- IL-10 Mediates Rosiglitazone-Induced Kidney Protection in Cisplatin Nephrotoxicity
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Kim MG, Yang HN, Kim HW, Jo SK, Cho WY, Kim HK
- KMID: 1792925
- J Korean Med Sci.
- 2010 Apr;25(4):557-563.
- doi: 10.3346/jkms.2010.25.4.557
Cisplatin, a major anti-neoplastic drug, is known to be nephrotoxic and inflammation-inducing. A peroxisome proliferator-activated receptor gamma agonist, regulating lipid metabolism, has known to have anti-inflammatory effect, but the protection... -
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- Chemokine Signaling Pathway Involved in CCL2 Expression in Patients with Rheumatoid Arthritis
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Zhang L, Yu M, Deng J, Lv X, Liu J, Xiao Y, Yang W, Zhang Y, Li C
- KMID: 2366358
- Yonsei Med J.
- 2015 Jul;56(4):1134-1142.
- doi: 10.3349/ymj.2015.56.4.1134
PURPOSE: Rheumatoid arthritis (RA) is an inflammatory joint disorder, the progression of which leads to the destruction of cartilage and bone. Chemokines are involved in RA pathogenesis. In this study,... -
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- A 24 kDa Excretory-Secretory Protein of Anisakis simplex Larvae Could Elicit Allergic Airway Inflammation in Mice
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Park HK, Cho MK, Park MK, Kang SA, Kim YS, Kim KU, Lee MK, Ock MS, Cha HJ, Yu HS
- KMID: 1715742
- Korean J Parasitol.
- 2011 Dec;49(4):373-380.
- doi: 10.3347/kjp.2011.49.4.373
We have reported that a 24 kDa protein (22U homologous; As22U) of Anisakis simplex larvae could elicit several Th2-related chemokine gene expressions in the intestinal epithelial cell line which means... -
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- Change of connexin 37 in allergen-induced airway inflammation
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Park SJ, Lee KS, Kim SR, Min KH, Lee KY, Choe YH, Park SY, Hong SH, Lee YC
- KMID: 1090966
- Exp Mol Med.
- 2007 Oct;39(5):629-640.
Gap junction channels formed with connexins directly link to the cytoplasm of adjacent cells and have been implicated in intercellular signaling. Connexin 37 (Cx37) is expressed in the gas-exchange region... -
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- SP600125, a selective JNK inhibitor, aggravates hepatic ischemia-reperfusion injury
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Lee KH, Kim SE, Lee YS
- KMID: 1110125
- Exp Mol Med.
- 2006 Aug;38(4):408-416.
c-Jun N-terminal kinase (JNK) is activated during hepatic reperfusion, and JNK inhibitors are known to protect other major organs from ischemia-reperfusion (I/R) injury. We attempted to determine the effect of... -
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- Blockade of airway inflammation and hyper-responsiveness by an angiopoietin-1 variant, COMP-Ang1
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Lee KS, Lee KY, Kim SR, Park HS, Park SJ, Min KH, Cho CH, Koh GY, Park HS, Lee YC
- KMID: 1091068
- Exp Mol Med.
- 2007 Dec;39(6):733-745.
Inflammation of the asthmatic airway is usually accompanied by increased vascular permeability and plasma exudation. Angiopoietin-1 (Ang1) has potential therapeutic applications in preventing vascular leakage. Recently, we developed a soluble,... -
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