- Increased p190RhoGEF expression in activated B cells correlates with the induction of the plasma cell differentiation
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Ha YJ, Jeong JH, Park Y, Lee JR
- KMID: 1120132
- Exp Mol Med.
- 2012 Feb;44(2):138-148.
- doi: 10.3858/emm.2012.44.2.009
Previously, we demonstrated that the p190 Rho guanine nucleotide exchange factor (p190RhoGEF) was induced following CD40 stimulation of B cells. In this study, we examined whether p190RhoGEF and a downstream... -
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- Overexpression of SOX9 in mouse embryonic stem cells directs the immediate chondrogenic commitment
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Kim JH, Do HJ, Yang HM, Oh JH, Choi SJ, Kim DK, Cha KY, Chung HM
- KMID: 1093460
- Exp Mol Med.
- 2005 Aug;37(4):261-268.
Mouse embryonic stem (mES) cells are capable of undergoing chondrogenesis in vitro. To enhance this process, the human SOX9 (hSOX9) cDNA was delivered into mES cells and the clones overexpressing... -
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- Expression patterns of beta ig-h3 in chondrocyte differentiation during endochondral ossification
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Han MS, Kim JE, Shin HI, Kim IS
- KMID: 1094125
- Exp Mol Med.
- 2008 Aug;40(4):453-460.
- doi: 10.3858/emm.2008.40.4.453
beta ig-h3 is a TGF-beta-induced extracellular matrix protein which is expressed in many tissues including bones and cartilages. In previous reports, we showed that beta ig-h3 mediates cell adhesion and... -
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- Regulation of osteogenic differentiation of human adipose-derived stem cells by controlling electromagnetic field conditions
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Kang KS, Hong JM, Kang JA, Rhie JW, Jeong YH, Cho DW
- KMID: 2154225
- Exp Mol Med.
- 2013 Jan;45(1):e6.
Many studies have reported that an electromagnetic field can promote osteogenic differentiation of mesenchymal stem cells. However, experimental results have differed depending on the experimental and environmental conditions. Optimization of... -
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- A Gene and Neural Stem Cell Therapy Platform Based on Neuronal Cell Type-Inducible Gene Overexpression
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Oh J, You Y, Yun Y, Lee HL, Yoon DH, Lee M, Ha Y
- KMID: 2366346
- Yonsei Med J.
- 2015 Jul;56(4):1036-1043.
- doi: 10.3349/ymj.2015.56.4.1036
PURPOSE: Spinal cord injury (SCI) is associated with permanent neurological damage, and treatment thereof with a single modality often does not provide sufficient therapeutic outcomes. Therefore, a strategy that combines... -
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- Cyclooxygenase-2 Expression Is Related to the Epithelial-to-Mesenchymal Transition in Human Colon Cancers
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Jang TJ, Jeon KH, Jung KH
- KMID: 1777097
- Yonsei Med J.
- 2009 Dec;50(6):818-824.
- doi: 10.3349/ymj.2009.50.6.818
PURPOSE: Down-regulation of E-cadherin is a hallmark of the epithelial-to-mesenchymal transition (EMT). EMT progression in cancer cells is associated with the loss of certain epithelial markers and the acquisition of... -
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- Overexpression of bone morphogenetic protein 4 in STO fibroblast feeder cells represses the proliferation of mouse embryonic stem cells in vitro
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Kim GH, Lee GR, Choi HI, Park NH, Chung HT, Han IS
- KMID: 1397450
- Exp Mol Med.
- 2012 Jul;44(7):457-463.
Embryonic stem cells (ESCs) can be propagated in vitro on feeder layers of mouse STO fibroblast cells. The STO cells secrete several cytokines that are essential for ESCs to maintain... -
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- Analyses of the TCR repertoire of MHC class II-restricted innate CD4+ T cells
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Kang BH, Min HS, Lee YJ, Choi B, Kim EJ, Lee J, Kim JR, Cho KH, Kim TJ, Jung KC, Park SH
- KMID: 2155419
- Exp Mol Med.
- 2015 Mar;47(3):e154.
- doi: 10.1038/emm.2015.7
Analysis of the T-cell receptor (TCR) repertoire of innate CD4+ T cells selected by major histocompatibility complex (MHC) class II-dependent thymocyte-thymocyte (T-T) interaction (T-T CD4+ T cells) is essential for... -
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- Amplification of c-erbB-2 proto-oncogene in cancer foci, adjacent normal, metastatic and normal tissues of human primary gastric adenocarcinomas
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Kim JS, Choi CW, Kim BS, Shin SW, Kim YH, Mok YJ, Kim JS, Koo BH
- KMID: 1081052
- J Korean Med Sci.
- 1997 Aug;12(4):311-315.
- doi: 10.3346/jkms.1997.12.4.311
Genetic damages are frequently found in both tumor and normal cells at carcinogen exposed areas in the patients with upper aerodigestive tract cancer. These phenomena are explained by the... -
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- Obesity aggravates the joint inflammation in a collagen-induced arthritis model through deviation to Th17 differentiation
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Jhun JY, Yoon BY, Park MK, Oh HJ, Byun JK, Lee SY, Min JK, Park SH, Kim HY, Cho ML
- KMID: 1397446
- Exp Mol Med.
- 2012 Jul;44(7):424-431.
White fat cells secrete adipokines that induce inflammation and obesity has been reported to be characterized by high serum levels of inflammatory cytokines such as IL-6 and TNF-alpha. Rheumatoid arthritis... -
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