- Significance of the Expression of Cathepsins B, H, & L in Colonic Epithelial Neoplasms
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Sim JY, Lee MJ, Kee KH
- KMID: 1472618
- Korean J Pathol.
- 2009 Oct;43(5):408-412.
- doi: 10.4132/KoreanJPathol.2009.43.5.408
BACKGROUND: Cathepsin is associated with tumorigenesis, tumor invasion and metastasis through its ability to induce degradation of extracellular matrix components. METHODS: To investigate the correlation between cathepsin expression and tumor progression,... -
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- Potential role(s) of cysteine cathepsins in cancer progression and metastasis
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Lee HR, Choi KC
- KMID: 2055088
- J Biomed Res.
- 2013 Mar;14(1):1-7.
Cancer is the result of damage to the genetic system, i.e., dysfunction of the DNA repair system, resulting in dysregulated expression of various molecules, leading to cancer formation, migration, and... -
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- Resistance to Chemotherapy on Tumor Through Cathepsin B-dependent Activation of the NLRP3 Inflammasome
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Kwon EJ, Koh YS
- KMID: 2286278
- J Bacteriol Virol.
- 2013 Sep;43(3):233-234.
- doi: 10.4167/jbv.2013.43.3.233
Anticancer drugs kill tumor cells and increase host anti-tumor immunity. Interestingly, gemcitabin (Gem) and 5-fluorouracil (5-FU), widely used anticancer drugs, lead to IL-1beta secretion releasing cathepsin B which activates Nlrp3... -
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- Study on the Expression of E-cadherin and Cathepsin B in the Prostatic Carcinomas with the Evaluation of the Gleason Grade
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Sol MY, Lee JS, Chae HJ, Chung MK
- KMID: 2175340
- J Korean Cancer Assoc.
- 1998 Oct;30(5):980-989.
PURPOSE: The purpose of this study is to evaluate the expression of E-cadherin and cathepsin-B in prostatic carcinomas and correlate with the Gleason grades. MATERIALS AND METHODS: The expressions of... -
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- Expression of Cathepsin B mRNA and Protein in Eutopic and Ectopic Endometrial Tissues of Patients with Endometriosis
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Lee SJ, Kim CH, Lee YJ, Kim JS, Koo YH, Lee SR, Kim SH, Chae HD, Kang BM
- KMID: 2272875
- Korean J Obstet Gynecol.
- 2006 Aug;49(8):1712-1722.
OBJECTIVE: This study was performed to investigate the expression of cathepsin B mRNA and Protein in eutopic and ectopic endometrial tissues of patients with endometriosis and in normal endometrial tissues,... -
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- Membrane - bound Cathepsin B - like Protease Activity in Malignant Skin Tumors
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Lee MR, Park MS, Lee SC, Won YH, Kim YP, Chun IK
- KMID: 2085760
- Korean J Dermatol.
- 1994 Nov;32(6):971-976.
BACKGROUND: Malignant skin tumor cells derived from epidemal keratinocyte penetrate the basement membrane to proliferate in dermal interstitial strozirarnd invade surrounding tissue and finally metastasize to distant organs. In this... -
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- Inhibition of in vitro Human Bladder Cancer Cell Invasion by Proteinase Inhibitor
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Kim CS, Kim SW
- KMID: 2289259
- Korean J Urol.
- 1995 Dec;36(12):1291-1300.
The invasion of basement membrane is one of the most important steps for tumor dissemination. Invasive human bladder tumor cells have the ability to degrade basement membrane, especially laminin with... -
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- Interleukin-10 Down-Regulates Cathepsin B Expression in Fetal Rat Alveolar Type II Cells Exposed to Hyperoxia
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Lee HS, Kim CK
- KMID: 1503909
- Yonsei Med J.
- 2013 Mar;54(2):445-452.
- doi: 10.3349/ymj.2013.54.2.445
PURPOSE: Hyperoxia has the chief biological effect of cell death. We have previously reported that cathepsin B (CB) is related to fetal alveolar type II cell (FATIIC) death and pretreatment... -
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- Retinoic Acid Inhibition of Human Bladder Tumor Cell Invasion in Membrane Invasion Culture System
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Kim CS
- KMID: 2060548
- Korean J Urol.
- 1995 Jan;36(1):9-16.
During the development of invasive tumor, tumor cells penetrate the basement membrane and enter the underlying interstitial stroma to gain access to lymphatics and blood vessel for further dissemination. Invasion... -
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- Cathepsin B is activated as an executive protease in fetal rat alveolar type II cells exposed to hyperoxia
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Lee HS, Kim CK
- KMID: 1104392
- Exp Mol Med.
- 2011 Apr;43(4):223-229.
- doi: 10.3858/emm.2011.43.4.027
Alveolar type II cells are main target of hyperoxia-induced lung injury. The authors investigated whether lysosomal protease, cathepsin B (CB), is activated in fetal alveolar type II cells in the... -
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- Heat Shock Proteins and Autophagy in Rats with Cerulein-Induced Acute Pancreatitis
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Kim JN, Lee HS, Ryu SH, Kim YS, Moon JS, Kim CD, Chang IY, Yoon SP
- KMID: 2284244
- Gut Liver.
- 2011 Dec;5(4):513-520.
BACKGROUND/AIMS: Heat shock proteins (HSPs) protect rats from cerulein-induced acute pancreatitis (AP) by preventing the subcellular redistribution of cathepsin B and the activation of trypsinogen. Autophagy plays a critical role... -
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- Characterization of HC58cDNA, a putative cysteine protease from the parasite Haemonchus contortus
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Muleke CI, Ruofeng Y, Lixin X, Yanming S, Xiangrui L
- KMID: 1089909
- J Vet Sci.
- 2006 Sep;7(3):249-255.
- doi: 10.4142/jvs.2006.7.3.249
Because of the complexity of the cathepsin B-like (CBL) family, an information on the biological and biochemical characteristics of individual CBL genes is lacking. In this study, we investigated the... -
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