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A Case of 5 alpha-reductase Deficiency in Infancy

Whang IT, Kim HS

  • KMID: 2193921
  • J Korean Soc Pediatr Endocrinol.
  • 1998 May;3(1):96-101.
5 alpha-reductase deficiency resulting in male pseudohermaphroditism is a rare disease characterized by clitoral-like phallus, bifid scrotum, urogenital sinus, testis cited in labioscrotal folds. Evaluation of plasma T/DHT ratios in...
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The Diagnostic Value of the HCG Stimulation Test for 5 alpha-reductase Deficiency in Children

Choi SK, Kim JW

  • KMID: 2289456
  • Korean J Urol.
  • 1989 Dec;30(6):856-859.
We evaluated 15 children with hypospadias or micropenis for the presence of 5 a-reductase deficiency. Serum testosterone and dihydrotestosterone(DHT) concentrations were measured before and 3 days after HCG stimulation. Also,...
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A case of 5 alpha reductase deficiency

Jang MJ, Oh SY, Choi SE, Oh HK, Kim DY, Choi YS

  • KMID: 1870367
  • Korean J Obstet Gynecol.
  • 2007 Mar;50(3):550-554.
5 alpha-reductase deficiency is a rare autosomal recessive disorder caused by mutations in the SRD5A2-gene, resulting in absent or diminished dihydrotestosterone (DHT) formation and, hence, in an underdevelopment of the...
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The Efficacy of Combination Therapy of 5 alpha -Reductase Inhibitor and of-Adrenergic Blocker in Benign Prostate Hyperplasia

Noh JH, Oh BR, Park YI

  • KMID: 2290272
  • Korean J Urol.
  • 1998 Dec;39(12):1190-1196.
PURPOSE: Benign prostate hyperplasia(BPH) can be treated with alpha1-adrenergic blocker that relaxes prostate smooth muscle or 5 alpha-reductase inhibitor that reduces serum dirtydrotestosterone. The efficacy of the combination of...
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The Antihyperplastic Effect of Oral Catechin Ingestion in a Rat Model of Benign Prostatic Hyperplasia

Park DJ, Kang SH, Cho YH

PURPOSE: Benign prostatic hyperplasia (BPH) is one of the common diseases in elderly men. Recently, the old-aged population has increased, with the interest in the clinical importance of BPH ever...
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Patient's Factors Correlated with Prostate Volume Recovery after 5 Alpha Reductase Inhibitor Discontinuation

Choi K, Kim B, Cho IC, Min SK

PURPOSE: The 5 alpha reductase inhibitor (5ARI) reduces the size of the prostate and alleviates lower urinary tract symptoms. After stopping 5ARI, the prostate quickly recovers to its pre-medication size....
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Promoting Effect of a Mixture of 8 Herbal Extracts (SPELA 707) on Hair Growth

Choi EY, Park SN, Park SU, Choi S, Ro BI, Chung MH

  • KMID: 2285280
  • Korean J Physiol Pharmacol.
  • 2003 Apr;7(2):91-96.
In Korean folk medicine, several herbs, Glycyrrhizae Radix, Persicae Semen, Salviae Radix, Angelicae Gigantis Radix, Zanthoxyli Fructus, Ginseng Radix Alba, Cnidii Rhizoma, and Carthami Flos, are known to enhance blood...
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Post-marketing Surveillance of the Safety of Dutasteride Prescribed to Korean Patients with Benign Prostate Hyperplasia

Kim JH, Bae JY, Oh SY, Lee YS

  • KMID: 2334523
  • J Korean Soc Clin Pharmacol Ther.
  • 2012 Jun;20(1):85-94.
BACKGROUND: Dutasteride is an inhibitor of both types I and II 5 alpha-reductase and was approved in Korea in April 2004. This post-marketing surveillance was to assess the safety of...
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Prevention of Prostate Cancer

Chung JI

  • KMID: 2341017
  • J Korean Med Assoc.
  • 2010 Feb;53(2):135-141.
Prostate cancer can be prevented more easily than other types of cancers, thanks to the following reasons: The presence of precursor lesions, longer doulbling time of cancerous cells, high incidence...
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Effects of Finasteride and Castration on Rat Ventral Prostate

Oh BR, Ahn KY, Kwon DD, Lim JH, Park KS, Ryu SB, Park YI

  • KMID: 1859349
  • Korean J Androl.
  • 2000 Apr;18(1):47-53.
PURPOSE: To compare the mechanism of cell loss and changes in the ventral prostate of young adult Sprague-Dawley rats after treatment with finasteride, a potent 5 alpha-reductase inhibitor, or castration. MATERIALS...
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RE-ORGA, a Korean Herb Extract, Can Prevent Hair Loss Induced by Dihydrotestosterone in Human Dermal Papilla Cells

Kang MG, Park D, Han HY, Shim H, Hong Y, Moon J, Yoon S, Kwon B

BACKGROUND: Androgenic alopecia (AGA) is the most common type of hair loss. It is likely inherited genetically and is promoted by dihydrotestosterone. 5α-reductase has been proven a good target through...
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Pathologic Characteristics and Prognosis of Pathologic T0 Prostate Cancer

Lee SR, Ham WS, Kim WT, Ju HJ, Lee JS, Choi YD

  • KMID: 2311874
  • Korean J Urol.
  • 2009 Mar;50(3):229-236.
PURPOSE: We evaluated the pathologic characteristics and prognosis of pathologic T0 (pT0) prostate cancer (PC). MATERIALS AND METHODS: Of 1,196 consecutive men who underwent radical prostatectomy (RP) between January 1992 and...
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Korean Urologist's View of Practice Patterns in Diagnosis and Management of Benign Prostatic Hyperplasia: A Nationwide Survey

Oh CY, Lee SH, Yoo SJ, Chung BH

PURPOSE: In Korea, there was no specific guidelines for the management of benign prostatic hyperplasia (BPH). We reviewed the practice patterns of Korean urologists in the management of BPH and...
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Prostate-Specific Antigen Test Interval according to Baseline Prostate-Specific Antigen and Age

Kwon MS, Oh CY, Yoo CH, Kim SI, Kim SJ, Kim DJ, Kim YS, Kim CI, Kim HS, Seong DH, Song KH, Song YS, Yang WJ, Lee DH, Cheon SH, Cho IR, Chung BH, Choi YD, Hong SJ, Im H, Cho JS

  • KMID: 2314736
  • Korean J Urol.
  • 2009 Nov;50(11):1059-1065.
PURPOSE: The optimal interval at which to repeat prostate-specific antigen (PSA) measurement is controversial. We evaluated the probability of the serum PSA value increasing above specific cutoff values (4.0 ng/ml,...
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