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Comparison and Contrast of Bone and Dentin in Genetic Disorder, Morphology and Regeneration: A Review

Kim J, Lee G, Chang WS, Ki Sh, Park JC

The bone and dentin have distinct healing processes. The healing process of bones is regenerative, as newly formed tissues are morphologically and functionally similar to the original bone structures. In...
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Temporal Volume Change of Cavernous Sinus Cavernous Hemangiomas after Gamma Knife Surgery

Cho JM, Sung KS, Jung IH, Chang WS, Jung HH, Chang JH

Cavernous hemangiomas occur very rarely in the cavernous sinus. This study aimed to evaluate the efficacy of Gamma Knife surgery (GKS) on cavernous sinus cavernous hemangioma (CSCH) and to analyze...
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Risk Factors and Comorbidities Associated With the Allergic Rhinitis Phenotype in Children According to the ARIA Classification

Jung S, Lee SY, Yoon J, Cho HJ, Kim YH, Suh DI, Yang SI, Kwon JW, Jang GC, Sun YH, Woo SI, Youn YS, Park KS, Lee E, Cho HJ, Kook MH, Yi HR, Chung HL, Kim JH, Kim HY, Jung JA, Woo HO, Lee JK, Chang WS, Do NH, Cho H, Hong SJ

PURPOSE: Data are lacking on the association between the allergic rhinitis (AR) phenotype and sensitization to specific allergens or bronchial hyperresponsiveness (BHR) in children. We here investigated risk factors and...
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Outcomes of Intrathecal Baclofen Therapy Compared With Deep Brain Stimulation in a Patient With Dystonic Cerebral Palsy: A Case Report

Chae M, Hong S, Jung NY, Chang WS, Cho SR

Deep brain stimulation (DBS) in internal globus pallidus is considered to be a good option for controlling generalized dystonia in patients with this condition. In this relation, it is known...
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The Potential Usefulness of Magnetic Resonance Guided Focused Ultrasound for Obsessive Compulsive Disorders

Jung HH, Chang WS, Kim SJ, Kim CH, Chang JW

Obsessive compulsive disorder is a debilitating condition characterized by recurrent obsessive thoughts and compulsive reactions. A great portion of the obsessive compulsive disorder (OCD) patients are managed successfully with psychiatric...
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Effect of Placenta-Derived Mesenchymal Stem Cells in a Dementia Rat Model via Microglial Mediation: a Comparison between Stem Cell Transplant Methods

Cho JS, Lee J, Jeong DU, Kim HW, Chang WS, Moon J, Chang JW

PURPOSE: Loss of cholinergic neurons in the hippocampus is a hallmark of many dementias. Administration of stem cells as a therapeutic intervention for patients is under active investigation, but the...
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Prevalence of Self-reported Allergic Diseases and IgE Levels: A 2010 KNHANES Analysis

Park HJ, Kim EJ, Yoon D, Lee JK, Chang WS, Lim YM, Park JW, Lee JS

PURPOSE: The prevalence of allergic diseases is known to be associated with both demographic and environmental factors. Herein, we aimed to determine significant factors associated with the prevalence of allergic...
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Focused ultrasound treatment for central nervous system disease: neurosurgeon's perspectives

Chang WS, Chang JW

The concept of focused ultrasound (FUS) and its application in the field of medicine have been suggested since the mid-20th century. However, the clinical applications of this technique in central...
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Hearing Restoration in Neurofibromatosis Type II Patients

Lee JM, Chang JW, Choi JY, Chang WS, Moon IS

Patients with neurofibromatosis type II will eventually succumb to bilateral deafness. For patients with hearing loss, modern medical science technology can provide efficient hearing restoration through a number of various...
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Age-Related Changes in Immunological Factors and Their Relevance in Allergic Disease Development During Childhood

Chang WS, Kim EJ, Lim YM, Yoon D, Son JY, Park JW, Hong SJ, Cho SH, Lee JS

PURPOSE: Allergic diseases are triggered by Th2-mediated immune reactions to allergens and orchestrated by various immunological factors, including immune cells and cytokines. Although many reports have suggested that childhood is...
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Optimal Treatment Decision for Brain Metastases of Unknown Primary Origin: The Role and Timing of Radiosurgery

Han HJ, Chang WS, Jung HH, Park YG, Kim HY, Chang JH

BACKGROUND: Up to 15% of all patients with brain metastases have no clearly detected primary site despite intensive evaluation, and this incidence has decreased with the use of improved imaging...
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Basal Forebrain Cholinergic Deficits Reduce Glucose Metabolism and Function of Cholinergic and GABAergic Systems in the Cingulate Cortex

Jeong DU, Oh JH, Lee JE, Lee J, Cho ZH, Chang JW, Chang WS

PURPOSE: Reduced brain glucose metabolism and basal forebrain cholinergic neuron degeneration are common features of Alzheimer's disease and have been correlated with memory function. Although regions representing glucose hypometabolism in...
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Dose-dependent Changes in Gait Pattern after Intrathecal Baclofen Bolus Injection in Adult Ambulatory Cerebral Palsy: A Case Report

Shin YK, Kim AR, Chang JW, Chang WS, Lee DS, Cho SR

Intrathecal baclofen (ITB) therapy has been proven to reduce severe spasticity in cerebral palsy (CP). However, few results reported the objective gait pattern change after ITB bolus injection in adult...
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Effect of Subthalamic Deep Brain Stimulation on Levodopa-Induced Dyskinesia in Parkinson's Disease

Kim JH, Chang WS, Jung HH, Chang JW

PURPOSE: To evaluate the effect of bilateral subthalamic nucleus (STN) deep brain stimulation (DBS) on levodopa-induced peakdose dyskinesia in patients with Parkinson's disease (PD). MATERIALS AND METHODS: A retrospective review was...
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H5N8 Highly Pathogenic Avian Influenza in the Republic of Korea: Epidemiology During the First Wave, from January Through July 2014

Yoon H, Moon OK, Jeong W, Choi J, Kang YM, Ahn HY, Kim JH, Yoo DS, Kwon YJ, Chang WS, Kim MS, Kim DS, Kim YS, Joo YS

Objectives This study describes the outbreaks of H5N8 highly pathogenic avian influenza (HPAI) in Korea during the first wave, from January 16, 2014 through July 25, 2014. Its purpose is to...
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Long-Term Results of Gamma Knife Radiosurgery for Intracranial Meningioma

Jang CK, Jung HH, Chang JH, Chang JW, Park YG, Chang WS

BACKGROUND: The predominant treatment modality for meningioma is surgical resection. However, gamma knife radiosurgery is also an important treatment modality for meningioma that is small or cannot be completely removed...
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Delayed Dural Arteriovenous Fistula after Microvascular Decompression for Hemifacial Spasm

Kim SH, Chang WS, Jung HH, Chang JW

Dural arteriovenous fistula (AVF) is very rare, acquired lesion that may present with intracranial hemorrhage or neurological deficits. The etiology is not completely understood but dural AVF often has been...
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Two-Year Outcomes of Deep Brain Stimulation in Adults With Cerebral Palsy

Kim AR, Chang JW, Chang WS, Park ES, Cho SR

  • KMID: 2407881
  • Ann Rehabil Med.
  • 2014 Apr;38(2):209-217.
OBJECTIVE: To investigate the effect of deep brain stimulation (DBS) on reducing dystonia and disability in adults with cerebral palsy (CP) and to compare the therapeutic outcomes between primary dystonia...
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Factors Related to Outcomes of Subthalamic Deep Brain Stimulation in Parkinson's Disease

Kim HY, Chang WS, Kang DW, Sohn YH, Lee MS, Chang JW

OBJECTIVE: Subthalamic nucleus (STN) deep brain stimulation (DBS) is an effective treatment of choice for patients with advanced idiopathic Parkinson's disease (PD) who have motor complication with medication. The objectives...
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Anomalous Separate Origin of Left Anterior Descending Coronary Artery: Presented as Acute Anterior Myocardial Infarction

Hong MY, Shin DH, Kwon JH, Chang WS, Choi KU, Song YA, Oh KH, Lee JH

Coronary artery anomalies are rare presentations in primary percutaneous coronary interventions of acute myocardial infarction. Herein, we report the case of a 59-year-old man with acute anterior myocardial infarction who...
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