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The mechanism of antiproliferative effect of desferrioxamine on human hepatoma cell lines

Kim DY, Kim WH, Kang JK, Park IS, Kwon OH

We investigated the effect of desferrioxamine (DFO), an iron chelator, on the DNA synthesis and the cell cycle of cultured hepatoma cells. Using Hep 3B cells as the hepatoma cell...
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Iron-induced cytotoxicity in cultured rat retinal neurons

Sohn J, Yoon YH

Oxidative stress has been proposed as a major injury mechanism in the central nervous system including the retina. In this study, as an initial attempt to study the mechanism of...
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Partial purification and characterization of a novel murine factor that augments the expression of class I MHC antigens on tumor cells

Puri N, Saxena RK

  • KMID: 754994
  • Exp Mol Med.
  • 1998 Jun;30(2):93-99.
A soluble factor which augments the expression of major histocompatibility complex class I (MHC I) antigens on a number of murine tumor cell lines, has been isolated from the culture supernatants of...
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Hydrogen peroxide mediates doxorubicin-induced transglutaminase 2 expression in PC-14 human lung cancer cell line

Han JA, Park SC

  • KMID: 1029936
  • Exp Mol Med.
  • 1999 Jun;31(2):83-88.
Increased expression of Transglutaminases 2 (TGase 2, TGase C) was observed in PC-14 human lung cancer cells in association with doxorubicin resistance and the reduction of the enzyme expression was correlated with...
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Effects of iodinated fatty acid ester on human hepatocellular carcinoma cells

Kim H, Park C, Lee YB, Yoo HS, Park JH, Lee WY

The interaction between Lipiodol and cells was studied by treating Lipiodol in a human hepatocellular carcinoma cell line(Hep) and mouse fibroblast cell line (L929). Irregular, sustained radioactivity was released from...
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Effect of anticancer drugs and desferrioxamine in combination with radiation on hepatoma cell lines

Kim WH, Chon CY, Moon YM, Kang JK, Park IS, Choi HJ

Several anticancer chemotherapeutic agents (5-fluorouracil, adriamycin and cisplatinum) and desferrioxamine, an iron chelator, were tested with regard to cytotoxicity and to the combined effect on radiation induced cell killing using...
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Stimulation of Cl- secretion by AlF4- and vanadate in T84 cells

Hwang TH, Jung JS, Bae HR, Yun I, Lee SH

We investigated the mechanism of Cl- secretion by fluoroaluminate(AlF4-) and sodium orthovanadate(vanadate) using the human colonic T84 cell line. T84 cell monolayers grown on collagen-coated filters were mounted in Ussing...
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Altered Gene Expression Profile After Exposure to Transforming Growth Factor beta1 in the 253J Human Bladder Cancer Cell Line

Lee C, Lee SH, Kim DS, Jeon YS, Lee NK, Lee SE

PURPOSE: Transforming growth factor beta1 (TGF-beta1) inhibits the growth of bladder cancer cells and this effect is prominent and constant in 253J bladder cancer cells. We performed a microarray analysis...
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Triton X-100 induces apoptosis in human hepatoma cell lines

Ahn JM, Kim SJ, Kim H, Park C, Kim WH, Park JH

The detergent Triton X-100 was used to establish a model for apoptosis in hepatoma cell lines. The electrophoresis of DNA extracted from 0.01% Triton X-100 treated hepatoma cell...
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Combined use of tamoxifen, cyclosporin A, and verapamil for modulating multidrug resistance in human hepatocellular carcinoma cell lines

Kim JH, Chung JB, Park IS, Kim BS, Yoo NC, Choi JH, Roh JK, Kim HS, Kwon OH, Lee KS, Kim BS

The intensive use of chemotherapeutic agents for the treatment of cancer has resulted in the cure or improved survival of many patients. But unfortunately, many cancers including human hepatocellular carcinoma...
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Thermo-stability and antitumor activity on colon cancer cell lines of monoclonal anti-CEA antibody-saporin immunotoxin

Manosroi J, Kleist SV, Manosroi A, Grunert F

Eight saporin peaks were obtained from the purification of seed extracts of Saponaria officinalis L. Saporin peak No. 6 (SAP-6) showed the highest activity in the inhibition of protein...
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