- New insight on immune tolerance from transgenic mouse models
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Lee MS
- KMID: 932124
- J Korean Med Sci.
- 1996 Feb;11(1):1-7.
- doi: 10.3346/jkms.1996.11.1.1
No abstract available. -
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- Expression of Th1 and Th2 type cytokines responding to HBsAg and HBxAg in chronic hepatitis B patients
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Lee M, Lee MA, Lee SK, Son M, Cho SW, Park S, Kim HI
- KMID: 648077
- J Korean Med Sci.
- 1999 Apr;14(2):175-181.
- doi: 10.3346/jkms.1999.14.2.175
The cytokine pattern on viral antigen recognition is believed to exert a profound influence on the resolution of viral infections and viral clearance. This study was initiated to investigate whether... -
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- Hyperoxia influences mRNA expression of cytokines in cultured human umbilical vein endothelial cells
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Park MS, Wallace HM
- KMID: 711520
- Yonsei Med J.
- 1998 Feb;39(1):1-12.
- doi: 10.3349/ymj.1998.39.1.1
High concentrations of oxygen, indispensable for the treatment of severe hypoxemia from neonatal as well as adult respiratory distress syndrome, increase the risk of oxygen toxicity. Biochemical mechanisms are lipid... -
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- T Regulatory Cell Responses to Immunization with a Soluble Egg Antigen in Schistosoma mansoni-Infected Mice
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El-Ahwany , Bauiomy I, Nagy F, Zalat R, Mahmoud O, Zada S
- KMID: 1364892
- Korean J Parasitol.
- 2012 Mar;50(1):29-35.
- doi: 10.3347/kjp.2012.50.1.29
The aim of the study is to characterize the phenotypes of CD4+ CD25+ T regulatory cells within the liver granulomas and association with both Foxp-3 gene expression and splenic cytokines.... -
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- Nuclear factor kappaB (NF-kappaB) pathway as a therapeutic target in rheumatoid arthritis
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Jue DM, Jeon KI, Jeong JY
- KMID: 646299
- J Korean Med Sci.
- 1999 Jun;14(3):231-238.
- doi: 10.3346/jkms.1999.14.3.231
Rheumatoid arthritis (RA) is a chronic inflammatory disease characterized by persistent joint swelling and progressive destruction of cartilage and bone. Current RA treatments are largely empirical in origin and their... -
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- Comparison of Cytokine Expression in Mesenchymal Stem Cells from Human Placenta, Cord Blood, and Bone Marrow
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Hwang JH, Shim SS, Seok OS, Lee HY, Woo SK, Kim BH, Song HR, Lee JK, Park YK
- KMID: 1779182
- J Korean Med Sci.
- 2009 Aug;24(4):547-554.
- doi: 10.3346/jkms.2009.24.4.547
Mesenchymal stem cells (MSCs) are capable of self-renewal and differentiation into lineages of mesenchymal tissues that are currently under investigation for a variety of therapeutic applications. The purpose of this... -
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- Phenotypic and functional analysis of bovine gammadelta lymphocytes.
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Park YH, Yoo HS, Yoon JW, Yang SJ, An JS, Davis WC
- KMID: 1103473
- J Vet Sci.
- 2000 Jun;1(1):39-48.
The studies have provided the first comprehensive comparison of the factors regulating activation and proliferation of WC1+ and WC1- gammadelta T cells. The investigation has shown that accessory molecules essential... -
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- Applications of systems approaches in the study of rheumatic diseases
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Kim KJ, Lee S, Kim WU
- KMID: 2160677
- Korean J Intern Med.
- 2015 Mar;30(2):148-160.
- doi: 10.3904/kjim.2015.30.2.148
The complex interaction of molecules within a biological system constitutes a functional module. These modules are then acted upon by both internal and external factors, such as genetic and environmental... -
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- Age-Related CD4+CD25+Foxp3+ Regulatory T-Cell Responses During Plasmodium berghei ANKA Infection in Mice Susceptible or Resistant to Cerebral Malaria
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Shan Y, Liu J, Pan YY, Jiang YJ, Shang H, Cao YM
- KMID: 1715702
- Korean J Parasitol.
- 2013 Jun;51(3):289-295.
- doi: 10.3347/kjp.2013.51.3.289
Different functions have been attributed to CD4+CD25+Foxp3+ regulatory T-cells (Tregs) during malaria infection. Herein, we describe the disparity in Treg response and pro- and anti-inflammatory cytokines during infection with Plasmodium... -
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- The Effects of Intradermal Vaccination with DNA Encoding for the T-cell Receptor on the Induction of Experimental Autoimmune Encephalomyelitis in B10.PL Mice
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Kwon SS, Kim N, Yoo TJ
- KMID: 2157759
- J Korean Med Sci.
- 2005 Dec;20(6):1039-1045.
- doi: 10.3346/jkms.2005.20.6.1039
Intradermal gene administration was found to induce a more profound immune response than direct intramusclular gene injection. We performed intradermal vaccination of B10.PL mice with DNA encoding for the V... -
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- Berberine reduces the expression of adipogenic enzymes and inflammatory molecules of 3T3-L1 adipocyte
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Choi BH, Ahn IS, Kim YH, Park JW, Lee SY, Hyun CK, Do MS
- KMID: 1115937
- Exp Mol Med.
- 2006 Dec;38(6):599-605.
Berberine (BBR), an isoquinoline alkaloid, has a wide range of pharmacological effects, yet its exact mechanism is unknown. In order to understand the anti-adipogenic effect of BBR, we studied the... -
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- Trichinella spiralis Infection Suppressed Gut Inflammation with CD4+CD25+Foxp3+ T Cell Recruitment
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Cho MK, Park MK, Kang SA, Choi SH, Ahn SC, Yu HS
- KMID: 1792137
- Korean J Parasitol.
- 2012 Dec;50(4):385-390.
In order to know the effect of pre-existing Trichinella spiralis infection on experimentally induced intestinal inflammation and immune responses, we induced colitis in T. spiralis-infected mice and observed the severity... -
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- Nitric oxide suppresses inducible nitric oxide synthase expression by inhibiting post-translational modification of I kappa B
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Chang K, Lee SJ, Cheong I, Billiar TR, Chung HT, Han JA, Kwon YG, Ha KS, Kim YM
- KMID: 1094075
- Exp Mol Med.
- 2004 Aug;36(4):311-324.
The expression of inducible nitric oxide synthase (iNOS) is a critical factor in both normal physiological functions and the pathogenesis of disease. This study was undertaken to determine the molecular... -
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- What is the Most Important Factor for Gastric Carcinogenesis in Koreans: Helicobacter pylori, Host Factor or Environmental Factor?
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Kim HY
- KMID: 935181
- Korean J Gastroenterol.
- 2007 Feb;49(2):60-71.
Epidemiological data including our studies demonstrated the association between Helicobacter pylori (H. pylori) infection and gastric cancer. However, this significant clinical outcome happens only in a small portion of infected... -
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- Changes of Gene Expression after Bone Marrow Cell Transfusion in Rats with Monocrotaline-Induced Pulmonary Hypertension
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Kim KC, Lee HR, Kim SJ, Cho MS, Hong YM
- KMID: 1421611
- J Korean Med Sci.
- 2012 Jun;27(6):605-613.
- doi: 10.3346/jkms.2012.27.6.605
Pulmonary artery hypertension (PAH) causes right ventricular failure and possibly even death by a progressive increase in pulmonary vascular resistance. Bone marrow-derived mesenchymal stem cell therapy has provided an alternative... -
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- Protective effect of lectin from Synadenium carinatum on Leishmania amazonensis infection in BALB/c mice
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Afonso-Cardoso SR, Rodrigues , Gomes MA, Silva AG, Rocha A, Guimaraes , Candeloro , Favoreto S, Ferreira M, Souza MA
- KMID: 1089946
- Korean J Parasitol.
- 2007 Dec;45(4):255-266.
- doi: 10.3347/kjp.2007.45.4.255
The protective effect of the Synadenium carinatum latex lectin (ScLL), and the possibility of using it as an adjuvant in murine model of vaccination against American cutaneous leishmaniasis, were evaluated.... -
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- Prevalence and Clinical Characterization of Gastric Helicobacter Species Infection of Dogs and Cats in Korea
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Hwang CY, Han HR, Youn HY
- KMID: 1095371
- J Vet Sci.
- 2002 Jun;3(2):123-133.
This study was carried out to evaluate the prevalence and clinical characterizations of gastric Helicobacter spp. infection of dogs and cats in Korea. The prevalence of Helicobacter spp. infection of... -
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- Direct and Indirect Effects of Androgens on Survival of Hematopoietic Progenitor Cells In Vitro
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Kim SW, Hwang JH, Cheon JM, Park NS, Park SE, Park SJ, Yun HJ, Kim S, Jo DY
- KMID: 1778498
- J Korean Med Sci.
- 2005 Jun;20(3):409-416.
- doi: 10.3346/jkms.2005.20.3.409
Androgens remain a common treatment for certain type of anemia, based upon its myelostimulating effects; however, it has not been established whether androgens affect apoptosis of hematopoietic progenitor cells (HPCs).... -
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- Negative-pressure wound therapy induces endothelial progenitor cell mobilization in diabetic patients with foot infection or skin defects
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Seo SG, Yeo JH, Kim JH, Kim JB, Cho TJ, Lee DY
- KMID: 2154281
- Exp Mol Med.
- 2013 Nov;45(11):e62.
Non healing chronic wounds are difficult to treat in patients with diabetes and can result in severe medical problems for these patients and for society. Negative-pressure wound therapy (NPWT) has... -
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- Peroxisome proliferator-activated receptor delta agonist attenuates hepatic steatosis by anti-inflammatory mechanism
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Lee MY, Choi R, Kim HM, Cho EJ, Kim BH, Choi YS, Naowaboot , Lee EY, Yang YC, Shin JY, Shin YG, Chung CH
- KMID: 1506221
- Exp Mol Med.
- 2012 Oct;44(10):578-585.
Although peroxisome proliferator receptor (PPAR)-alpha and PPAR-gamma agonist have been developed as chemical tools to uncover biological roles for the PPARs such as lipid and carbohydrate metabolism, PPAR-delta has not... -
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