- Effect of preoperative administration of celecoxib on postoperative pain after laparoscopic cholecystectomy
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Kim DY, An YM, Moon JP, Choi JG
- KMID: 2236502
- Korean J Anesthesiol.
- 2009 Sep;57(3):327-330.
- doi: 10.4097/kjae.2009.57.3.327
BACKGROUND: For laparoscopic cholecystectomy, pain is most frequent complaint and the most common cause of delayed discharge. The aim of this study was to determine the effect of preoperative administration... -
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- A Case of Erythema Multiforme Probably Induced by Celecoxib
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Na JI, Lee DH, Suh DH
- KMID: 2248915
- Korean J Dermatol.
- 2006 Dec;44(12):1467-1468.
Celecoxib (Celebrex(R)) is a nonsteroidal anti-inflammatory drug (NSAID) which inhibits cycloxygenase (COX)-2 selectively. It is widely used in osteoarthritis and rheumatoid arthritis patients because it causes less gastrointestinal injury than... -
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- A Case of Drug Eruption Induced by Celecoxib
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Ko JY, Ro YS, Kim JH
- KMID: 2303069
- Korean J Dermatol.
- 2002 Nov;40(11):1423-1425.
A drug eruption is any adverse skin reaction caused by a drug used in a normal dose. Celecoxib(Celebrex(R)), a cyclooxygenase(COX) 2 inhibitor, is a new generation non-steroidal anti- inflammatory drug,... -
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- Cardiovascular Safety of Celecoxib on Top of Dual Antiplatelet Therapy
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Hong BK
- KMID: 2225172
- Korean Circ J.
- 2010 Jul;40(7):306-307.
- doi: 10.4070/kcj.2010.40.7.306
No abstract available. -
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- Effect of Celecoxib, a Cyclooxygenase-2-specific Inhibitor, has no Effect on Chronically Maintained Neuropathic Pain in Rats
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Park ES, Kim HJ, Lee MJ, Lee JY, Shin TJ, Seo KS, Yum KW
- KMID: 2345124
- J Korean Dent Soc Anesthesiol.
- 2008 Jun;8(1):29-34.
- doi: 10.17245/jkdsa.2008.8.1.29
No abstract available in English. -
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- Celecoxib induces cell death on non-small cell lung cancer cells through endoplasmic reticulum stress
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Kim B, Kim J, Kim YS
- KMID: 2399898
- Anat Cell Biol.
- 2017 Dec;50(4):293-300.
- doi: 10.5115/acb.2017.50.4.293
Cyclooxygenase-2 (COX-2) is an enzyme induced by various proinflammatory and mitogenic stimuli. Celecoxib is a selective inhibitor of COX-2 that have been shown to affect cell growth and apoptosis. Lung... -
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- Change of the Invasiveness with Selective Cox-2 Inhibition in an Oral Squamous Cell Carcinoma Cell Line, KB; Preliminary in Vitro Study
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Lee EJ, Kim MJ, Myoung H
- KMID: 2190305
- J Korean Assoc Oral Maxillofac Surg.
- 2007 Apr;33(2):103-108.
Cyclooxygenase-2 (Cox-2) is known as one of the critical factor in carcinomas of various organs. However, the importance of Cox-2 in oral squamous cell carcinoma has not been fully described... -
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- Inhibitory Effect of IFN-beta, on the Antitumor Activity of Celecoxib in U87 Glioma Model
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Kim EK, Chung DS, Shin HJ, Hong YK
- KMID: 2190207
- J Korean Neurosurg Soc.
- 2009 Dec;46(6):552-557.
- doi: 10.3340/jkns.2009.46.6.552
OBJECTIVE: Interferon-beta, (IFN-beta) has been used in the treatment of cancers. Inhibition of the enzyme cyclooxygenase (COX) with celecoxib had a significantly suppressive effect on tumor growth, angiogenesis, and metastasis... -
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- A Case of Erythema Multiforme Induced by Celecoxib
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- KMID: 2234616
- Korean J Asthma Allergy Clin Immunol.
- 2009 Jun;29(2):138-141.
Celecoxib (Celebrex(R)) is a nonsteroidal anti-inflammatory drug (NSAID) which selectively inhibits cyclooxygenase (COX)-2. Celecoxib rarely induces serious cutaneous adverse reaction such as erythema multiforme, Steven-Johnson syndrome and toxic epidermal necrosis.... -
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- Effect of Cyclooxygenase-2 Specific Inhibitor (SC-58635) on the Production of Nitric Oxide and Prostaglandin E2 in Lipopolysaccharide-stimulated Macrophage Cells
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Hong SJ, Yang HI, Yoon HJ, Lee MS, Kang HJ, Kim WU, Lee SH, Cho CS, Kim HY
- KMID: 2167973
- Immune Netw.
- 2003 Mar;3(1):69-77.
- doi: 10.4110/in.2003.3.1.69
BACKGROUND: Celecoxib, a COX-2 specific inhibitor, has recently been used for the treatment of rheumatoid arthritis. However, the molecular and cellular mechanisms of celecoxib against RA inflammation remain to be... -
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- Celecoxib Does Not Attenuate the Antiplatelet Effects of Aspirin and Clopidogrel in Healthy Volunteers
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Lee W, Suh JW, Yang HM, Kwon DA, Cho HJ, Kang HJ, Kim HS, Oh BH
- KMID: 2225175
- Korean Circ J.
- 2010 Jul;40(7):321-327.
- doi: 10.4070/kcj.2010.40.7.321
BACKGROUND AND OBJECTIVES: The prevalence of arthritis, which is often treated with celecoxib, is high in patients with coronary artery disease. Furthermore, celecoxib has been reported to reduce restenosis after... -
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- The Enhancement of Radiosensitivity by Celecoxib, Selective Cyclooxygenase-2 Inhibitor, on Human Cancer Cells Expressing Differential Levels of Cyclooxygenase-2
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Pyo H, Shin YK, Kim HS, Seong J, Suh CO, Kim GE
- KMID: 2198628
- J Korean Soc Ther Radiol Oncol.
- 2003 Sep;21(3):216-221.
PURPOSE: To investigate the modulation of radiosensitivity by celecoxib, a selective cyclooxygenase-2 (COX-2) inhibitor, on cancer cells over- and under-expressing COX-2. MATERIALS AND METHODS: A clonogenic radiation survival analysis was performed... -
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- Familial Adenomatous Polyposis Improved by COX-2 Inhibitor in a Child
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Oh KW, Kim SY, Lee HS, Lee MH, Choe BH
- KMID: 2207110
- J Korean Pediatr Soc.
- 2002 Dec;45(12):1591-1595.
Familial adenomatous polyposis(FAP) is an autosomal dominant disease characterized by numerous adenomas in the colorectum. Patients with FAP are always at risk of malignant transformation, so that colectomy is unavoidable.... -
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- Synergistic Effect of COX-2 Inhibitor on Paclitaxel-Induced Apoptosis in the Human Ovarian Cancer Cell Line OVCAR-3
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Kim HJ, Yim GW, Nam EJ, Kim YT
- KMID: 2167661
- Cancer Res Treat.
- 2014 Jan;46(1):81-92.
PURPOSE: Celecoxib, a highly selective cyclooxygenase-2 inhibitor, regulates apoptosis of several types of human cancer cells. The purpose of this study was to investigate whether celecoxib in combination with paclitaxel... -
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- A Case of Celecoxib Induced Acute Generalized Exanthematous Pustulosis
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Shin HT, Park SW, Lee KT, Park HY, Park JH, Lee DY, Lee JH, Yang JM, Lee ES
- KMID: 2171877
- Ann Dermatol.
- 2011 Dec;23(Suppl 3):S380-S382.
- doi: 10.5021/ad.2011.23.S3.S380
Acute generalized exanthematous pustulosis (AGEP) is manifested by rapid development of many sterile, nonfollicular pustules on a background of edematous erythema. More than 90 percent of AGEP are induced by... -
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- COX-2 inhibitor induced apoptosis in oral squamous cell carcinoma cell line through AKT pathway
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Seo YH, Han SJ, Lee JH
- KMID: 2184413
- J Korean Assoc Maxillofac Plast Reconstr Surg.
- 2008 Jan;30(1):30-40.
The objectives of this study was to check up the effect of celecoxib, COX-2 inhibitor, on the pathogenesis of oral squamous cell carcinoma. After mefenamic acid, aspirin and celecoxib, COX-2... -
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- The Effects of Celecoxib on Wound Healing in Murine Wound Models
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Roh JL, Sung MW, Kim KH, Park SW, Oh SJ, Jin YD, Rha KS, Park CI
- KMID: 2276253
- Korean J Otolaryngol-Head Neck Surg.
- 2004 Oct;47(10):1020-1025.
BACKGROUND AND OBJECTIVES: Celecoxib has suppressive effects on the growth, angiogenesis, metastasis of solid tumors including head and neck squamous cell carcinoma. Recent report suggests that celecoxib can also be... -
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- Multicenter Study in Efficacy and Safety of Celecoxib in Patients with Rheumatoid Arthritis and Osteoarthritis
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Seong SS, Park YB, Uhm WS, Lee J, Ji JD, Bae SC, Celecoxib PMS Investigators
- KMID: 2202231
- J Korean Rheum Assoc.
- 2006 Sep;13(3):209-217.
OBJECTIVE: The aim of this study was to define the efficacy and safety of celecoxib in Korean patients with rheumatoid arthritis and osteoarthritis. In addition, the impact of gastrointestinal symptom... -
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- Apoptotic Effect of the Cyclooxygenase-2 Inhibitor Celecoxib on Human Breast Cancer MDA-MB 468 Cells
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Cha Y, Ko HS, Kim H, Kim JR, Kim JH
- KMID: 2286649
- J Breast Cancer.
- 2006 Sep;9(3):193-199.
- doi: 10.4048/jbc.2006.9.3.193
Purpose: Cyclooxygenase (COX) is an enzyme that catalyzes the conversion of arachidonic acid to prostaglandins. The inducible form, COX-2, is induced by such proinflammatory and mitogenic stimuli as cytokines and... -
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- Inhibition of Phorbol Ester-induced Mouse Skin Tumor Promotion and COX-2 Expression by Celecoxib: C/EBP as a Potential Molecular Target
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Chun KS, Kundu JK, Park KK, Chung WY, Surh YJ
- KMID: 2166060
- Cancer Res Treat.
- 2006 Jun;38(3):152-158.
PURPOSE: Inflammation acts as a driving force for the development of cancer. Multiple lines of evidence suggest that nonsteroidal anti-inflammatory drugs, especially those that specifically target cyclooxygenase-2 (COX-2), are effective... -
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