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Human Skin Safety Test of Green Tea Cell Extracts in Condition of Allergic Contact Dermatitis

Kim HK, Choi SY, Chang HK, Baek SY, Chung JO, Rha CS, Kim BJ, Kim MN

  • KMID: 1432248
  • Toxicol Res.
  • 2012 Jun;28(2):113-116.
Various kinds of positive effects of green tea extracts had been studied for long time which included anti-inflammation, anti-aging, and cardiometabolic effects. Although topical steroid and non-steroidal calcineurin inhibitors may...
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The Frequency of Serum IgA autoantibody in Patients with Pemphigus

Jun JH, Chang SY, Lee CW

  • KMID: 2086299
  • Korean J Dermatol.
  • 2000 Jan;38(1):67-71.
BACKGROUND: Pemphigus is an autoimmune bullous disease with circulating desmosomal autoantibodies of IgG. In direct IF studies with perilesional tissue, IgA or IgM antibodies can be seen in addition to...
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Inducible Activation of NFkB on Cultured Normal Human Urothelial Cells

Shin MS, Appell R

  • KMID: 2289961
  • Korean J Urol.
  • 1999 Mar;40(3):303-307.
PURPOSE: We investigated the inducible response of transcription factor Nuclear Factor Kappa B(NFkB) in response to lipopolysaccharide(LPS), interferons(INFs), and tumor necrosis factor(TNF) on the normal urothelial cells derived from the...
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Growth Suppression of Ovarian Cancer Cells by Interferon-gama

Park JS, Kim EJ, Park TC, Kim EJ, Kim J, Lee JM, Namkoong S, Um SJ

  • KMID: 2166235
  • Cancer Res Treat.
  • 2001 Jun;33(3):236-242.
PURPOSE: Growth regulation of cancer cells very frequently involves tumor suppressor gene p53, Rb and cell cycle regulator, however the molecular biologic mechanisms of growth regulation in ovarian carcinoma cells...
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Inducible Activation of NFkappaB in Lour Grade and High Grade Transitional Carcinoma Cell Lines

Shin MS, Rackley R, Appell R

  • KMID: 2290247
  • Korean J Urol.
  • 1998 Apr;39(4):311-315.
PURPOSE: While the exact inflammatory and immunological mechanisms involved in the induction of immunotherapy for superficial bladder carcinoma are mostly unknown, many of these mechanisms are mediated through the...
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Ghrelin Inhibits Oligodendrocyte Cell Death by Attenuating Microglial Activation

Lee JY, Yune TY

BACKGROUND: Recently, we reported the antiapoptotic effect of ghrelin in spinal cord injury-induced apoptotic cell death of oligodendrocytes. However, how ghrelin inhibits oligodendrocytes apoptosis, is still unknown. Therefore, in the...
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Differential Expression of Peroxiredoxin Isotypes in Cultured Cells from Human and Rat Skin

Ahn EY, Lee JB, Won YH, Lee SC

  • KMID: 2230317
  • Korean J Dermatol.
  • 2000 Nov;38(11):1481-1487.
BACKGROUND: Peroxiredoxin(Prx) is a novel peroxidase family to remove hydrogen peroxide using thioredoxin system, which is consisted of thioredoxin, thioredoxin reductase and NADPH. Several enzymatic antioxidants, such as superoxide dismutase,...
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Antiproliferative and Apoptotic Effects of Zinc-Citrate Compound (CIZAR(R)) on Human Epithelial Ovarian Cancer Cell (OVCAR3)

Lee YS, Kim JD, Park LO, Bae SN

  • KMID: 2272841
  • Korean J Obstet Gynecol.
  • 2006 Jul;49(7):1427-1436.
OBJECTIVE: Human seminal plasma has diverse biological activities including cytotoxic effect. It contains high concentrations of zinc and citric acid. Zinc inhibits several carcinoma cell growths through induction of cell...
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Production of Antibody against Helicobacter pylori HP0231

Lee J, Lee SY, Lee JH

BACKGROUND: Stool antigen detection kits for diagnosis of infection of Helicobacter pylori have been widely used for their convenience, but are mostly imported. Since Helicobacter pylori strains show a distinctive...
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Rate of Synthesis and Degradation of Lysozyme Protein by Retinoic Acid in Normal Human Airway Epithelial Cells

Yoon JH, Hong SS, Hong JP, Lee GY, Park IY

  • KMID: 2115398
  • Korean J Otolaryngol-Head Neck Surg.
  • 1999 Aug;42(8):981-984.
BACKGROUND AND OBJECTIVES: We considered two possible mechanisms that might be responsible for the increased accumulation of lysozyme in retinoic acid (RA)-deficient cultures, either increased lysozyme synthesis or decreased lysozyme...
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Activation of Stat Protein in Synovial Cell in Rheumatoid Arthritis

Shim SC, Lee IH, Jung JH, Kim TH, Jun JB, Song KW, Bae SC, Yoo DH, Kim SY

  • KMID: 2202485
  • J Korean Rheum Assoc.
  • 2000 Mar;7(1):43-52.
OBJECTIVE: To characterize Stat activity in synovial tissue in rheumatoid arthritis (RA) in order to see if Stat molecule contributes to the pathogenesis of RA by regulatory expression of...
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Change of the Antigenecity of Human Papillomavirus Type 16 E7 Oncoprotein according to Phosphorylation

Park NH, Kee SH, Noh JW, Kim JW, Song YS, Kang SB, Lee HP

  • KMID: 2329122
  • J Korean Cancer Assoc.
  • 1998 Apr;30(2):313-320.
PURPOSE: It was suggested that immunogenic region of E7 proteins of human papillo- mavirus (HPV) type 16 encompass casein kinase (CK) II phosphorylation site and the resulting negative charge may...
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Growth Inhibition of Hepatocellular Carcinoma Huh7 Cells by Lactobacillus casei Extract

Han DJ, Kim JB, Park SY, Yang MG, Kim H

PURPOSE: Lactobacillus casei (L. casei) is known to exert anti-proliferation effects on many types of cancer cells. However, the effect of L. casei on liver cancer has not been reported....
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A Prospective Multi-center Trial of Escherichia coli Extract for the Prophylactic Treatment of Patients with Chronically Recurrent Cystitis

Kim KS, Kim JY, Jeong IG, Paick JS, Son H, Lim DJ, Shim HB, Park WH, Jung HC, Choo MS

We have assessed the efficacy and safety of Escherichia coli extract (ECE; Uro-Vaxom(R)) which contains active immunostimulating fractions, in the prophylactic treatment of chronically recurrent cystitis. Forty-two patients with more...
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Improved immunodetection of human papillomavirus E7

Jeon JH, Cho SY, Kim CW, Shin DM, Kwon JC, Choi KH, Kim IG

  • KMID: 1121105
  • Exp Mol Med.
  • 2002 Dec;34(6):496-499.
Human papillomavirus E7 (HPV E7) is a viral oncoprotein that plays an important role in cervical carcinogenesis through binding with retinoblastoma protein (Rb). Inactivation of Rb by E7 is...
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Shear stress stimulates phosphorylation of protein kinase A substrate proteins including endothelial nitric oxide synthase in endothelial cells

Boo YC

  • KMID: 1105278
  • Exp Mol Med.
  • 2006 Feb;38(1):63-71.
Fluid shear stress plays a critical role in vascular health and disease. While protein kinase A (PKA) has been implicated in shear-stimulated signaling events in endothelial cells, it remains unclear...
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Grifola frondosa water extract alleviates intestinal inflammation by suppressing TNF-alpha production and its signaling

Lee JS, Park SY, Thapa D, Choi MK, Chung IM, Park YJ, Yong CS, Choi HG, Kim JA

TNF-alpha is a major cytokine involved in inflammatory bowel disease (IBD). In this study, water extract of Grifola frondosa (GFW) was evaluated for its protective effects against colon inflammation through...
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