- Prognostic Significance of CD109 Expression in Patients with Ovarian Epithelial Cancer
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Kim SY, Choi KU, Hwang C, Lee HJ, Lee JH, Shin DH, Kim JY, Sol MY, Kim JH, Kim KH, Suh DS, Kwon BS
- KMID: 2454604
- J Pathol Transl Med.
- 2019 Jul;53(4):244-252.
- doi: 10.4132/jptm.2019.04.16
BACKGROUND: Ovarian epithelial cancer (OEC) is the second-most common gynecologic malignancy. CD109 expression is elevated in human tumor cell lines and carcinomas. A previous study showed that CD109 expression is... -
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- Long Non-Coding RNA TUG1 Promotes Proliferation and Inhibits Apoptosis of Osteosarcoma Cells by Sponging miR-132-3p and Upregulating SOX4 Expression
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Li G, Liu K, Du X
- KMID: 2418785
- Yonsei Med J.
- 2018 Mar;59(2):226-235.
- doi: 10.3349/ymj.2018.59.2.226
PURPOSE: Long non-coding RNA taurine upregulated gene 1 (TUG1) is reported to be a vital regulator of the progression of various cancers. This study aimed to explore the exact roles... -
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- Antimicrobial and Antitumor Photodynamic Effects of Phleichrome from the Phytopathogenic Fungus Cladosporium Phlei
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So KK, Chun J, Kim DH
- KMID: 2434574
- Mycobiology.
- 2018 Dec;46(4):448-451.
- doi: 10.1080/12298093.2018.1551599
Fungal perylenequinones have photodynamic activity and are promising photosensitizers for photodynamic therapy (PDT). Here, we investigated the bactericidal and antitumor activities of phleichrome from the fungal perylenequinone family in vitro.... -
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- 14-3-3ζ Overexpression is Associated with Poor Prognosis in Ovarian Cancer
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Kim HJ, Sung SH, Kim CY, Bae MK, Cho MS, Kim YH, Kim SC, Ju W
- KMID: 2418848
- Yonsei Med J.
- 2018 Jan;59(1):51-56.
- doi: 10.3349/ymj.2018.59.1.51
PURPOSE: 14-3-3ζ regulates cell signaling, cell cycle progression, and apoptosis, and its overexpression is associated with disease recurrence and poor clinical outcomes in some solid tumors. However, its clinicopathological role... -
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- TRIM56 Suppresses Multiple Myeloma Progression by Activating TLR3/TRIF Signaling
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Chen Y, Zhao J, Li D, Hao J, He P, Wang H, Zhang M
- KMID: 2418847
- Yonsei Med J.
- 2018 Jan;59(1):43-50.
- doi: 10.3349/ymj.2018.59.1.43
PURPOSE: Tripartite-motif-containing protein 56 (TRIM56) has been found to exhibit a broad antiviral activity, depending upon E3 ligase activity. Here, we attempted to evaluate the function of TRIM56 in multiple... -
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- Pseudolaric Acid B Inhibits Proliferation, Invasion and Epithelial-to-Mesenchymal Transition in Human Pancreatic Cancer Cell
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Li X, Zhao X, Song W, Tian Z, Yang L, Niu Q, Zhang Q, Xie M, Zhou B, Xu Y, Wu J, Zhang C
- KMID: 2418844
- Yonsei Med J.
- 2018 Jan;59(1):20-27.
- doi: 10.3349/ymj.2018.59.1.20
PURPOSE: This study was aimed to investigate the effect of pseudolaric acid B (PAB) on proliferation, invasion and epithelial-to-mesenchymal transition (EMT) in pancreatic cancer cells and to explore the possible... -
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- Gene Expression Profiling of Hepatocellular Carcinoma Derived Cancer Stem Like Cell under Hypoxia
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Choi SH, Lee SW, Ok M, Kim KS, Kim S, Ahn SH
- KMID: 2418927
- Yonsei Med J.
- 2017 Sep;58(5):925-933.
- doi: 10.3349/ymj.2017.58.5.925
PURPOSE: Cancer stem like cells (CSCs), with unlimited self-renewal potential and other stem cell characteristics, occur in several cancers including hepatocellular carcinoma (HCC). Although CSCs can initiate tumors, malignant proliferation,... -
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- Down-Regulation of TGF-β Expression Sensitizes the Resistance of Hepatocellular Carcinoma Cells to Sorafenib
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Kang D, Han Z, Oh GH, Joo Y, Choi HJ, Song JJ
- KMID: 2418924
- Yonsei Med J.
- 2017 Sep;58(5):899-909.
- doi: 10.3349/ymj.2017.58.5.899
PURPOSE: Sorafenib, a multikinase inhibitor, is the standard therapy for patients with advanced-stage hepatocellular carcinoma (HCC). However, resistance develops to the treatment, therefore, we tried to unravel the underlying mechanism... -
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- Programmed death-1 pathway blockade produces a synergistic antitumor effect: combined application in ovarian cancer
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Zhu X, Lang J
- KMID: 2413224
- J Gynecol Oncol.
- 2017 Sep;28(5):e64.
- doi: 10.3802/jgo.2017.28.e64
Programmed death-1 (PD-1) and its ligand are part of the immune checkpoint pathway that down-regulates effector T cells in immune response, thereby causing immune suppression. The PD-1/programmed death-ligand 1 (PD-L1)... -
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- Estrogen receptor-α, progesterone receptor, and c-erbB/HER-family receptor mRNA detection and phenotype analysis in spontaneous canine models of breast cancer
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Kabir FM, DeInnocentes P, Agarwal P, Mill CP, Riese DJ, Bird RC
- KMID: 2412567
- J Vet Sci.
- 2017 Jun;18(2):149-158.
- doi: 10.4142/jvs.2017.18.2.149
Well characterized, stable, p16-defective canine mammary cancer (CMT) cell lines and normal canine mammary epithelial cells were used to investigate expression of the major breast cancer-specific hormone receptors estrogen receptor... -
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- Potential Antitumor Activity of SIM-89 in Non-Small Cell Lung Cancer Cells
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Pei J, Chu T, Shao M, Teng J, Sha H, Gu A, Li R, Qian J, Mao W, Li Y, Han B
- KMID: 2419116
- Yonsei Med J.
- 2017 May;58(3):581-591.
- doi: 10.3349/ymj.2017.58.3.581
PURPOSE: c-Met and its ligand, hepatocyte growth factor (HGF), play a critical role in oncogenesis and metastatic progression. The aim of this study was to identify inhibited enzymogram and to... -
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- Cyclized Oligopeptide Targeting LRP5/6-DKK1 Interaction Reduces the Growth of Tumor Burden in a Multiple Myeloma Mouse Model
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Park BM, Kim EJ, Nam HJ, Zhang D, Bae CH, Kang M, Kim H, Lee W, Bogen B, Lim SK
- KMID: 2419106
- Yonsei Med J.
- 2017 May;58(3):505-513.
- doi: 10.3349/ymj.2017.58.3.505
PURPOSE: Dickkopf 1 (DKK1) has been extensively investigated in mouse models of multiple myeloma, which results in osteolytic bone lesions. Elevated DKK1 levels in bone marrow plasma and serum inhibit... -
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- Inhibition of autophagy protein LC3A as a therapeutic target in ovarian clear cell carcinomas
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Miyamoto M, Takano M, Aoyama T, Soyama H, Yoshikawa , Tsuda H, Furuya K
- KMID: 2413444
- J Gynecol Oncol.
- 2017 May;28(3):e33.
- doi: 10.3802/jgo.2017.28.e33
OBJECTIVE: Ovarian clear cell carcinoma (CCC) is one of histological subtypes showing poor prognosis due to chemoresistance. The association of autophagy-related proteins and clinical implementation in CCC has not been... -
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- Comparative Effects of Non-Thermal Atmospheric Pressure Plasma on Migration and Invasion in Oral Squamous Cell Cancer, by Gas Type
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Kang SU, Seo SJ, Kim YS, Shin YS, Koh YW, Lee CM, Yang SS, Lee JS, Moon E, Kang H, Ryeo JB, Lee Y, Kim CH
- KMID: 2427114
- Yonsei Med J.
- 2017 Mar;58(2):272-281.
- doi: 10.3349/ymj.2017.58.2.272
PURPOSE: The fourth state of matter, plasma is known as an ionized gas with electrons, radicals and ions. The use of non-thermal plasma (NTP) in cancer research became possible because... -
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- Stage-specific embryonic antigen: determining expression in canine glioblastoma, melanoma, and mammary cancer cells
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Lin W, Modiano JF, Ito D
- KMID: 2412594
- J Vet Sci.
- 2017 Mar;18(1):101-104.
- doi: 10.4142/jvs.2017.18.1.101
The expression of stage-specific embryonic antigens (SSEAs) was determined in several types of canine cancer cells. Flow cytometry showed SSEA-1 expression in glioblastoma, melanoma, and mammary cancer cells, although none... -
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- Establishment of Hepatocellular Cancer Induced Pluripotent Stem Cells Using a Reprogramming Technique
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Kim HJ, Jeong J, Park S, Jin YW, Lee SS, Lee SB, Choi D
- KMID: 2412193
- Gut Liver.
- 2017 Mar;11(2):261-269.
- doi: 10.5009/gnl15389
BACKGROUND/AIMS: Cancer is known to be a disease by many factors. However, specific results of reprogramming by pluripotency-related transcription factors remain to be scarcely reported. Here, we verified potential effects... -
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- Overexpression of miR-191 Predicts Poor Prognosis and Promotes Proliferation and Invasion in Esophageal Squamous Cell Carcinoma
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Gao X, Xie Z, Wang Z, Cheng K, Liang K, Song Z
- KMID: 2418891
- Yonsei Med J.
- 2017 Nov;58(6):1101-1110.
- doi: 10.3349/ymj.2017.58.6.1101
PURPOSE: Accumulating evidence has shown that dysregulation of microRNA-191 (miR-191) is closely associated with tumorigenesis and progression in a wide range of cancers. This study aimed to explore the potential... -
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- The Effectiveness of Ferritin as a Contrast Agent for Cell Tracking MRI in Mouse Cancer Models
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Lee CW, Choi SI, Lee SJ, Oh YT, Park G, Park NY, Yoon KA, Kim S, Kim D, Kim YH, Suh JS
- KMID: 2374188
- Yonsei Med J.
- 2017 Jan;58(1):51-58.
- doi: 10.3349/ymj.2017.58.1.51
PURPOSE: We aimed to investigate the effectiveness of ferritin as a contrast agent and a potential reporter gene for tracking tumor cells or macrophages in mouse cancer models. MATERIALS AND METHODS:... -
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- Aberrant Hypomethylation of Solute Carrier Family 6 Member 12 Promoter Induces Metastasis of Ovarian Cancer
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Sung HY, Yang SD, Park AK, Ju W, Ahn JH
- KMID: 2374185
- Yonsei Med J.
- 2017 Jan;58(1):27-34.
- doi: 10.3349/ymj.2017.58.1.27
PURPOSE: Ovarian cancer (OC) is the most fatal of gynecological malignancies with a high rate of recurrence. We aimed to evaluate the expression of solute carrier family 6, member 12... -
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- EGF Induced RET Inhibitor Resistance in CCDC6-RET Lung Cancer Cells
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Chang H, Sung JH, Moon SU, Kim HS, Kim JW, Lee JS
- KMID: 2374183
- Yonsei Med J.
- 2017 Jan;58(1):9-18.
- doi: 10.3349/ymj.2017.58.1.9
PURPOSE: Rearrangement of the proto-oncogene rearranged during transfection (RET) has been newly identified potential driver mutation in lung adenocarcinoma. Clinically available tyrosine kinase inhibitors (TKIs) target RET kinase activity, which... -
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