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Bilateral Hearing Loss in Wernicke Encephalopathy

Bae H, Park JY, Cho HS, Lim SH, Ha SW

Wernicke encephalopathy is a syndrome caused by thiamine deficiency whose three typical symptoms are ophthalomoplegia, ataxia, and confusion. There are also rare reports of bilateral hearing loss, which can be...
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Effect of Ginkgo Biloba Extract on N-Methyl-D-Aspartic Acid Receptor Subunit 2B Expression in a Salicylate-Induced Ototoxicity Model

Lee SY, Han SY, Shim YJ, Han JJ, Cho D, Kim JE, Kim YH

OBJECTIVES.: Sodium salicylate (SS) is well known for its ototoxic properties that induce functional and morphological changes in the cochlea and brain. Ginkgo biloba extract (GBE) has been widely used...
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Duplicated Internal Auditory Canal: High-Resolution CT and MRI Findings

Wang L, Zhang L, Li X, Guo X

OBJECTIVE: To summarize the high-resolution computed tomography (HRCT) and magnetic resonance imaging (HRMRI) features of duplicated internal auditory canals (DIACs). MATERIALS AND METHODS: Ear HRCT data of 64813 patients with sensorineural...
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Effects of Dexmedetomidine Infusion During Sevoflurane Anesthesia on Otoacoustic Emissions

Åžahin MÄ, Vural A, Akın A, Ketenci Ä, Ãœnlü Y

BACKGROUND AND OBJECTIVES: Knowing the ototoxic potential of the agents used in medical treatments is important for the protection of hearing. Although we have knowledge regarding some effects of dexmedetomidine,...
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Auditory Deficits in Patients With Mild and Moderate Obstructive Sleep Apnea Syndrome: A Speech Syllable Evoked Auditory Brainstem Response Study

Fu Q, Wang T, Liang Y, Lin Y, Zhao X, Wan J, Fan S

OBJECTIVES: The energy consumption process of cochlea and neural signal transduction along the auditory pathway are highly dependent on blood oxygen supply. At present, it is under debate on whether...
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Losartan Prevents Maladaptive Auditory-Somatosensory Plasticity After Hearing Loss via Transforming Growth Factor-β Signaling Suppression

Mun SK, Han KH, Baek JT, Ahn SW, Cho HS, Chang MY

OBJECTIVES: Hearing loss disrupts the balance of auditory-somatosensory inputs in the cochlear nucleus (CN) of the brainstem, which has been suggested to be a mechanism of tinnitus. This disruption results...
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Cochlear Damage Caused by the Striking Noise of Titanium Head Golf Driver

Park YH, Chung J, Lee MY, Lee DY, Kim YH

OBJECTIVES.: To investigate how mouse cochleae are affected by the striking noise of titanium head golf driver. METHODS.: Thirty-two BALB/c mice (20–22 g) with normal hearing were used. The impact acoustic...
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A Case of Bilateral Semicircular Canal Dysplasia with Normal Cochlear Found in Bilateral Vestibulopathy

Lee S, Choi SW

A 25-year-old woman presented with atypical dizziness with oscillopsia. The neuro-otological evaluations showed bilateral vestibulopathy with mild sensorineural hearing loss. Computed tomography and magnetic resonance imaging demonstrated bilateral isolated lateral...
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The Value of Posterior Semicircular Canal Function in Predicting Hearing Recovery of Sudden Sensorineural Hearing Loss

Shin JW, Kim SW, Kim YW, Jang W, Kim BH, Lim YS, Park SW, Cho CG, Park JH

OBJECTIVES: Postulated etiologies for idiopathic sudden sensorineural hearing loss (SSNHL) include viral cochleitis, microvascular events. If SSNHL is caused by vascular compromise of common cochlear artery that supplies cochlea and...
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Comparison of Temporal Bone Parameters before Cochlear Implantation in Patients with and without Facial Nerve Stimulation

Kasetty VM, Zimmerman , King S, Seyyedi M

BACKGROUND AND OBJECTIVES: Facial nerve stimulation (FNS) is a complication of cochlear implantation (CI). This study compared the thickness and density of the bone separating the upper basal turn of...
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Limitation of High Pitch Sound Perception in Nontumor Patients with Auditory Brainstem Implantation

Choi HS, Choi JY, Moon IS, Bae MR, Kim BG, Kim M, Chang JW, Jeong J

BACKGROUND AND OBJECTIVES: Auditory brainstem implantation (ABI) is another option for hearing rehabilitation in non-neurofibromatosis type 2 patients who cannot undergo cochlear implantation (CI). However, the average performance of ABI...
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The Protective Effect of Egb 761 Against 3-Nitropropionic Acid-Induced Hearing Loss: The Role of Sirtuin 1

Chang MY, Rhee J, Kim SH, Kim YH

OBJECTIVES: Local administration of 3-nitropropionic acid (3-NP) to the inner ear induces sensorineural hearing loss. Several studies have shown the otoprotective effects of ginkgo biloba extract EGb 761. Moreover, EGb...
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The Presence of Neural Stem Cells and Changes in Stem Cell-Like Activity With Age in Mouse Spiral Ganglion Cells In Vivo and In Vitro

Moon BS, Ammothumkandy A, Zhang N, Peng L, Ibrayeva A, Bay M, Pratap A, Park HJ, Bonaguidi , Lu W

OBJECTIVES: Spiral ganglion neurons (SGNs) include potential endogenous progenitor populations for the regeneration of the peripheral auditory system. However, whether these populations are present in adult mice is largely unknown....
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A Case of Middle Ear Implantation Using the Vibrant Soundbridge in a Patient with Bilateral Mixed Hearing Loss

Shin YG, Gu JW, Kang JW, Song MH

It is challenging to achieve sufficient hearing gain in patients with mixed hearing loss. In chronic middle ear diseases, conventional passive reconstructive surgeries often result in suboptimal hearing gain and...
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A Case of Scala Vestibuli Cochlear Implantation in Tympanogenic Labyrinthitis Ossificans

Lee YS, Heo JH, Park YH, Choi JW

Labyrinthitis ossificans (LO) is a pathologic formation of fibrosis and new bone within the lumen of the otic capsule. The LO is a challenging issue in cochlear implantation since obliteration...
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Gene Therapy for Hearing Protection

Lee MY

Sensorineural hearing loss (SNHL) does not recover and only few exceptions exist. It is mostly due to the reason that hair cells in the cochlea cannot regenerate once damaged. Therefore,...
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Functional Significance of Medial Olivocochlear System Morphology in the Mouse Cochlea

Park SY, Park JM, Back SA, Yeo SW, Park SN

OBJECTIVES: Baso-apical gradients exist in various cochlear structures including medial olivocochlear (MOC) efferent system. This study investigated the cochlear regional differentials in the function and morphology of the MOC system,...
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Response to Letter by Dr. Cristina Brandolini

Kim HA, Lee H

No abstract available.
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Over-expression of myosin7A in cochlear hair cells of circling mice

Kim YY, Nam H, Jung H, Kim B, Suh JG

Circling mouse (C57BL/6J-cir/cir) deleted the transmembrane inner ear (Tmie) gene is an animal model for human non-syndromic recessive deafness, DFNB6. In circling mouse, hair cells in the cochlea have degenerated...
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Ménière's Disease and Electrophysiology

Kim SH

Inner ear is composed of cochlea, vestibule, and endolymphatic sac which are enclosed by thin layer of epithelial cells. The enclosed space is filled with fluid named as endolymph where...
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