Investig Clin Urol.  2016 May;57(3):165-173. 10.4111/icu.2016.57.3.165.

Nocturia: The circadian voiding disorder

• Kim JW
• Moon YT
• Kim KD

• KMID: 2426490
• DOI: http://doi.org/10.4111/icu.2016.57.3.165

Abstract

Nocturia is a prevalent condition of waking to void during the night. The concept of nocturia has evolved from being a symptomatic aspect of disease associated with the prostate or bladder to a form of lower urinary tract disorder. However, recent advances in circadian biology and sleep science suggest that it might be important to consider nocturia as a form of circadian dysfunction. In the current review, nocturia is reexamined with an introduction to sleep disorders and recent findings in circadian biology in an attempt to highlight the importance of rediscovering nocturia as a problem of chronobiology.

Keyword

Circadian clocks; Circadian rhythm; Lower urinary tract symptoms; Nocturia; Sleep wake disorders

MeSH Terms

Antidiuretic Agents/therapeutic use
Chronobiology Disorders/drug therapy/epidemiology/*physiopathology
Circadian Clocks/*physiology
Humans
Nocturnal Enuresis/drug therapy/epidemiology/*physiopathology
Prevalence
Sleep/physiology