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Oxidative Stress Modulates the Expression Pattern of Peroxiredoxin-6 in Peripheral Blood Mononuclear Cells of Asthmatic Patients and Bronchial Epithelial Cells

Shim HJ, Park SY, Kwon HS, Song WJ, Kim TB, Moon KA, Choi JP, Kim SJ, Cho YS

PURPOSE: Reduction-oxidation reaction homeostasis is vital for regulating inflammatory conditions and its dysregulation may affect the pathogenesis of chronic airway inflammatory diseases such as asthma. Peroxiredoxin-6, an important intracellular anti-oxidant...
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Fluoxetine Induces Apoptotic and Oxidative Neuronal Death Associated with The Influx of Copper Ions in Cultured Neuronal Cells

Hwang S, Kim JK

We examined the effect of fluoxetine, a selective serotonin reuptake inhibitor antidepressant, on neuronal viability in mouse cortical near-pure neuronal cultures. Addition of fluoxetine to the media for 24 hours...
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Bisifusarium Delphinoides, an Emerging Opportunistic Pathogen in a Burn Patient with Diabetes Mellitus

Park JH, Oh J, Song JS, Kim J, Sung GH

An 82-year-old man with diabetes was admitted to the emergency department with a third-degree burn on his left leg. The deep swab specimen from his left leg was cultured on...
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Chicken RNA-binding protein T-cell internal antigen-1 contributes to stress granule formation in chicken cells and tissues

Sun Y, Zhang P, Zheng H, Dong L, Tan L, Song C, Qiu X, Liao Y, Meng C, Yu S, Ding C

T-cell internal antigen-1 (TIA-1) has roles in regulating alternative pre-mRNA splicing, mRNA translation, and stress granule (SG) formation in human cells. As an evolutionarily conserved response to environmental stress, SGs...
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NADPH Oxidase Mediates β-Amyloid Peptide-Induced Neuronal Death in Mouse Cortical Cultures

Chay KO, Nam Koong , Hwang S, Kim JK, Bae CS

β-Amyloid peptide (Aβ) is the main component of senile plaques in patients with Alzheimer's disease, and is known to be a main pathogenic factor of the disease. Recent evidence indicates...
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Clinical Study of Onychomycosis Observed in Children (2005~2014)

Kim NH, Yun SJ, Lee JB, Kim SJ, Lee SC, Won YH

  • KMID: 2368890
  • Korean J Dermatol.
  • 2016 Dec;54(10):781-787.
BACKGROUND: Pediatric onychomycosis has been previously investigated; however, the specific causative agents of onychomycosis in Korean children have not been reported. OBJECTIVE: This study aimed to determine the most common causative...
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Cytotoxic Effects of Gallic Acid and its Derivatives Against HIV-I-infected Microglia

Jeong JJ, Lee YS, Kim DH

In the previous study, we found that flavonoids and ginsenosides exhibited high eliminate rates of human immunodeficiency virus type 1 (HIV-1) D3-transfected macrophages. Based on these findings, here we synthesized...
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Brief low [Mg2+]o-induced Ca2+ spikes inhibit subsequent prolonged exposure-induced excitotoxicity in cultured rat hippocampal neurons

Kim HJ, Yang JS, Yoon SH

Reducing [Mg2+]o to 0.1 mM can evoke repetitive [Ca2+]i spikes and seizure activity, which induces neuronal cell death in a process called excitotoxicity. We examined the issue of whether cultured...
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Protective Effects of Inducible HO-1 on Oxygen Toxicity in Rat Brain Endothelial Microvessel Cells

Yoo SJ, Nakra NK, Ronnett GV, Moon C

BACKGROUND: Reperfusion in ischemia is believed to generate cytotoxic oxidative stress, which mediates reperfusion injury. These stress conditions can initiate lipid peroxidation and damage to proteins, as well as promote...
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A Clinical and Mycological Study of Onychomycosis in the Elderly Over 10 Years (2001-2010)

Yoo JY, Suh MK, Ha GY, Kim H

  • KMID: 1773700
  • Korean J Med Mycol.
  • 2014 Dec;19(4):83-92.
BACKGROUND: As the life expectancy has risen globally because of the advance of medicine, onychomycosis in the elderly has been increasing with higher concerns over nails. Onychomycosis has been studied...
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Onychomycosis in Children: An Experience of 59 Cases

Kim DM, Suh MK, Ha GY

BACKGROUND: Although tinea unguium in children has been studied in the past, no specific etiological agents of onychomycosis in children has been reported in Korea. OBJECTIVE: The purpose of this study...
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Quantitative in Vivo Detection of Brain Cell Death after Hypoxia Ischemia Using the Lipid Peak at 1.3 ppm of Proton Magnetic Resonance Spectroscopy in Neonatal Rats

Ahn SY, Yoo HS, Lee JH, Sung DK, Jung YJ, Sung SI, Lim KH, Chang YS, Lee JH, Kim KS, Park WS

This study was performed to determine the accuracy of proton magnetic spectroscopy (1H-MRS) lipid peak as a noninvasive tool for quantitative in vivo detection of brain cell death. Seven day-old...
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A Clinico-mycological Study of Onychomycosis with Dermatophytoma

Lee MH, Suh MK, Ha GY

  • KMID: 1432012
  • Korean J Med Mycol.
  • 2013 Jun;18(2):21-29.
BACKGROUND: Although there have been many studies about onychomycosis, the study about onychomycosis with dermatophytoma has not been reported yet in Korea. OBJECTIVE: The purpose of this study was to investigate...
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Onychomycosis Caused by Chaetomium globosum

Kim DM, Lee MH, Suh MK, Ha GY, Kim H, Choi JS

Onychomycosis is usually caused by dermatophytes, but some nondermatophytic molds and yeasts are also associated with invasion of nails. The genus Chaetomium is a dematiaceous nondermatophytic mold found in soil...
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Contamination of Slippers in Operating Room by Dermatophytes and Effect of Antifungal Agent (Terbinafine) Disinfection

Chung KH, Park JS, Chung H, Jun JB, Bang YJ

  • KMID: 2243033
  • Korean J Med Mycol.
  • 2012 Sep;17(3):168-175.
BACKGROUND: It is known that floor, clothes, shoes and slippers of common uses are the sources of infection by dermatophytes. However there hasn't been any report about the culture of...
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Molecular Identification of Schizophyllum commune as a Cause of Allergic Fungal Sinusitis

Won EJ, Shin JH, Lim SC, Shin MG, Suh SP, Ryang DW

Schizophyllum commune, a basidiomycetous fungus, rarely causes disease in humans. We report a rare case of allergic fungal sinusitis caused by S. commune in a 14-yr-old girl. The patient presented...
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Onychomycosis Due to Nondermatophytic Molds

Hwang SM, Suh MK, Ha GY

  • KMID: 2434683
  • Ann Dermatol.
  • 2012 May;24(2):175-180.
BACKGROUND: Although there have been many studies about onychomycosis due to nondermatophytic molds (NDM), few studies about etiologic agents including NDM in onychomycosis have been reported in Korea. Objective: This...
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Dexamethasone Induces FcgammaRIIb Expression in RBL-2H3 Cells

Silwal P, Lee MN, Lee CJ, Hong JH, Namgung U, Lee ZW, Kim J, Lim K, Kweon GR, Park JI, Park SK

Mast cells are involved in allergic responses, protection against pathogens and autoimmune diseases. Dexamethasone (Dex) and other glucocorticoids suppress FcepsilonRI-mediated release of inflammatory mediators from mast cells. The inhibition mechanisms...
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Fingernail Onychomycosis Due to Aspergillus niger

Kim DM, Suh MK, Ha GY, Sohng SH

Onychomycosis is usually caused by dermatophytes, but some species of nondermatophytic molds and yeasts are also associated with nail invasion. Aspergillus niger is a nondermatophytic mold which exists as an...
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Investigation of Murine Norovirus Replication in RAW264.7 Cells by Strand-specific RT-PCR

Ji GY, Jang SY, Paik SY, Ko GP, Jeong WH, Lee CH

Murine norovirus (MNV) is a non-enveloped virus with a positive-sense RNA genome and causes lethal infection in mice. MNV has been used as a model virus for human norovirus (NV)...
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