- Differential Expression of TGF-beta Isoforms During Differentiation of HaCaT Human Keratinocyte Cells: Implication for the Separate Role in Epidermal Differentiation
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Cho HR, Hong SB, Kim YI, Lee JW, Kim NI
- KMID: 1778568
- J Korean Med Sci.
- 2004 Dec;19(6):853-858.
- doi: 10.3346/jkms.2004.19.6.853
The three mammalian isoforms of transforming growth factor-beta (TGF-beta1, beta2, beta3) are potent regulators of cell growth, differentiation, and extracellular matrix deposition. To study their role in skin differentiation, we... -
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- Pim-1: A serine/threonine kinase with a role in cell survival, proliferation, differentiation and tumorigenesis
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Wang Z, Bhattacharya N, Weaver M, Petersen K, Meyer M, Gapter L, Magnuson N
- KMID: 1119212
- J Vet Sci.
- 2001 Dec;2(3):167-179.
Pim-1 belongs to a family of serine/threonine protein kinases that are highly conserved through evolution in multicellular organisms. Originally identified from moloney murine leukemia virus (MuLV)-induced T-cell lymphomas in mice,... -
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- Effect of donor age on the proliferation and multipotency of canine adipose-derived mesenchymal stem cells
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Lee J, Lee KS, Kim CL, Byeon JS, Gu NY, Cho IS, Cha SH
- KMID: 2412566
- J Vet Sci.
- 2017 Jun;18(2):141-148.
- doi: 10.4142/jvs.2017.18.2.141
Research into adipose tissue-derived mesenchymal stem cells (AD-MSCs) has demonstrated the feasibility of their use in clinical applications due to their ease of isolation and abundance in adipose tissue. We... -
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- Vascular differentiation of multipotent spermatogonial stem cells derived from neonatal mouse testis
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Im JE, Song SH, Kim JY, Kim KL, Baek SH, Lee DR, Suh W
- KMID: 1365907
- Exp Mol Med.
- 2012 Apr;44(4):303-309.
- doi: 10.3858/emm.2012.44.4.034
We previously reported the successful establishment of embryonic stem cell (ESC)-like multipotent spermatogonial stem cells (mSSCs) from neonatal mouse testis. Here, we examined the ability of mSSCs to differentiate into... -
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- Sertoli cell proliferation during the post hatching period in domestic fowl
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Bozkurt HH, Akta A, Ulkay MB, Firat UB
- KMID: 1090794
- J Vet Sci.
- 2007 Sep;8(3):219-222.
- doi: 10.4142/jvs.2007.8.3.219
There has been no study aimed at directly determiningof the periods of Sertoli cell proliferation in birds evendomestic fowl. The aims of this study were to observe thecessation of post-hatching... -
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- In vitro model of atherosclerosis using coculture of arterial wall cells and macrophage
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Wada Y, Sugiyama A, Kohro T, Kobayashi , Takeya M, Naito M, Kodama T
- KMID: 1114562
- Yonsei Med J.
- 2000 Dec;41(6):740-755.
- doi: 10.3349/ymj.2000.41.6.740
In order to determine the precise mechanism of the interactions between different types of cells, which are common phenomena in tissues and organs, the importance of coculture techniques are becoming... -
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- PKC alpha induces differentiation through ERK1/2 phosphorylation in mouse keratinocytes
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Seo HR, Kwan YW, Cho CK, Bae S, Lee SJ, Soh JW, Chung HY, Lee YS
- KMID: 1094073
- Exp Mol Med.
- 2004 Aug;36(4):292-299.
Epidermal keratinocyte differentiation is a tightly regulated stepwise process that requires protein kinase C (PKC) activation. Studies on cultured mouse keraitnocytes induced to differentiate with Ca2+ have indirectly implicated the... -
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- Neurorestoration Induced by Mesenchymal Stem Cells: Potential Therapeutic Mechanisms for Clinical Trials
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Seo JH, Cho SR
- KMID: 1414244
- Yonsei Med J.
- 2012 Nov;53(6):1059-1067.
- doi: 10.3349/ymj.2012.53.6.1059
Stem cells are emerging as therapeutic candidates in a variety of diseases because of their multipotent capacities. Among these, mesenchymal stem cells (MSCs) derived from bone marrow, umbilical cord blood... -
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- Extracellular ATP is generated by ATP synthase complex in adipocyte lipid rafts
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Kim BW, Choo HJ, Lee JW, Kim JH, Ko YG
- KMID: 1123769
- Exp Mol Med.
- 2004 Oct;36(5):476-485.
Mitochondrial biogenesis is known to accompany adipogenesis to complement ATP and acetyl-CoA required for lipogenesis. Here, we demonstrated that mitochondrial proteins such as ATP synthase alpha and beta, and cytochrome... -
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- Rapid Isolation of Adipose Tissue-Derived Stem Cells by the Storage of Lipoaspirates
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Eom YW, Lee JE, Yang MS, Jang IK, Kim HE, Lee DH, Kim YJ, Park WJ, Kong JH, Shim KY, Lee JI, Kim HS
- KMID: 1058822
- Yonsei Med J.
- 2011 Nov;52(6):999-1007.
- doi: 10.3349/ymj.2011.52.6.999
PURPOSE: This study examined a rapid isolation method decreasing the time and cost of the clinical application of adipose tissue-derived stem cells (ASCs). MATERIALS AND METHODS: Aliquots (10 g) of the... -
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- Tissue engineering of heart valves by recellularization of glutaraldehyde-fixed porcine valves using bone marrow-derived cells
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Kim SS, Lim SH, Cho SW, Gwak SJ, Hong YS, Chang BC, Park MH, Song KW, Choi CY, Kim BS
- KMID: 1094153
- Exp Mol Med.
- 2006 Jun;38(3):273-283.
To increase the biocompatibility and durability of glutaraldehyde (GA)-fixed valves, a biological coating with viable endothelial cells (ECs) has been proposed. However, stable EC layers have not been formed successfully... -
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- A comparative study on aberrations of chromosome 17 and proliferating cell fraction in lung cancer
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Lee KJ, Lee MS, Kim JO, Kim SY
- KMID: 2157511
- J Korean Med Sci.
- 1993 Aug;8(4):271-280.
- doi: 10.3346/jkms.1993.8.4.271
To better understand the relationship between specific chromosome changes found in human lung tumors and their phenotypic consequences a the tissue level, an in situ hybridization (ISH) procedure of chromosome... -
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- Mesenchymal stem cells promote proliferation of endogenous neural stem cells and survival of newborn cells in a rat stroke model
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Yoo SW, Kim SS, Lee SY, Lee HS, Kim HS, Lee YD, Suh-Kim H
- KMID: 1094118
- Exp Mol Med.
- 2008 Aug;40(4):387-397.
- doi: 10.3858/emm.2008.40.4.387
Mesenchymal stem cells (MSCs) secrete bioactive factors that exert diverse responses in vivo. In the present study, we explored mechanism how MSCs may lead to higher functional recovery in the... -
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- Basic fibroblast growth factor-induced translocation of p21-activated kinase to the membrane is independent of phospholipase C-gamma1 in the differentiation of PC12 cells
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Shin KS, Shin EY, Lee CS, Quan SH, Woo KN, Soung NK, Kwak SJ, Kim SR, Kim EG
- KMID: 1081468
- Exp Mol Med.
- 2002 May;34(2):172-176.
p21-activated kinase (PAK) targeting to the plasma membrane is essential for PC12 cell neurite outgrowth. Phospholipase C-gamma1 (PLC-gamma1) can mediate the PAK translocation in response to growth factors, since PLC-gamma1... -
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- High expression of epidermal growth factor-like domain 7 is correlated with poor differentiation and poor prognosis in patients with epithelial ovarian cancer
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Oh J, Park SH, Lee TS, Oh HK, Choi JH, Choi YS
- KMID: 2130123
- J Gynecol Oncol.
- 2014 Oct;25(4):334-341.
- doi: 10.3802/jgo.2014.25.4.334
OBJECTIVE: The purpose of this study was to evaluate the expression of epidermal growth factor-like domain 7 (EGFL7) in epithelial ovarian cancer, and to assess its relevance to clinicopathological characteristics... -
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- Therapeutic Effects of Mesenchymal Stem Cells for Patients with Chronic Liver Diseases: Systematic Review and Meta-analysis
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Kim G, Eom YW, Baik SK, Shin Y, Lim YL, Kim MY, Kwon SO, Chang SJ
- KMID: 2344172
- J Korean Med Sci.
- 2015 Oct;30(10):1405-1415.
- doi: 10.3346/jkms.2015.30.10.1405
Based on their ability to differentiate into multiple cell types including hepatocytes, the transplantation of mesenchymal stem cells (MSCs) has been suggested as an effective therapy for chronic liver diseases.... -
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