Clin Mol Hepatol.
2020 Oct;26(4):633-638. 10.3350/cmh.2020.0179.
The lymphatic system in alcohol-associated liver disease
- Affiliations
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- 1Section of Digestive Diseases, Department of Internal Medicine, Yale University School of Medicine, New Haven, CT, USA
- 2Department of Pathology, Kurume University School of Medicine, Kurume, Japan
- KMID: 2507984
- DOI: http://doi.org/10.3350/cmh.2020.0179
Abstract
- The lymphatic system plays vital roles in interstitial fluid balance and immune cell surveillance. The effect of alcohol on the lymphatic system is poorly understood. This review article explores the role of the lymphatic system in the pathogenesis of alcohol-related disease including alcoholic liver disease (ALD) and the therapeutic potential of targeting hepatic lymphatics for the treatment of ALD.
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