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Partial Characterization of Two Cathepsin D Family Aspartic Peptidases of Clonorchis sinensis

Kang JM, Yoo WG, Lê HG, Thái TL, Hong SJ, Sohn WM, Na BK

Cathepsin D (CatD, EC 3.4.23.5) is a member belonging to the subfamily of aspartic endopeptidases, which are classified into the MEROPS clan AA, family A1. Helminth parasites express a large...
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Cytokine Production in Cholangiocarcinoma Cells in Response to Clonorchis sinensis Excretory-Secretory Products and Their Putative Protein Components

Pak JH, Lee JY, Jeon BY, Dai F, Yoo WG, Hong SJ

Clonorchis sinensis is a carcinogenic human liver fluke that promotes hepatic inflammatory environments via direct contact or through their excretory-secretory products (ESPs), subsequently leading to cholangitis, periductal fibrosis, liver cirrhosis,...
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Cytochrome C Oxidase Subunit 1, Internal Transcribed Spacer 1, Nicotinamide Adenine Dinucleotide Hydrogen Dehydrogenase Subunits 2 and 5 of Clonorchis sinensis Ancient DNA Retrieved from Joseon Dynasty Mummy Specimens

Hong JH, Oh CS, Chai JY, Seo M, Shin DH

We analyzed Clonorchis sinensis ancient DNA (aDNA) acquired from the specimens of the Joseon mummies. The target regions were cytochrome C oxidase subunit 1 (CO1), internal transcribed spacer 1 (ITS1),...
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Clonorchis sinensis Infection Presenting as Acute Cholangitis and Acute Cholecystitis

Yang YM, Choi H, Ryu DH, Woo CG, Han JH, Park SM

A 59-year-old woman presented with abdominal pain. Abdominal computerized tomography was suggestive of biliary stones. During endoscopic retrograde cholangiopancreatography, adult worms resembling Clonorchis sinensis (C. sinensis) were drained. Eggs were...
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Infection Status with Clonorchis sinensis Metacercariae in Fish from Yangcheon (Stream) in Sancheong-gun, Gyeongsangnam-do, Korea

Sohn WM, Na BK, Cho SH, Ju JW

The infection status with Clonorchis sinensis metacercariae (CsMc) was examined in freshwater fishes from Yangcheon (a branch of Gyeongho-gang), which is located in Sancheong-gun, Gyeongsangnam-do, the Republic of Korea. Total...
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Infection Status with Clonorchis sinensis Metacercariae in Fish from Tamjin-gang (River) in Jeollanam-do, Republic of Korea

Yoon KB, Lim HC, Jeon DY, Park S, Cho SH, Ju JW, Shin SS, Na BK, Sohn WM

The present study was performed to investigate the infection status with Clonorchis sinensis metacercariae (CsMc) in fishes from 2 sites, the middle and lower reaches, of Tamjin-gang (River) in Jeollanam-do,...
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Prevalence and Intensity of Clonorchis sinensis Metacercariae in Freshwater Fish from Wicheon Stream in Gunwi-gun, Gyeongsangbuk-do, Korea

Sohn WM, Na BK, Cho SH, Ju JW, Son DC

The infection status of Clonorchis sinensis metacercariae (CsMc) was examined in freshwater fish from a highly prevalent site, Wicheon (a branch of Nakdong-gang), which is located in Gunwi-gun, Gyeongsangbuk-do, the...
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Prevalence of Clonorchis sinensis Metacercariae in Fish from Water Systems of Seomjin-gang (River)

Sohn WM, Na BK, Cho SH, Park MY, Kim CH, Hwang MA, No KW, Yoon KB, Lim HC

The prevalence of Clonorchis sinensis metacercariae (CsMc) was examined in freshwater fish from the water systems of Seomjin-gang (River), the Republic of Korea. Total 1,604 fish from 7 local sites...
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Codon Usage Patterns of Tyrosinase Genes in Clonorchis sinensis

Bae YA

Codon usage bias (CUB) is a unique property of genomes and has contributed to the better understanding of the molecular features and the evolution processes of particular gene. In this...
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Toll-Like Receptor-Mediated Free Radical Generation in Clonorchis sinensis Excretory-Secretory Product-Treated Cholangiocarcinoma Cells

Bahk YY, Pak JH

Clonorchiasis, caused by direct contact with Clonorchis sinensis worms and their excretory-secretory products (ESPs), is associated with chronic inflammation, malignant changes in bile ducts, and even cholangiocarcinogenesis. Our previous report...
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C3H/He Mice as an Incompatible Cholangiocarcinoma Model by Clonorchis sinensis, Dicyclanil and N-Nitrosodimethylamine

Uddin MH, Li S, Jin Y, Choi MH, Jang JJ, Hong ST

Clonorchis sinensis is a Group-I bio-carcinogen, associated with cholangiocarcinoma (CCA). The hamster is the only experimental model of C. sinensis-mediated CCA, but we oblige another animal model. The present study...
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Prevalence of Clonorchis sinensis Infection among Residents along 5 Major Rivers in the Republic of Korea

Jeong YI, Shin HE, Lee SE, Cheun HI, Ju JW, Kim JY, Park MY, Cho SH

Clonorchis sinensis is currently the most important parasite affecting public health problems in the Republic of Korea. We investigated the prevalence of C. sinensis infection among residents living along 5...
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A Case of Malignant Biliary Stricture Mimicking Benign Stricture coincided with Clonorchis sinensis

Kim H, Han JH, Park SM, Kim JT, Jang JS, Lee HS, Lee S, Yeon M

Accurate and early diagnosis of indeterminate bile duct stricture is difficult. There are numerous cases suggesting similarity between benign tumors and malignancy. Therefore, meticulous evaluation with endoscopic retrograde cholangiopancreatography (ERCP),...
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Acute cholecystitis associated with Clonorchis sinensis infection

Oh JT, Kang DB, Jo HJ

Clonorchis sinensis is one of the most common causes of trematodiasis that is caused by the ingestion of raw fish contaminated with infective cysts. The adult flukes are predominantly present...
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A Study on the Prevalence of Clonorchis Sinensis and the Effects of Educational Program among Residents in the Basin of the Youngsan River, Korea

Kim C, So A, June KJ, Jung HY

PURPOSE: The goal of this study was to analyze the prevalence of Clonorchis sinensis infection in people living within 5 km of the Youngsan River basin, to develop an educational...
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Clonorchis Sinensis Infection Experience in Residents Living in Riverside Areas

Kim HG, June KJ, Kim SY, Park M, Kim C

PURPOSE: The purpose of this research was to describe clonorchis sinensis infection experience in high risk populations living in riverside areas. The research question was "How do local residents perceive...
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A Case of Chronic Urticaria Related to Clonorchis Sinensis

Hwang HH, Jung HH, Lee SJ, Jang GC, Sun YK

  • KMID: 2314578
  • Pediatr Allergy Respir Dis.
  • 2007 Dec;17(4):430-433.
Clonorchis sinensis infection is one of the most common parasitic infections that is widely distributed in Southern Korea as well as China, Japan, Taiwan, Hong kong, and Vietnam and countries...
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Infestation state of clonorchis sinensis in patients with pancreatobiliary diseases in ulsan: based on bile examination

Lee KY, Joo KR, Kim HS, Sin SJ, Lee HS, Yun TG, Choo YI, Park JH, Shin JW, Bang SJ, Kim DH, Park NH

  • KMID: 2252657
  • Korean J Med.
  • 2004 May;66(5):521-525.
BACKGROUND: Bile examination is believed to be the most precise method for detecting Clonorchis sinensis (CS) eggs. We carried out bile examination to evaluate infestation state of CS in patients...
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Evaluation of Diagnostic Utility of Intradermal Test for the Diagnosis of Clonorchis sinensis Infestation

Choi JC, Oh SH, Jeong HJ, Shin J, Park KH, Lee EY, Chang CL

  • KMID: 1611057
  • Korean J Clin Microbiol.
  • 2003 Sep;6(2):139-143.
BACKGROUND: The intradermal test for the screening of Clonorchis sinensis is difficult to interpret because the sensitivity and persistence rates of reactions after treatment are not well known. METHODS: Stool...
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Analysis of Parasite-Specific-Antibody Positive Patients for Clonorchis sinensis, Paragonimus westermani, Cysticercus and Sparganum using ELISA

Lee SH, Kim MN, Back BY, Choi JY, Kim TH, Hwang YS

  • KMID: 2305455
  • Korean J Lab Med.
  • 2003 Apr;23(2):126-131.
BACKGROUND: Although human parasitic infestations have decreased generally in Korea, Clonorchis sinensis, Paragonimus westermani, Cysticercus and Sparganum are still a serious concern due to their relatively high prevalence and severe...
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