- Cultured Corneal Keratocyte: Scanning and Transmission Electron Microscopic Findings
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Ko MK, Kim DC
- KMID: 2336396
- J Korean Ophthalmol Soc.
- 1987 Apr;28(2):279-284.
The cultured cells were derived from rabbit corneal stroma by explant technique following microdissection and serial passage. The ultrastructural features of fourteenth-passage keratocytes were examined with both scanning and transmission... -
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- Gene Microarray Related with Apoptosis in Diabetic OLETF Keratocytes
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Lee JE, Kim HS, Lee JS
- KMID: 2337383
- J Korean Ophthalmol Soc.
- 2006 May;47(5):818-827.
PURPOSE: This study was to identified differentiated genes concerned with apoptosis that are up-regulated or down-regulated in OLETF corneal keratocytes stimulated with interleukin-1alpha. METHODS: Otsuka Long Evans Tokushima Fatty (OLETF) corneal... -
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- Lipopolysaccharide-induced Production of Interleukin-8 by Cultured Human Keratocyte
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Lee SJ, Lee DJ, Hahn YH
- KMID: 2127732
- J Korean Ophthalmol Soc.
- 2000 Oct;41(10):2051-2059.
The authors performed an experiment to determine if human corneal keratocytes release IL-8 after stimulation with lipopolysaccharide (LPS). Human corneal keratocytes were isolated from human corneal buttoms and grown independently... -
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- Gene Transfer into Corneal Keratocytes using a Hybrid EBV/retroviral Vector
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Cho BJ, Park I, Kim MK, Wee WR, Lee JH
- KMID: 2109299
- J Korean Ophthalmol Soc.
- 2002 Mar;43(3):571-577.
PURPOSE: We tried to determine the feasibility and efficiency of foreign gene transfer into corneal keratocytes using a hybrid EBV/retroviral vector as an investigative trial for gene therapy in corneal... -
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- The Effect of Candida albicans and Dexamethasone on the Secretion of Tumor Necrosis Factor-alpha from Cultured Human Keratocytes
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Bay SW, Jang YS, Hahn YH
- KMID: 2206216
- J Korean Ophthalmol Soc.
- 2002 Oct;43(10):2010-2016.
PURPOSE: To measure the secretion of TNF-alpha from cultured human keratocytes after inoculation of Candida albicans, and to evaluate the change of secretion of TNF-alpha following application of dexamethasone. METHODS:... -
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- Effect of Amoebicidal Agents on the Human Corneal Keratocytes in Vitro
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Lee JE, Lee JS, Choi HY, Yoo HS
- KMID: 2210753
- J Korean Ophthalmol Soc.
- 2007 Jan;48(1):125-134.
PURPOSE: To evaluate the effect of polyhexamethylene biguanide (PHMB) and chlorhexidine on Acanthamoeba cysts and cultured human keratocytes. METHODS: Each well of two-fold diluted PHMB and chlorhexidine were treated on the... -
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- Effect of Tranilast on the Proliferation of Human Corneal Keratocytes in Vitro
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Lee JE, Han HJ, Lee JS, Oum BS
- KMID: 2207723
- J Korean Ophthalmol Soc.
- 2005 Mar;46(3):510-520.
PURPOSE: To evaluate the inhibitory effect of tranilast on proliferation of cultured human keratocytes, and to investigate the apoptotic response and the cellular morphologic changes associated with tranilast in vitro.... -
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- Apoptosis of Keratocytes Induced by Mitomycin C
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Choi J, Kim TI, Tchah H
- KMID: 1902562
- J Korean Ophthalmol Soc.
- 2004 Mar;45(3):490-499.
PURPOSE: The purpose of this study was to evaluate the effect of mitomycin C on rabbit keratocytes for their potential to modulate corneal stromal wound healing. We also investigated the... -
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- Effect of Mitomycin C, Dexamethasone, and Cyclosporine A 0.05% on the Proliferation of Human Corneal Keratocytes
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Shin JH, Kim SJ, Lee JE, Lee JS
- KMID: 2215005
- J Korean Ophthalmol Soc.
- 2011 Oct;52(10):1215-1221.
- doi: 10.3341/jkos.2011.52.10.1215
PURPOSE: To investigate the biologic effect of mitomycin C, dexamethasone and cyclosporine A 0.05% on cultured human keratocytes in vitro. METHODS: Human corneal keratocytes were exposed to a concentration of mitomycin... -
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- Ceramide-Induced Apoptosis in Cultured Keratocyte
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Park HR, Kim TI, Tchah HW
- KMID: 2125617
- J Korean Ophthalmol Soc.
- 2003 Apr;44(4):945-954.
PURPOSE: We investigated the effect of ceramide on keratocyte apoptosis and pathway of ceramide-induced keratocyte apoptosis. METHODS: Cultured Newzealand White Rabbit keratocytes were exposed to various concentrations of ceramide type... -
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- Effect of Dexamethasone and Diclofenac on the Proliferation of Human Corneal Keratocytes
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Lee JE, Lee SU, Kim JH, Lee JS
- KMID: 2207589
- J Korean Ophthalmol Soc.
- 2005 Jan;46(1):133-143.
PURPOSE: To evaluate the inhibitory effect of dexamethasone and diclofenac on the proliferation of cultured human keratocytes, and to investigate the apoptotic response and the cellular morphologic changes associated with... -
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- Effective Keratocyte Culture Using Amniotic Membrane Matrix and Differentiation of Mesenchymal Stem Cells
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Park SH, Chun YS, Kim JC
- KMID: 2337906
- J Korean Ophthalmol Soc.
- 2010 Dec;51(12):1652-1658.
PURPOSE: To investigate the characteristics of cultured rabbit corneal keratocytes in vitro and evaluate the possibility of differentiation of mesenchymal stem cells to keratocytes using the keratocyte conditioned medium (KCM). METHODS:... -
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- Effects of Gel Type Artificial Tears on Human Corneal Keratocytes and Conjunctival Epithelial Cells
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Lee JS, Kim EH, Kim SJ, Lee JE, Kim NM
- KMID: 2337905
- J Korean Ophthalmol Soc.
- 2010 Dec;51(12):1643-1651.
PURPOSE: To evaluate the biological effects and cytotoxicity of gel-type artificial tears on human corneal keratocytes and conjunctival cells in vitro. METHODS: Human corneal keratocytes and conjunctival epithelial cells were exposed... -
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- A Case of Korean Patient with Macular Corneal Dystrophy Associated with Novel Mutation in the CHST6 Gene
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Lee YK, Chang DJ, Chung SK
- KMID: 1792082
- Korean J Ophthalmol.
- 2013 Dec;27(6):454-458.
- doi: 10.3341/kjo.2013.27.6.454
To report a novel mutation within the CHST6 gene, as well as describe light and electron microscopic features of a case of macular corneal dystrophy. A 59-year old woman with... -
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- Effect of Anti-inflammatory Mediator on the Proliferation of Human Corneal Keratocyte
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Lee JS, Bae H, Koo GH, Oum BS
- KMID: 2206310
- J Korean Ophthalmol Soc.
- 2002 Dec;43(12):2534-2542.
PURPOSE: The purpose of this study was to evaluate the effect of anti-inflammatory mediators like dexamethasone, nordihyroguaratic acid (NDGA), and diclofenac sodium on proliferation of human corneal keratocytes, and to... -
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- Inhibitory Effect of Mitomycin C (MMC) on the Proliferation of Human Corneal Keratocyte
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Lee JE, Lee JS
- KMID: 2206308
- J Korean Ophthalmol Soc.
- 2002 Dec;43(12):2519-2526.
PURPOSE: To evaluate the anti-proliferative effect of mitomycin C (MMC) on human corneal keratocyte, and to investigate the cellular morphology of keratocyte according to the concentration and exposure time in... -
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- Effects of Damaged Human Corneal Epithelial Cells on Differentiation of Human Mesenchymal Stem Cell
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Shin MS, Hong HS, Son YS, Kim JC
- KMID: 2126715
- J Korean Ophthalmol Soc.
- 2007 Mar;48(3):423-430.
PURPOSE: To identify the effects of microenvironmental changes caused by human corneal epithelial damages to characteristics or differentiation of human mesenchymal stem cells (hMSCs). METHODS: Artificial corneal damage was induced onto... -
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- Nitric Oxide-Mediated Neurotoxicity after Excimer Laser Photorefractive Keratectomy
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Joo MJ, Lee KJ, Shin KH, Kim JC
- KMID: 2205473
- J Korean Ophthalmol Soc.
- 1999 Mar;40(3):688-698.
The aim of this study was to evaluate neurotoxicity of Nitric oxide(NO) on cornea after excimer laser photorefractive keratectomy(PRK). PRK was performed on rabbit eyes. According to the time table,... -
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- Effects of Intrastromal Air Injection Compared to Hydro-injection on Keratocyte Apoptosis
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Lee MJ, Lee HJ, Wee WR, Lee JH, Kim MK
- KMID: 2210855
- J Korean Ophthalmol Soc.
- 2007 Apr;48(4):555-562.
PURPOSE: To evaluate the effects of intrastromal air injection and intrastromal balanced salt solution (BSS) injection on corneal keratocyte apoptosis. METHODS: Twelve right eyes of New Zealand White rabbits were divided... -
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