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Long-term prognosis and management of hepatocellular carcinoma after curative treatment

Nishida N

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More evidence that direct acting antiviral therapy is safe and effective in cirrhosis and chronic kidney disease including peritoneal dialysis

Kwo P, Dronamraju D

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Phosphoinositide 3-kinase inhibitors are effective therapeutic drugs for the treatment of hepatocellular carcinoma?

Park JS, Bae SH

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Targeting epithelial-mesenchymal transition pathway in hepatocellular carcinoma

Song J

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Acute-on-chronic liver failure: A predictor of poor prognosis in patients with variceal bleeding or a risk factor for variceal bleeding?

Heo NY

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Liver-lung axes in alcohol-related liver disease

Arteel GE

Alcohol-related liver disease (ALD) and alcohol-related susceptibility to acute lung injury are the leading causes of morbidity and mortality due to chronic alcohol abuse. Most commonly, alcohol-induced injury to both...
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Lean non-alcoholic fatty liver disease: Is there a place for novel antidiabetics in the therapeutic management of this underappreciated “enemy”?

Patoulias D, Doumas M

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Programmed cell death in alcohol-associated liver disease

Miyata T, Nagy LE

Alcohol-associated liver disease (ALD), which ranges from mild disease to alcohol-associated hepatitis and cirrhosis, is the most prevalent type of chronic liver disease and a leading cause of morbidity and...
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Sarcopenia and blood myokine levels as prognostic biomarkers in patients with liver cirrhosis or hepatocellular carcinoma

Oh S, Lee J

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Predictors of steroid non-response and new approaches in severe alcoholic hepatitis

Sarin SK, Sharma S

Severe alcoholic hepatitis (SAH) remains a disease with high mortality. Steroid is the main stay and has been shown to give modest 28-day survival benefit in carefully selected patients, but...
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Precision medicine in nonalcoholic fatty liver disease: New therapeutic insights from genetics and systems biology

Sookoian S, Pirola CJ

Despite more than two decades of extensive research focusing on nonalcoholic fatty liver disease (NAFLD), no approved therapy for steatohepatitis—the severe histological form of the disease—presently exists. More importantly, new...
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The 14th International Symposium on Alcoholic Liver and Pancreatic Diseases and Cirrhosis (ISALPDC)

Kim DJ, Jeong WI, Tsukamoto H, Gao B

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Long non-coding RNAs in liver diseases: Focusing on nonalcoholic fatty liver disease, alcohol-related liver disease, and cholestatic liver disease

Han S, Zhang T, Kusumanchi P, Huda N, Jiang Y, Yang Z, Liangpunsakul S

Long non-coding RNAs (lncRNAs), a class of transcribed RNA molecules with the lengths exceeding 200 nucleotides, are not translated into protein. They can modulate protein-coding genes by controlling transcriptional and...
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Roles of the complement system in alcohol-induced liver disease

Zhou Y, Yuan G, Zhong F, He S

Alcohol-induced liver disease (ALD) is a complex disorder, with a disease spectrum ranging from steatosis to steatohepatitis, cirrhosis, and hepatocellular carcinoma. Although the pathogenesis of ALD is incompletely understood and...
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The lymphatic system in alcohol-associated liver disease

Kondo R, Iwakiri Y

The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the...
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The effect of moderate alcohol drinking in nonalcoholic fatty liver disease

Choi JH, Sohn W, Cho YK

Nonalcoholic fatty liver disease (NAFLD) is defined by fat accumulation in liver that is not caused by excessive alcohol consumption. Safe limits of alcohol consumption in NAFLD are usually defined...
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Evidence-based clinical advice for nutrition and dietary weight loss strategies for the management of NAFLD and NASH

Hydes TJ, Ravi S, Loomba R, E. Gray M

Nonalcoholic fatty liver disease (NAFLD) is the most common cause of chronic liver disease worldwide and affects approximately one third of adults in the United States. The disease is becoming...
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Alcohol and hepatocarcinogenesis

Taniai M

An excessive alcohol intake may result in fatty liver, acute/chronic hepatitis, cirrhosis, and lead to hepatocellular carcinoma (HCC). The aim of this review is to clarify the present condition and...
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Endoplasmic reticulum stress and autophagy dysregulation in alcoholic and non-alcoholic liver diseases

Kim YS, Kim SG

Alcoholic and non-alcoholic liver diseases begin from an imbalance in lipid metabolism in hepatocytes as the earliest response. Both liver diseases share common disease features and stages (i.e., steatosis, hepatitis,...
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Autophagy and liver cancer

Chao X, Qian H, Wang S, Fulte S, Ding WX

Autophagy is a highly conserved catabolic process that degrades cytosolic proteins and organelles via formation of autophagosomes that fuse with lysosomes to form autolysosomes, whereby autophagic cargos are degraded. Numerous...
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