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Renal involvement in pediatric rheumatologic diseases

Kim SH

Pediatric rheumatologic diseases are rare systemic diseases that can involve various organs, including the kidneys. Each rheumatologic disease can exhibit characteristic renal involvement, which requires proper treatment and diagnosis. In...
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Genetic analysis using whole-exome sequencing in pediatric chronic kidney disease: a single center's experience

Purpose: Chronic kidney disease (CKD) has various underlying causes in children. Identification of the underlying causes of CKD is important. Genetic causes comprise a significant proportion of pediatric CKD cases. Methods:...
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Mechanism, clinical consequences, and management of dyslipidemia in children with nephrotic syndrome

Baek HS

Dyslipidemia in nephrotic syndrome (NS) is often characterized by marked increases in the levels of total cholesterol, triglycerides, low-density lipoprotein cholesterol, and other lipoproteins, such as very low-density lipoprotein, intermediate-density...
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Recurrent hemolytic uremic syndrome caused by DGKE gene mutation: a case report

Shin BS, Ahn YH, Kang HG

Atypical hemolytic uremic syndrome (aHUS) is a rare disease characterized by microangiopathic hemolytic anemia, thrombocytopenia, and acute kidney injury without any association with preceding diarrhea. Dysregulation of the complement system...
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Alport syndrome: new advances in the last decade

Kim JH

Alport syndrome (AS) is a progressive hereditary nephritis that is often accompanied by sensorineural hearing loss and ocular abnormalities. It is inherited in three modes of X-linked (XLAS), autosomal recessive...
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Management strategies for congenital isolated hydronephrosis and the natural course of the disease

Jung J, Lee JH, Kim KS, Song SH, Moon DH, Yoon HM, Cho YA, Park YS

Congenital isolated hydronephrosis encompasses a spectrum of physiologic states that spontaneously resolve and pathologic obstruction that necessitates surgical intervention. Distinguishing patients whose condition will resolve, those who will require stringent...
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Idiopathic infantile hypercalcemia with severe nephrocalcinosis, associated with CYP24A1 mutations: a case report

Yoo J, Kang HG, Ahn YH

Nephrocalcinosis often occurs in infants and is caused by excessive calcium or vitamin D supplementation, neonatal primary hyperparathyroidism, and genetic disorders. Idiopathic infantile hypercalcemia (IIH), a rare cause of nephrocalcinosis,...
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Delta neutrophil index as a predictor of vesicoureteral reflux in children with febrile urinary tract infection

Kim JE, Oh JS, Yoon JM, Ko KO, Cheon EJ

Purpose: Delta neutrophil index (DNI) indicates immature granulocytes in peripheral blood and has been confirmed to be effective as a prognostic factor for neonatal sepsis. Also, it has been reported...
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Predictors of renal scars in infants with recurrent febrile urinary tract infection: a retrospective, single-center study

Han JH, Rhie S, Lee JH

Purpose: To determine predictive factors for detecting renal parenchymal damages (RPDs) in infants with recurrent febrile urinary tract infection (fUTI). Methods: From January 2015 to December 2021, 102 infants with recurrent...
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