Korean J Parasitol.  2002 Dec;40(4):173-176. 10.3347/kjp.2002.40.4.173.

Ultrastructural localization of 28 kDa glutathione S-transferase in adult Clonorchis sinensis

Affiliations
  • 1Department of Parasitology, Chung-Ang University College of Medicine, Seoul 156-756, Korea. hongsj@cau.ac.kr

Abstract

Glutathione S-transferase (28GST) with molecular mass of 28 kDa is an antioxidant enzyme abundant in Clonorchis sinensis. In adult C. sinensis, 28GST was localized in tegumental syncytium, cytons, parenchyma, and sperm tails examined by immunoelectron microscopy. C. sinensis 28GST was earlier found to neutralize bioreactive compounds and to be rich in eggs. Accordingly, it is suggested that 28GST plays important roles in phase II defense system and physiological roles in worm fecundity of C. sinensis.

Keyword

Clonorchis sinensis; Glutathione S-transferase; immunoelectron microscopy

MeSH Terms

Animals
Clonorchis sinensis/*enzymology
Glutathione Transferase/*metabolism/physiology
Immunohistochemistry
Microscopy, Immunoelectron
Molecular Weight
Support, Non-U.S. Gov't
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