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Recent Updates on Narcolepsy and Hypersomnia

Hong S

Narcolepsy is a chronic neurological sleep disorder caused by hypocretin neuron loss, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and intrusions of aspects of rapid eye movement sleep in...
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Updates on structural neuroimaging of narcolepsy with cataplexy

Joo EY

Narcolepsy is a chronic neurological disorder associated with abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and rapid eye movement (REM) sleep phenomena including...
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Niemann-Pick Disease Type C Misdiagnosed as Cerebral Palsy: A Case Report

Ko EJ, Sung IY, Yoo HW

Niemann-Pick disease type C (NP-C) is a rare autosomal recessive neurovisceral lysosomal lipid storage disorder. The clinical manifestations of the disorder are variable. This report describes the case of a...
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Parasomnia as an Initial Presentation of Narcolepsy

Kang JJ, Kang HG, Seo MW, Shin BS, Oh SY, Ryu HU

Narcolepsy is characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucinations. Only a few studies have focused on non-rapid eye movement (NREM) and REM parasomnias in narcolepsy. We...
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Comparison of Health Related Quality of Life between Type I and Type II Narcolepsy Patients

Cho JW, Kim DJ, Noh KH, Han J, Jung DS

OBJECTIVES: Narcolepsy with cataplexy is a rare chronic sleep disorder characterized by excessive daytime sleepiness, cataplexy, sleep paralysis, and hypnagogic/hypnopompic hallucinations. The aims of the present study were comparing the...
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Evaluation of Cognitive Functions in Patients with Narcolepsy

Jin YY, Yoon JS, Chung EK

  • KMID: 2285635
  • J Agric Med Community Health.
  • 2013 Jun;38(2):97-107.
OBJECTIVE: This study aimed to evaluate attention, memory and executive function in patients with narcolepsy. METHODS: This study included 23 narcoleptic patients whose diagnosis were confirmed by the International Classification of...
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Effect of clomipramine in a dog with cataplexy

Jeong SY, Kang MH, Park HM

  • KMID: 1991782
  • Korean J Vet Res.
  • 2013 Jun;53(2):129-131.
A 5-year-old, castrated male, Maltese was presented with history of acute flaccid paralysis. The dog was presented with sudden loss of muscle tone and involuntary movements of hind limbs. Neurologic...
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Morphological Changes in Narcolepsy

Joo EY

  • KMID: 2202655
  • J Korean Sleep Res Soc.
  • 2013 Dec;10(2):35-38.
Narcolepsy is a chronic neurological disorder with the abnormal regulation of the sleep-wake cycle, resulting in excessive daytime sleepiness, disturbed nocturnal sleep, and manifestations related to rapid eye movement sleep...
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Late-Onset Narcolepsy with Cataplexy Unresponsive to Intravenous High-Dose Immunoglobulin Treatment

Cho JW, Jung NY, Bae JW, Kim DJ, Lee JH, Kanbayashi T

  • KMID: 2343436
  • J Korean Neurol Assoc.
  • 2012 Feb;30(1):57-59.
Narcolepsy with cataplexy (NC) is associated with hypocretin deficiency, and is thought to be an autoimmunity condition. The mean age at onset is estimated to be in the early 20s....
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Use of PCR with Sequence-specific Primers for High-Resolution Human Leukocyte Antigen Typing of Patients with Narcolepsy

Woo HI, Joo EY, Hong SB, Lee KW, Kang ES

BACKGROUND: Narcolepsy is a neurologic disorder characterized by excessive daytime sleepiness, symptoms of abnormal rapid eye movement (REM) sleep, and a strong association with HLA-DRB1*1501, -DQA1*0102, and -DQB1*0602. Here, we...
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Excessive Daytime Sleepiness Case Confounding with Thyrotoxicosis

Chung JK, Kim EJ

  • KMID: 2317504
  • Sleep Med Psychophysiol.
  • 2011 Jun;18(1):40-44.
Narcolepsy is a sleep disorder, which is characterized by excessive daytime sleepiness (EDS) that is typically associated with cataplexy, sleep fragmentation and other REM sleep-related phenomenon such as sleep paralysis...
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Narcolepsy in Children

Seo WS

  • KMID: 2317500
  • Sleep Med Psychophysiol.
  • 2011 Jun;18(1):17-22.
Childhood narcolepsy is one of the underdiagnosed diseases even the first symptoms often appear in childhood. Making diagnosis through history taking is not always easy because the symptoms of childhood...
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Narcolepsy: Clinical Feature, Diagnosis and Treatment

Shin HB

  • KMID: 2317492
  • Sleep Med Psychophysiol.
  • 2010 Dec;17(2):63-68.
Narcolepsy is a central neurologic system disease. It begins early in life with disabling symptoms including excessive daytime sleepiness, cataplexy, sleep paralysis, hypnagogic hallucination and nocturnal sleep fragmentation. Patient with...
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Gray Matter Concentration Abnormality in Brains of Narcolepsy Patients

Joo EY, Tae WS, Kim ST, Hong SB

OBJECTIVE: To investigate gray matter concentration changes in the brains of narcoleptic patients. MATERIALS AND METHODS: Twenty-nine narcoleptic patient with cataplexy and 29 age and sex-matched normal subjects (mean age,...
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Pediatric Narcolepsy: Diagnosis and Treatment

Bang YW, Chae KY

  • KMID: 2329418
  • J Korean Child Neurol Soc.
  • 2009 Nov;17(2):107-117.
Narcolepsy is chronic devastating disease that characterized by excessive daytime sleepiness, cataplexy, which often precipitated by intense emotion or excitement, hypnagogic, or hypnapompic hallucinations, sleep paralysis and nocturnal disrupted sleep....
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HLA-DQB1 Allele and Hypocretin in Korean Narcoleptics with Cataplexy

Jeong JH, Hong SC, Shin YK, Han JH, Lee SP

Cataplexy is one of the most pathognomonic symptoms in narcolepsy. This study was designed to investigate the frequency of the HLA-DQB1 allele and cerebrospinal fluid (CSF) hypocretin levels in Korean...
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Comparison of Narcolepsy with Cataplexy and without Cataplexy: Clinical Variables, HLA-DQB1*0602, and Hypocretin

Jeong JH, Hong SC, Shin YK, Han JH, Lee SP

  • KMID: 2341266
  • J Korean Neuropsychiatr Assoc.
  • 2007 Jan;46(1):50-57.
OBJECTIVES: Narcolepsy is a sleep disorder, characterized by excessive daytime sleepiness, cataplexy, sleep paralysis and hypnagogic hallucination. Among these symptoms, cataplexy is one of the most pathognomonic symptoms in narcolepsy....
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The effects of modafinil on clinical features and sleep structure of narcolepsy patients and healthy controls

Shin HB, Kim EJ, Jeong DU

  • KMID: 2009979
  • Sleep Med Psychophysiol.
  • 2006 Dec;13(2):67-74.
INTRODUCTION: Excessive daytime sleepiness and cataplexy are key features of narcolepsy. Modafinil is psychostimulant used in the treatment of narcolepsy. In this study, we evaluated effects of modafinil on nocturnal...
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Gender Differences in Narcolepsy Symptomatology among Adolescents

Han EK, Shin YK, Yoon IY

  • KMID: 2317434
  • Sleep Med Psychophysiol.
  • 2005 Dec;12(2):133-138.
OBJECTIVES: Narcolepsy is characterized by excessive sleepiness, cataplexy, sleep paralysis and hypnagogic hallucination. As there have been few researches on narcolepsy symptomatology in adolescents, we examined gender differences and prevalence...
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Decreased Attention in Narcolepsy Patients is not Related with Excessive Daytime Sleepiness

Kim SJ, Lyoo IK, Lee Y, Lee JY, Jeong DU

  • KMID: 2317433
  • Sleep Med Psychophysiol.
  • 2005 Dec;12(2):122-132.
OBJECTIVES: The objective of this study is to assess cognitive functions and their relationship with sleep symptoms in young narcoleptic patients. METHODS: Eighteen young narcolepsy patients and 18 normal controls...
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