- Effect of saccharin on inflammation in 3T3-L1 adipocytes and the related mechanism
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Kim HL, Ha AW, Kim WK
- KMID: 2471878
- Nutr Res Pract.
- 2020 Apr;14(2):109-116.
- doi: 10.4162/nrp.2020.14.2.109
BACKGROUND/OBJECTIVES: Excessive intake of simple sugars induces obesity and increases the risk of inflammation. Thus, interest in alternative sweeteners as a sugar substitute is increasing. The purpose of this study... -
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- Comparison of safety and analgesic efficacy of diclofenac sodium with etodolac after surgical extraction of third molars: a randomized, double-blind, double-dummy, parallel-group study
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Vaghela JH, Shah JH, Patel JH, Purohit BM
- KMID: 2471170
- J Dent Anesth Pain Med.
- 2020 Feb;20(1):19-27.
- doi: 10.17245/jdapm.2020.20.1.19
BACKGROUND: Surgical extraction of third molars is associated with postoperative pain and swelling at the extraction site. Pain is commonly managed using non-steroidal anti-inflammatory drugs (NSAIDs). Postoperative pain is usually... -
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- Curcumin Attenuates Acrolein-induced COX-2 Expression and Prostaglandin Production in Human Umbilical Vein Endothelial Cells
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Lee SE, Park HR, Jeon S, Han D, Park YS
- KMID: 2470810
- J Lipid Atheroscler.
- 2020 Jan;9(1):184-194.
- doi: 10.12997/jla.2020.9.1.184
OBJECTIVE: Inflammation is crucial to limiting vascular disease. Previously we reported that acrolein, a known toxin in tobacco smoke, might play an important role in the progression of atherosclerosis via... -
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- Inhibitory effect of carvacrol on lipopolysaccharide-induced memory impairment in rats
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Lee B, Yeom M, Shim I, Lee H, Hahm DH
- KMID: 2466567
- Korean J Physiol Pharmacol.
- 2020 Jan;24(1):27-37.
- doi: 10.4196/kjpp.2020.24.1.27
Neuroinflammation is an important process underlying a wide variety of neurodegenerative diseases. Carvacrol (CAR) is a phenolic monoterpene commonly used as a food additive due to its antibacterial properties, but... -
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- Effects of remifentanil preconditioning on factors related to uterine contraction in WISH cells
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Kim CH, Lee SH, Kim EJ, Ahn JH, Choi EJ, Yoon JU, Choi IS
- KMID: 2466649
- J Dent Anesth Pain Med.
- 2019 Dec;19(6):343-351.
- doi: 10.17245/jdapm.2019.19.6.343
BACKGROUND: Preterm labor and miscarriage may occur in stressful situations, such as a surgical operation or infection during pregnancy. Pharyngeal and buccal abscess and facial bone fractures are inevitable dental... -
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- Rhodanthpyrone A and B play an anti-inflammatory role by suppressing the nuclear factor-κB pathway in macrophages
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Kim KS, Han CY, Han YT, Bae EJ
- KMID: 2461042
- Korean J Physiol Pharmacol.
- 2019 Nov;23(6):493-499.
- doi: 10.4196/kjpp.2019.23.6.493
Macrophage-associated inflammation is crucial for the pathogenesis of diverse diseases including metabolic disorders. Rhodanthpyrone (Rho) is an active component of Gentiana rhodantha, which has been used in traditional Chinese medicine... -
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- Antinociceptive and anti-inflammatory effects of N-acetylcysteine and verapamil in Wistar rats
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Elberry AA, Sharkawi S, Wahba MR
- KMID: 2462835
- Korean J Pain.
- 2019 Oct;32(4):256-263.
- doi: 10.3344/kjp.2019.32.4.256
BACKGROUND: Antinociceptive anti-inflammatory drugs have many adverse effects. The goal of this investigation is to study the probable anti-inflammatory and analgesic effects of verapamil and N-acetylcysteine (NAC) in experimental rats. METHODS:... -
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- 15-Deoxy-Δ(12,14)-prostaglandin J₂ Upregulates the Expression of 15-Hydroxyprostaglandin Dehydrogenase by Inducing AP-1 Activation and Heme Oxygenase-1 Expression in Human Colon Cancer Cells
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Park JM, Na HK
- KMID: 2468800
- J Cancer Prev.
- 2019 Sep;24(3):183-191.
- doi: 10.15430/JCP.2019.24.3.183
BACKGROUND: Abnormal upregulation of prostaglandin Eâ‚‚ (PGEâ‚‚) is considered to be a key oncogenic event in the development and progression of inflammation-associated human colon cancer. It has been reported that... -
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- The Effect of Saccharin on the Gene Expression of NF-κB and Inflammatory Cytokines in LPS-Stimulated SW480 Colon Cancer Cells
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Choi H, Kim S, Kang H, Kim M, Kim W
- KMID: 2455070
- J Korean Diet Assoc.
- 2019 Aug;25(3):217-228.
- doi: 10.14373/JKDA.2019.25.3.217
There have been no published studies concerning the anti-inflammatory effects of corn silk on colon cancer cells. Thus, this study was conducted to investigate the effect of corn silk extract... -
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- Protective effect of Cordyceps militaris against hydrogen peroxide-induced oxidative stress in vitro
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He MT, Lee AY, Park CH, Cho EJ
- KMID: 2453105
- Nutr Res Pract.
- 2019 Aug;13(4):279-285.
- doi: 10.4162/nrp.2019.13.4.279
BACKGROUND/OBJECTIVES: Excessive production of reactive oxygen species (ROS) such as hydroxyl (·OH), nitric oxide (NO), and hydrogen peroxide (H2O2) is reported to induce oxidative stress. ROS generated by oxidative stress... -
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- 4′-O-β-D-Glucosyl-5-O-Methylvisamminol Attenuates Pro-Inflammatory Responses and Protects against Oxidative Damages
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Yoo OK, Keum YS
- KMID: 2455093
- Biomol Ther.
- 2019 Jul;27(4):381-385.
- doi: 10.4062/biomolther.2018.232
We attempted to examine anti-inflammatory and anti-oxidant effects of 4′-O-β-D-glucosyl-5-O-methylvisamminol (GOMV), the first epigenetic inhibitor of histone phosphorylation at Ser10. While GOMV did not affect the viability of murine macrophage... -
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- Baicalein Inhibits Dextran Sulfate Sodium-induced Mouse Colitis
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Zhong X, Surh YJ, Do SG, Shin E, Shim KS, Lee CK, Na HK
- KMID: 2454672
- J Cancer Prev.
- 2019 Jun;24(2):129-138.
- doi: 10.15430/JCP.2019.24.2.129
BACKGROUND: Baicalein is a bioactive flavone that is originally extracted from the root of Scutellaria baicalensis Georgi. This plant has long served as Chinese herbal medicine in the management of... -
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- Anti-inflammatory effect of aged black garlic on 12-O-tetradecanoylphorbol-13-acetate-induced dermatitis in mice
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You BR, Yoo JM, Baek SY, Kim MR
- KMID: 2453282
- Nutr Res Pract.
- 2019 Jun;13(3):189-195.
- doi: 10.4162/nrp.2019.13.3.189
BACKGROUND/OBJECTIVES: Although aged black garlic has various biological activities such as anti-allergy, anti-inflammation and neuroprotection, effect of aged black garlic on chemically contact dermatitis is unclarified. MATERIALS/METHODS: To evaluate anti-dermatitic activity... -
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- Propofol Suppresses LPS-Induced Inflammation in Amnion Cells via Inhibition of NF-κB Activation
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Yoon JY, Kim DW, Ahn JH, Choi EJ, Kim YH, Jeun M, Kim EJ
- KMID: 2449240
- Tissue Eng Regen Med.
- 2019 Jun;16(3):301-309.
- doi: 10.1007/s13770-019-00194-y
BACKGROUND: Preterm labor is a leading risk factor for neonatal death and long-term impairment and linked closely with inflammation. Non-obstetric surgery is occasionally needed during pregnancy and the anesthetic drugs... -
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- Anti-nociceptive and Anti-inflammatory Properties of Ilex latifolia and its Active Component, 3,5-Di-caffeoyl Quinic Acid Methyl Ester
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Kim JY, Lee HK, Seong YH
- KMID: 2443106
- Nat Prod Sci.
- 2019 Mar;25(1):64-71.
- doi: 10.20307/nps.2019.25.1.64
The present study was conducted to investigate anti-nociceptive and anti-inflammatory effects of the leaves of Ilex latifolia Thunb (I. latifolia) in in vivo and in vitro. Writhing responses induced by... -
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- Anti-inflammatory Activity of Standardized Fraction from Inula helenium L. via Suppression of NF-κB Pathway in RAW 264.7 Cells
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Chun J, Song K, Kim YS
- KMID: 2443098
- Nat Prod Sci.
- 2019 Mar;25(1):16-22.
- doi: 10.20307/nps.2019.25.1.16
Inula helenium L. is rich source of eudesmane-type sesquiterpene lactones, mainly alantolactone and isoalantolactone, which have the various pharmacological functions. In this study, we examined the inhibitory effects of nitric... -
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- Phenotypes of Severe Cutaneous Adverse Reactions Caused by Nonsteroidal Anti-inflammatory Drugs
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Lee SY, Nam YH, Koh YI, Kim SH, Kim S, Kang HR, Kim MH, Lee JG, Park JW, Park HK, La HO, Kim MY, Park SJ, Kwon YE, Jung JW, Kim SH, Kim CW, Yang MS, Kang MG, Lee JY, Kim JH, Kim SH, Hur GY, Jee YK, Jin HJ, Park CS, Jeong YY, Ye YM
- KMID: 2431853
- Allergy Asthma Immunol Res.
- 2019 Mar;11(2):212-221.
- doi: 10.4168/aair.2019.11.2.212
PURPOSE: Nonsteroidal anti-inflammatory drugs (NSAIDs) are common cause of severe cutaneous adverse reactions (SCARs). The present study aimed to investigate the characteristics of SCARs induced by NSAIDs in the Korean... -
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- Gene Expression in Cultured Keloid Fibroblasts
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Kim DH, Kim UK, Choi KH, Park K
- KMID: 2440723
- Korean J Dermatol.
- 2019 Feb;57(2):59-65.
BACKGROUND: Keloids are the result of an overgrowth of dense fibrous tissue. The mechanisms involved in keloid formation remain unknown. OBJECTIVE: To understand the mechanism of keloid formation, differences in gene... -
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- Amelioration of experimental autoimmune encephalomyelitis by Ishige okamurae
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Ahn M, Kim J, Yang W, Choi Y, Ekanayake , Ko H, Jee Y, Shin T
- KMID: 2430197
- Anat Cell Biol.
- 2018 Dec;51(4):292-298.
- doi: 10.5115/acb.2018.51.4.292
Experimental autoimmune encephalomyelitis (EAE) is a T-cell-mediated autoimmune central nervous system disease characterized by inflammation with oxidative stress. The aim of this study was to evaluate an anti-inflammatory effect of... -
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- From Gut to Brain: Alteration in Inflammation Markers in the Brain of Dextran Sodium Sulfate-induced Colitis Model Mice
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Do J, Woo J
- KMID: 2428972
- Clin Psychopharmacol Neurosci.
- 2018 Nov;16(4):422-433.
- doi: 10.9758/cpn.2018.16.4.422
OBJECTIVE: Neuropsychiatric manifestations like depression and cognitive dysfunction commonly occur in inflammatory bowel disease (IBD). In the context of the brain-gut axis model, colitis can lead to alteration of brain... -
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