- New COX-2 Inhibitors
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Kim D, Sung YK
- KMID: 2361428
- Korean J Med.
- 2016 Dec;91(3):250-256.
- doi: 10.3904/kjm.2016.91.3.350
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly used to treat pain and inflammation. There are two kinds of NSAID classified according to the selectivity of COX-2 inhibition: non-selective NSAIDs and cyclooxygenase... -
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- Anti-tumor mechanisms and regulation of survivin by selective cyclooxygenase-2 inhibitor
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Jang JW
- KMID: 1381460
- Korean J Hepatol.
- 2008 Sep;14(3):305-308.
- doi: 10.3350/kjhep.2008.14.3.305
No abstract available. -
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- The Effects of Lipoxygenase and Cyclooxygenase Inhibitors to Meningioma Cell Proliferation in vitro
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Park YS, Koo TH, Lee JH, Lee YB, Lee KC, Mok JH, Kim HS
- KMID: 1546426
- J Korean Neurosurg Soc.
- 2000 Jan;29(1):28-34.
No abstract available. -
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- Renal Effects of Prostaglandins and Cyclooxygenase-2 Inhibitors
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Kim GH
- KMID: 2052304
- Electrolyte Blood Press.
- 2008 Jun;6(1):35-41.
- doi: 10.5049/EBP.2008.6.1.35
Prostaglandins (PGs) with best-defined renal functions are PGE2 and prostacyclin (PGI2). These vasodilatory PGs increase renal blood flow and glomerular filtration rate under conditions associated with decreased actual or effective... -
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- Melittin-induced Nociceptive Responses are Alleviated by Cyclooxygenase-1 Inhibitor
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Kim J, Shin HK, Lee KH
- KMID: 1512941
- Korean J Physiol Pharmacol.
- 2006 Feb;10(1):45-50.
Melittin-induced pain model has been known to be very useful for the study of pain mechanism. Melittin-induced nociceptive responses are reported to be modulated by the changes in the activity... -
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- Study on the action by PAF on IL-1 modulation in alveolar macrophages: Involvement of endogenous arachidonate metabolites and intracellular Ca++ mobilization
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Lee J, Kim WK, Hah JS
- KMID: 1562327
- Korean J Physiol Pharmacol.
- 1998 Apr;2(2):241-249.
Platelet-activating factor (PAF) enhanced interleukin-1 (IL-1) activity by the interaction with a specific receptor in rat alveolar macrophages. In this study, we investigated the role of endogenous arachidonate metabolites and intracellular calcium mobilization... -
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- Individualized ibuprofen treatment using serial B-type natriuretic peptide measurement for symptomatic patent ductus arteriosus in very preterm infants
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Shin J, Lee EH, Lee JH, Choi BM, Hong YS
- KMID: 2383996
- Korean J Pediatr.
- 2017 Jun;60(6):175-180.
- doi: 10.3345/kjp.2017.60.6.175
PURPOSE: Plasma level of B-type natriuretic peptide (BNP), an emerging, sensitive, and specific biomarker of hemodynamically significant patent ductus arteriosus (PDA), rapidly decreases in infants receiving cyclooxygenase inhibitors for ductal... -
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- The Effects of Selective Cyclooxygenase-2 Inhibition in Puromycin Aminonucleoside Nephropathy Rats
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Lee DW, Son JM, Kim JH, Jeong YS, Lee SB, Kwak IS
- KMID: 2307255
- Korean J Nephrol.
- 2004 Sep;23(5):714-720.
BACKGROUND: It is known that non-steroidal antiinflammatory drugs (NSAIDs) reduce the amount of proteinuria in nephrotic syndrome. It is based on the facts that the NSAIDs block the production of... -
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- Effect of Prostaglandin F2alpha on the Production of Nitric Oxide in Cultured Ciliary Muscle Cells
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Kim JW, Kim YY, Kim KH
- KMID: 2207591
- J Korean Ophthalmol Soc.
- 2005 Jan;46(1):150-155.
PURPOSE: To investigate whether prostaglandin F2alpha (PGF2alpha) affects on the production of nitric oxide (NO) in cultured ciliary muscle (CM) cells. METHODS: Following primary culture of CM cells from porcine... -
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- Effect of Intrathecal COX Inhibitors on Inflammatory Pain and c-Fos Expression in Central Nervous System Induced by Formalin Injection in Rat
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Seo YS, Lee IO
- KMID: 2236648
- Korean J Anesthesiol.
- 2007 Jan;52(1):81-90.
- doi: 10.4097/kjae.2007.52.1.81
BACKGROUND: Prostaglandins (PGs) play important roles in the transmission of nociceptive information in the spinal cord. PGs are produced by cyclooxygenase (COX). Two forms of COX have been identified: COX-1... -
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- Selective cyclooxygenase inhibitors increase paclitaxel sensitivity in taxane-resistant ovarian cancer by suppressing P-glycoprotein expression
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Lee JP, Hahn HS, Hwang SJ, Choi JY, Park JS, Lee IH, Kim TJ
- KMID: 2288535
- J Gynecol Oncol.
- 2013 Jul;24(3):273-279.
- doi: 10.3802/jgo.2013.24.3.273
OBJECTIVE: The purpose of this study was to investigate whether selective cyclooxygenase (COX) inhibitors promote paclitaxel-induced apoptosis in taxane-resistant ovarian cancer cells by suppressing MDR1/P-glycoprotein (P-gp) expression. METHODS: Taxane-resistant ovarian cancer... -
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- The Effect of a Topical Selective Cyclooxygenase-2 Inhibitor on Skin-Wound Scarring of the Rabbit Ear
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Kim DY, Park JH, Chun BK, Han YS
- KMID: 2322433
- J Korean Soc Plast Reconstr Surg.
- 2011 Jul;38(4):351-358.
PURPOSE: The inflammatory phase is considered an integral part of adult wound healing, but fetal wound healing studies have shown scarless healing results in the absence of the inflammation process.... -
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- Recent Advance in Management of Patent Ductus Arteriosus in Extremely Low Birth Weight Infants
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Choi BM
- KMID: 2053718
- Hanyang Med Rev.
- 2009 Nov;29(4):315-326.
- doi: 10.7599/hmr.2009.29.4.315
Management of patent ductus arteriosus (PDA) in preterm infants has always been a challenge to the neonatologist and continues to be a controversial topic. There is no evidence that medical... -
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- Effects of Cyclooxygenase Inhibitors on Vascular Reactivity and Alterations of Cyclooxygenase Expression
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Lee KY, Park JW, Eum EA, Kang YJ, Lee KY, Choi HC
- KMID: 2320163
- Yeungnam Univ J Med.
- 2006 Jun;23(1):36-44.
BACKGROUND: There is controversy regarding whether COX-2 specific inhibitors are associated with elevation of blood pressure. We compared the effects of aspirin, indomethacin, and celecoxib for vascular reactivity induced by... -
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- The Effect of Selective Cyclooxygenase-2 Inhibitor on the Expression of Hypoxia-Inducible Factor-1alpha in Nasal Polyps
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Park SK, Jung CK, Han TH, Choi JB, Jang WH, Yang YI
- KMID: 1597338
- Korean J Otolaryngol-Head Neck Surg.
- 2005 May;48(5):601-605.
BACKGROUND AND OBJECTIVES: Nonsteroidal anti-inflammatory drugs (NSAIDs) are the most commonly used drugs in the world. NSAIDs are known to be potent inhibitors of the cyclooxygenase (COX) enzymes, a family... -
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- Cyclooxygenase Inhibitors, Aspirin and Ibuprofen, Inhibit MHC-restricted Antigen Presentation in Dendritic Cells
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Kim HJ, Lee YH, Im SA, Kim K, Lee CK
- KMID: 2150665
- Immune Netw.
- 2010 Jun;10(3):92-98.
- doi: 10.4110/in.2010.10.3.92
BACKGROUND: Nonsteroidal anti-inflammatory drugs (NSAIDs) are widely used to relieve pain, reduce fever and inhibit inflammation. NSAIDs function mainly through inhibition of cyclooxygenase (COX). Growing evidence suggests that NSAIDs also... -
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- Effects of Cyclooxygenase Inhibitors on Neuropathic Pain following Spinal Nerve Ligation in Rats
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Kang WS, Park JS, Kim JW, Yoon SM, Park JY
- KMID: 1894346
- Korean J Anesthesiol.
- 2005 Dec;49(6):S41-S46.
- doi: 10.4097/kjae.2005.49.6.S41
BACKGROUND: The facilitatory effect of spinal prostaglandins (PGs) on nociceptive transmission suggests that early PG synthesis after nerve injury could be important in the development of allodynia. METHODS: The aim of... -
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- Contact Urticaria - Relationship between Blocking Effect to Wheal Formation and Antiinflammatory Potencies of Some NSAID
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Yang JM, Yoo CH, Lee YS
- KMID: 2231377
- Korean J Dermatol.
- 1988 Feb;26(1):58-62.
This study was undertaken to investigate the response of non-immunologic contact urticaria(NICU) test before and after ingestion of cyclo-oxygenase inhibitors such as naproxene, ibuprofen and mefenamic acid. Forty patients who... -
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- Molecular Targets of Dietary Polyphenols with Anti-inflammatory Properties
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Yoon JH, Baek SJ
- KMID: 2158137
- Yonsei Med J.
- 2005 Oct;46(5):585-596.
- doi: 10.3349/ymj.2005.46.5.585
There is persuasive epidemiological and experimental evidence that dietary polyphenols have anti-inflammatory activity. Aspirin and other non-steroidal anti-inflammatory drugs (NSAIDs) have long been used to combat inflammation. Recently, cyclooxygenase (COX)... -
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- Role of Prostaglandins in Colon Cancer
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Myung SJ, Kim IH
- KMID: 1767526
- Korean J Gastroenterol.
- 2008 May;51(5):274-279.
Colon cancer is one of the major leading causes of cancer-related deaths in the Western countries. In Korea, the incidence of colon cancer is increasing due to changes in environment... -
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