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Nocturia: The circadian voiding disorder

Kim JW, Moon YT, Kim KD

Nocturia is a prevalent condition of waking to void during the night. The concept of nocturia has evolved from being a symptomatic aspect of disease associated with the prostate or...
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Is Advancing Circadian Rhythm the Mechanism of Antidepressants?

Lee HJ

Antidepressants usually require 2–8 weeks after drug administration to obtain a clinical response. In contrast, three fast-acting antidepressant treatments (sleep deprivation, electroconvulsive therapy, and ketamine) significantly reduced depressive symptoms within...
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Is the Circadian Rhythm Dysregulation a Core Pathogenetic Mechanism of Bipolar Disorder?

Lee HJ

Circadian rhythm is a periodic and continuous change in physiological, behavioral, and mental characteristics that occurs in most organisms on the Earth, because the Earth rotates in a 24-hour cycle....
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Sleep Disorder and Alcohol

Cho SB, Lee SH

The use of alcohol is associated with the development and worsening of sleep disorder. Alcohol is generally known to have a sedative effect, but it has an arousal or sedative...
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Excessive Daytime Sleepiness

Shin YK, Hong SC

  • KMID: 2394801
  • J Korean Med Assoc.
  • 2008 Mar;51(3):244-252.
Excessive daytime sleepiness (EDS) is a prevalent complaint among patients in psychiatric and medical care. Patients with EDS have often been misdiagnosed with depression due to their complaints of lack...
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Wnt and GSK3 Signaling Pathways in Bipolar Disorder: Clinical and Therapeutic Implications

Muneer A

The neurobiology of bipolar disorder, a chronic and systemic ailment is not completely understood. The bipolar phenotype manifests in myriad ways, and psychopharmacological agents like lithium have long term beneficial...
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Narcolepsy Variant Presented with Difficult Waking

Lee HW, Hong SB

  • KMID: 2317347
  • Sleep Med Psychophysiol.
  • 2000 Dec;7(2):115-119.
OBJECTIVES SUMMARY: A 20-year-old man was presented with a history of difficult waking for 10 years. He suffered from morning headache, chronic fatigue and mild daytime sleepiness but had no...
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The Relationship between Shift Work and Work-related Injuries among Korean Workers

Park TJ, Paek DM, Joh KO, Park JS, Cho SI

  • KMID: 2035674
  • Korean J Occup Environ Med.
  • 2012 Mar;24(1):52-60.
OBJECTIVES: The aim of this study was to evaluate the relationship between shift work and work-related injuries in a representative sample of Korean workers. METHODS: We used data from the Korean...
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Circadian Rhythm Hypotheses of Mixed Features, Antidepressant Treatment Resistance, and Manic Switching in Bipolar Disorder

Lee HJ, Son GH, Geum D

  • KMID: 2316293
  • Psychiatry Investig.
  • 2013 Sep;10(3):225-232.
Numerous hypotheses have been put forth over the years to explain the development of bipolar disorder. Of these, circadian rhythm hypotheses have gained much importance of late. While the hypothalamus-pituitary-adrenal...
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