JW, Lee JH, Lee KC, Son CS, Tockgo YC
- KMID: 927133
- Exp Mol Med.
- 2000 Mar;32(1):42-46.
Numerous types of cells have been shown to undergo apoptosis when exposed to oxidant agent such as hydrogen peroxide. In order to understand the functional relationship between the anti- and... -
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- Clinicopathological Characteristics of Colorectal Cancer with Family History: an Evaluation of Family History as a Predictive Factor for Microsatellite Instability
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Park IJ, Kim HC, Yoon YS, Yu CS, Jang SJ, Kim JC
- KMID: 1785795
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S91-S97.
- doi: 10.3346/jkms.2007.22.S.S91
To determine whether family history of cancer may be a risk factor for the mutator phenotype in colorectal cancer, we recruited 143 consecutive colorectal cancer patients with a family history... -
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- Decreased Expression of 15-hydroxyprostaglandin Dehydrogenase in Gastric Carcinomas
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Jang TJ, Ji YS, Jung KH
- KMID: 1782939
- Yonsei Med J.
- 2008 Dec;49(6):917-922.
- doi: 10.3349/ymj.2008.49.6.917
PURPOSE: Gastric carcinoma tissues release high level of prostaglandin E2 (PGE2) when compared to non-neoplastic mucosa, and cyclooxygenase-2 (COX-2), which is the rate-limiting enzyme in prostaglandin (PG) biosynthesis, is often... -
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- Loss of heterozygosity on chromosome XP22.2-p22.13 and Xq26.1-q27.1 in human breast carcinomas
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Choi C, Kim MH, Juhng SW
- KMID: 1745556
- J Korean Med Sci.
- 1998 Jun;13(3):311-316.
- doi: 10.3346/jkms.1998.13.3.311
In an attempt to investigate the X chromosome harboring putative tumor suppressor genes (TSGs) in sporadic breast carcinoma, we performed loss of heterozygosity (LOH) studies on 23 breast carcinomas... -
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- Loss of Heterozygosity and PCR Artifacts in a Microsatellite Analysis of Psoriasis and Colorectal Cancer
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Hyun JS, Jo BK, Park CJ, Yi JY, Lee JY, Rhyu MG
- KMID: 1127256
- J Korean Med Sci.
- 2002 Oct;17(5):641-647.
- doi: 10.3346/jkms.2002.17.5.641
Although a loss of heterozygosity (LOH) is commonly observed using microsatellite markers in a cell-proliferating malignant disorder, controversial findings of psoriasis, a keratinocyte-outgrowth disease, remain to be explained. It... -
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- A clinicogenetic model to predict lymph node invasion by use of genome-based biomarkers from exome arrays in prostate cancer patients
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Oh JJ, Park S, Lee SE, Hong SK, Lee S, Lee HM, Lee JK, Ho JN, Yoon S, Byun SS
- KMID: 2133274
- Korean J Urol.
- 2015 Feb;56(2):109-116.
- doi: 10.4111/kju.2015.56.2.109
PURPOSE: Genetic variations among prostate cancer (PCa) patients who underwent radical prostatectomy (RP) and pelvic lymph node dissection were evaluated to predict lymph node invasion (LNI). Exome arrays were used... -
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- Downregulation of the RUNX3 Gene by Promoter Hypermethylation and Hemizygous Deletion in Breast Cancer
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Hwang KT, Han W, Bae JY, Hwang SE, Shin HJ, Lee JE, Kim SW, Min HJ, Noh DY
- KMID: 1785785
- J Korean Med Sci.
- 2007 Sep;22(Suppl):S24-S31.
- doi: 10.3346/jkms.2007.22.S.S24
The RUNX3 gene is regarded as a tumor suppressor gene in many human solid tumors, and its inactivation is believed to be related with solid tumor carcinogenesis. As little information... -
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- Clinical Significance of Microsatellite Instability in Sporadic Epithelial Ovarian Tumors
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Yoon BS, Kim YT, Kim JH, Kim SW, Nam EJ, Cho NH, Kim JW, Kim S
- KMID: 1084501
- Yonsei Med J.
- 2008 Apr;49(2):272-278.
- doi: 10.3349/ymj.2008.49.2.272
PURPOSE: We evaluated the expression of microsatellite instability (MSI) in sporadic ovarian tumors using 5 standard and 9 new MSI markers to determine the clinical significance of MSI in sporadic... -
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