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The effect of verapamil on cysteamine-induced duodenal ulcer in the rat

Lee CK, Yim DS, Kim WH

To determine the effect of verapamil on experimental duodenal ulcer, pathologic assessment and secretory study were performed in the rats with ulcerogenic dose of cysteamine. The cysteamine increased gastric...
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Different inhibition characteristics of intracellular transglutaminase activity by cystamine and cysteamine

Jeon JH, Lee HJ, Jang GY, Kim CW, Shin DM, Cho SY, Yeo EJ, Park SC, Kim IG

  • KMID: 1103326
  • Exp Mol Med.
  • 2004 Dec;36(6):576-581.
The treatment of cystamine, a transglutaminase (TGase) inhibitor, has beneficial effects in several diseases including CAG-expansion disorders and cataract. We compared the inhibition characteristics of cystamine with those of cysteamine,...
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The Effect of Cysteamine on the Radiation-Induced Apoptosis

Choi YM, Park CG, cho HL, Lee HS, Hur WJ

  • KMID: 2097150
  • J Korean Soc Ther Radiol Oncol.
  • 2000 Sep;18(3):214-219.
PURPOSE: To investigate the pathways of radiation induced apoptosis and the effect of cysteamine (beta-mercaptoethylamine), as a radioprotector, on it. MATERIALS AND METHODS: HL-60 cells were assigned to control, irradiated, and...
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Exogenous cysteamine increases basal pancreatic exocrine secretion in the rat

Lee HS, Kim KH, Kim CD, Song CW, Ryu HS, Hyun JH

To determine whether exocrine pancreatic secretion is regulated by endogenous somatostatin, somatostatin deficiency was induced by cysteamine. Rats were subcutaneously administered a single dose of cysteamine (30 mg/100 g body ...
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Endocrine complications during and after adolescence in a patient with cystinosis

Ahn MB, Kim SE, Cho WK, Jung MH, Suh BK

Cystinosis is a rare disease characterized by abnormal lysosomal cystine accumulation of cystine due to impaired lysosomal transport. We previously reported the first case of cystinosis in Korea in a...
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Inhibition of intimal hyperplasia by local perivascular application of rapamycin and imatinib mesilate after carotid balloon injury

Park D, Kim SM, Min SI, Ha J, Kim IG, Min SK

PURPOSE: Inhibition of the intimal hyperplasia after vascular surgery is an important issue. The purpose of this study is to define whether perivascular application of rapamycin, imatinib mesylate or cysteamine...
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Role of Glutathione and Protective Effect of Cysteamine in the Ammonia Induced Gastric Mucosal injury -Related with the Mechanism of Helicobacter pylori Associated Gastric Diseases ??

Roe IH, Lee MI, Hwang HC, Kim HY, Chin YJ, Lim CY, Song IH, Kim JW, Yang MR, Cho CH, Lee JH

  • KMID: 2084878
  • Korean J Gastroenterol.
  • 1999 Jan;33(1):11-19.
BACKGROUND/AIMS: The mechanism of gastric mucosal injury by ammonia, one of the toxic products of Helicobacter pylori, is still unclear. We investigated the role and protective effect of glutathione in...
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Effect of Cysteamine on Human Peripheral Blood Mononuclear Cells-Chemically Injured Keratocytes Reaction

Lee YB, Hyon JY, Wee WR, Chung TY, Chung ES, Yi KY, Shin YJ

PURPOSE: To investigate the effect of cysteamine on mixed peripheral blood mononuclear cells (PBMCs)-chemically injured keratocytes reaction (mixed lymphocyte-keratocyte reaction; MLKR). METHODS: PBMC stimulation assay was performed after keratocytes were chemically...
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A Case of Cystinosis

Jung MH, Keun SO, Lee SJ, Lee BC

  • KMID: 1606831
  • J Korean Pediatr Soc.
  • 2003 Jun;46(6):615-619.
Cystinosis, an autosomal recessively inherited lysosomal storage disease, results from impaired transport of the amino acid cystine out of cellular lysosomes. The consequent accumulation and crystallization of cystine destroys tissues,...
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A role of endogenous somatostatin in exocrine secretion induced by intrapancreatic cholinergic activation

Park HS, Park IS, Kwon HY, Lee YL, Park HJ

  • KMID: 1562319
  • Korean J Physiol Pharmacol.
  • 1998 Apr;2(2):185-192.
A role of endogenous somatostatin in pancreatic exocrine secretion induced by intrapancreatic cholinergic activation was studied in the isolated rat pancreas perfused with modified Krebs-Henseleit solution. Intrapancreatic neurons were activated by electrical field...
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Modification of maturation condition improves oocyte maturation and in vitro development of somatic cell nuclear transfer pig embryos

Song K, Lee E

This study examined effects on the developmental competence of pig oocytes after somatic cell nuclear transfer (SCNT) or parthenogenetic activation (PA) of : 1) co-culturing of oocytes with follicular shell...
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Ghrelin - A Novel Appetite-stimulating Hormone Which Also Affects Gastrointestinal Functions

Suzuki H, Masaoka T, Hibi T

  • KMID: 782745
  • Korean J Gastroenterol.
  • 2006 Aug;48(2):82-88.
Ghrelin, a novel gastrointestinal peptide with 28 amino acids, is secreted from the A-like cells of the gastric fundus. This peptide hormone does not only promote the release of growth...
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Inhibition of LPS-induced cyclooxygenase 2 and nitric oxide production by transduced PEP-1-PTEN fusion protein in Raw 264.7 macrophage cells

Lee SH, Lee YP, Kim SY, Jeong MS, Lee MJ, Kang HW, Jeong HJ, Kim DW, Sohn EJ, Jang SH, Kim YH, Kwon HJ, Cho SW, Park J, Eum WS, Choi SY

Phosphatase and tensin homologue deleted on chromosome 10 (PTEN) is a tumor suppressor. Although it is well known to have various physiological roles in cancer, its inhibitory effect on inflammation...
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