- Expression Correlation Between NM23/NDP Kinase and c-myc in NM23/NDP Kinase Transfectant Cell Lines
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Lee KY, Song DW, Kim DJ, Kim DS, Chang SI, Lee IH
- KMID: 2283063
- Korean J Phys Anthropol.
- 1998 Jun;11(1):33-40.
Since Steeg, et al.(1988) identified NM23/NDP kinase as non -metastasis gene, other multiple functions of have reported. One of them, Postel, et al.(1993) suggested that transcription factor PuF, being encoded... -
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- Nicotine Down-regulates COL1A2 Promoter in Cultured Human Skin Fibroblasts
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Kim BC, Kim JO, Ryoo YW, Lee KS
- KMID: 2163884
- Ann Dermatol.
- 2001 Sep;13(3):153-157.
- doi: 10.5021/ad.2001.13.3.153
BACKGROUND: It has become generally accepted that cigarette smoking contributes to accelerated coronary and peripheral vascular disease, pulmonary fibrosis and periodontal disease. Moreover, it has been postulated that cigarette smoking... -
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- The Effect of Dehydroepiandrosterone on Expression of Elastin in Cultured Skin Fibroblasts
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Kim CD, Ryoo YW, Lee KS
- KMID: 2250813
- Korean J Dermatol.
- 2002 Jun;40(6):599-606.
BACKGROUND: Dehydroepiandrosterone(DHEA) and its sulfate ester dehydro- epiandrosterone sulfate(DHEA-S) are the steroids secreted most abdundantly by the human adrenal gland, but the physiologic role remains uncertain. Elastin is one of... -
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- Effects of Ultraviolet A and B Irradiation on the Transcriptional Regulation of Stromelysin-1 Gene in Human Fibroblast Cultures
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Kim BC, Park JH, Lee KS
- KMID: 2383028
- Ann Dermatol.
- 1999 Oct;11(4):225-231.
- doi: 10.5021/ad.1999.11.4.225
BACKGROUND: Sun exposure and therapeutic irradiation have been shown to induce alterations in extracellular matrix (ECM) proteins, including elastin, glycosaminoglycan and collagens. The integrity of the connective tissue mainly depends... -
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- The Effect of Nicotine on Elastin Gene Expression in Cultured Skin Fibroblasts
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Kim JO, Ryoo YW, Lee KS
- KMID: 1595385
- Korean J Dermatol.
- 2001 May;39(5):529-535.
BACKGROUND: The elastic fibers are a major fibrillar component of the extracellular matrix of several organs, and their presence provides elastic properties to these tissues. A variety of cytokines, growth... -
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- Interferon-gamma upregulates the stromelysin-1 gene expression by human skin fibroblasts in culture
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Lee KS, Ryoo YW, Song JY
- KMID: 754989
- Exp Mol Med.
- 1998 Jun;30(2):59-64.
The equilibrium between deposition and degradation of extracellular matrix(ECM) is essential to normal tissue development and repair of wound or inflammatory responses. It has recently become apparent that several cytokines and growth factors... -
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- Transcriptional activation of insulin-like growth factor binding protein 6 by 17beta-estradiol in SaOS-2 cells
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Zhao YY, Guo L, Zhao XJ, Liu H, Lei T, Ma DJ, Gao XY
- KMID: 1058022
- Exp Mol Med.
- 2009 Jul;41(7):478-486.
- doi: 10.3858/emm.2009.41.7.053
Osteoblasts can synthesize the insulin-like growth factors (IGFs) and the IGF-binding proteins (IGFBPs), which may either enhance or attenuate IGF-stimulated bone cell proliferation. Since estrogen induced osteoblastic differentiation and proliferation... -
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- Cloning and characterization of 5'-upstream region of human phospholipase C-beta2 gene
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Yun ES, Lee SJ, Kim MJ, Ryu SH, Suh PG
- KMID: 1085743
- Exp Mol Med.
- 2001 Jun;33(2):76-82.
5'-upstream region of the phospholipase C-beta2 gene, 810 bp, was cloned and characterized. S1 nuclease mapping and primer extension analyses revealed that a single transcriptional start site locates at 284... -
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- Improved expression by cytomegalovirus promoter/enhancer and behavior of vascular endothelial growth factor gene after myocardial injection of naked DNA
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Jeong JO, Byun JH, Jeon ES, Gwon HC, Lim YS, Park JW, Yeo SJ, Lee YJ, Kim SY, Kim DK
- KMID: 931878
- Exp Mol Med.
- 2002 Sep;34(4):278-284.
Direct injection of the vascular endothelial growth factor (VEGF) gene plasmid DNA into the myocardium was shown to induce development of new blood vessels to increase the circulation in... -
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- Genomic structure of the regulatory region of the voltage-gated calcium channel alpha 1D
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Kim HL, Chang YJ, Lee SM, Hong YS
- KMID: 755016
- Exp Mol Med.
- 1998 Dec;30(4):246-251.
In excitable and endocrine organs, calcium influxes through the L-type voltage-gated calcium channel (VGCC) which is composed of four (alpha 1, alpha 2, beta, and gamma) subunits. Temporal and spatial... -
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- Characterization of regulatory elements on the promoter region of human ATP-citrate lyase
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Moon YA, Kim KS, Cho UH, Yoon DJ, Park SW
- KMID: 1029940
- Exp Mol Med.
- 1999 Jun;31(2):108-114.
ATP-citrate lyase (ACL), an enzyme catalyzing the first step in biosynthesis of fatty acids, is induced during the lipogenesis and cholesterologenesis. We demonstrate that the region -213 to -128 of human ACL... -
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- American Ginseng Transcriptionally Activates p21 mRNA in Breast Cancer Cell Lines
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Duda RB, Kang SS, Archer SY, Meng S, Hodin RA
- KMID: 1721175
- J Korean Med Sci.
- 2001 Dec;16(Suppl):S54-S60.
- doi: 10.3346/jkms.2001.16.S.S54
American ginseng (AG) has been demonstrated to inhibit breast cancer cell growth in vitro. p21 protein, a universal cell cycle inhibitor, binds cyclin-CDK complexes, an important mechanism in cell cycle... -
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